Search results for "eutectic"
showing 7 items of 67 documents
19P Deep eutectic solvent mixture formed from 2-deoxy-D-glucose and metformin targets cancer cell metabolism and induces apoptosis in breast cancer c…
2020
26P Cellulose beads prepared in deep eutectic solvent function as carrier and cytoprotective encapsulation matrix for CAR-T cells in T-cell therapy a…
2020
Isoniazid cocrystallisation with dicarboxylic acids: vapochemical, mechanochemical and thermal methods
2016
Cocrystallisation with a series of related compounds allows for the exploration of trends and limitations set by structural differences between these compounds. In this work, we investigate how the length of a dicarboxylic acid influences the outcome of cocrystallisation with isoniazid. We have performed a systematic study on the mechanochemical, thermal and solvent vapour-assisted cocrystallisation of aliphatic dicarboxylic acids (C3–C10) with isoniazid. Our results demonstrate that the rate of mechanochemical and vapour-assisted cocrystallisation depends on the acid chain length and shows alternation between odd- and even-chain acids. The results of thermal cocrystallisation showed that t…
Correction: Polymer-enforced crystallization of a eutectic binary hard sphere mixture
2017
Correction for 'Polymer-enforced crystallization of a eutectic binary hard sphere mixture' by Anna Kozina et al., Soft Matter, 2012, 8, 627-630.
Deep eutectic solvents vs ionic liquids: Similarities and differences
2020
Abstract Deep eutectic solvents (DES) were introduced as an alternative to ionic liquids (IL) to overcome the drawbacks of IL solvents. However, some authors consider them to be a subclass of ILs. In contrast, other authors emphasize that these are by their nature independent, different groups of substances. Thus, the question arises: Which solvent group should DESs belong to? Maybe a new class should be added to the existing ones. The aim of this work is to attract the attention of researchers using DES in their studies to the need for a proper use of terms.
Liquid structure of a choline chloride-water natural deep eutectic solvent: A molecular dynamics characterization
2021
The liquid structure of a representative of the first water-in-salt (WiS) Natural Deep Eutectic Solvents (NADES), hereinafter indicated as aquoline, a mixture of choline chloride (ChCl) and water with molar ratio 1:3.33, is ex- plored at ambient conditions. Using Molecular Dynamics (MD) simulation tools, we extract structural informa- tion at atomistic level on the nature of inter-correlations between the different moieties. Despite being a very fluid liquid, with much lower viscosity than other common ChCl-based DES, aquoline turns out to be very struc- tured. Computed X-ray and neutron weighted scattering patterns (the latter also on selectively deuterated mix- tures) highlight the existe…
Structural Features of β-Cyclodextrin Solvation in the Deep Eutectic Solvent, Reline
2020
The inherently amphiphilic nature of native cyclodextrins (CDs) determines their peculiar molecular encapsulation features, enabling applications such as targeted drug nanodelivery, aroma protection, etc. On the contrary, it may also lead to poor solubility in water and other organic solvents and to potentially detrimental flocking in these media, thus posing limitations to more extensive usage. Here we use small angle X-ray scattering to show that deep eutectic solvent reline (1:2 choline chloride:urea) succeeds in dissolving large amounts of beta-CD (at least 800 mg/mL, compared with the solubility in water of 18 mg/mL), without aggregation phenomena occurring. At the microscopic level, m…