Search results for "evaluation"
showing 10 items of 1974 documents
La rete intercomunale del corleonese per un’azione di prevenzione e lotta al Punteruolo rosso delle palme.
2009
Synthesis and preliminary biological evaluation of a new pyridocarbazole derivative covalently linked to a thymidine nucleoside as a potential target…
2003
The therapy of human cancer is one of the more pursued goals by medicinal chemistry research. Most of the compounds clinically used as a treatment owe their efficacy to their cytotoxic interaction (direct or indirect) with nuclear DNA. This interaction results in the inhibition of DNA synthesis and the degradation of nucleic strands. Ellipticine is a naturally occurring 6H-pyrido[4,3-b]carbazole alkaloid endowed with antitumor activity, and several ellipticine derivatives have been used in clinical trials. We previously reported some 1,4-dimethyl-9H-carbazole derivatives structurally related to ellipticine. The purpose of our research was to transform the pyridocarbazole in a prodrug so tha…
Peut-on parler de recherche en pédagogie universitaire, aujourd'hui, en France ?
2008
08102; Définir la pédagogie universitaire et savoir ce qu'elle recouvre en France en termes de recherche constitue un enjeu. En effet, le manque de visibilité et de lisibilité de ce champ en limitent probablement la portée à l'heure où la notion de qualité semble se faire plus pressante dans le contexte universitaire français. En partant d'une définition opérationnelle de ce que l'on peut entendre par pédagogie universitaire en France et en s'appuyant sur une recherche documentaire effectuée à partir de la base de données Francis ainsi que de la consultation de programmes complets de différents colloques, cet article vise à mettre en perspective et à illustrer les principaux axes de recherc…
A methodology for the sustainability assessment of agri-food systems: an application to the Slow Food Presidia project
2014
New and alternative models for agri-food production and consumption have brought up questions regarding the effects they have on local development processes in terms of the economic exploitation of rural areas as well as environmental, cultural, and social factors. The agri-food system proposed by the Slow Food (SF) Presidia Project, which focuses on farm-to-market systems for local, high-quality, sustainable products, can respond to the new and emerging needs of both rural and urban populaces via several approaches in addition to food production itself. However, evaluating these parameters is challenging. The aim of this study was to develop an indicator-based tool to monitor the sustainab…
La medida de la calidad educativa : acerca de los rankings universitarios
2017
En el presente texto se revisa desde una perspectiva critica la construccion de sistemas transnacionales de evaluacion de la calidad a traves de los rankings internacionales. En la primera parte, reflexionamos sobre el concepto de calidad y presentamos diferentes tipos de rankings: los denominados League Tables (ARWU, THE, QS) y los centrados en resultados de investigacion (SCImago Institutions Ranking). Una vez conocidas las caracteristicas y posibles utilidades de los mismos, analizamos dialogicamente una serie de riesgos a tener en cuenta para acabar incidiendo de nuevo en el modelo de calidad que proponen y sus posibles efectos.
Evaluation of cut quality using the Amadeus microkeratome with different settings.
2004
Abstract Purpose: To evaluate the quality of keratectomy specimens created with the Amadeus® microkeratome (AMO) using scanning electron microscopy (SEM). Setting: Johannes Gutenberg-University Hospital, Department of Ophthalmology, Mainz, and the Department of Anatomy, Justus Liebig-University, Giessen, Germany. Methods: Corneal cuts were performed in freshly enucleated pig eyes using the Amadeus microkeratome with 9 combinations of oscillation rate and head-advance speed. For the cutting trials, oscillation rates of 8000, 13000, and 18000 rpm and head-advance speeds of 1.0, 2.5, and 4.0 mm/s were chosen. Fifty-four eyes were included, resulting in 9 groups of 6 eyes for each configuration…
Opportunities for Strategic Public Relations : Evaluation of International Research and Innovation Project Dissemination
2018
Abstract European industry, academia and potential end users for future solutions are widely involved in applying for European Union (EU) funding of research and innovation and implementation of the projects. Funding instrument requirements emphasise the influence of skills and know-how of these project consortia professionals. This chapter proposes a co-creative model for communication and dissemination, or project PR, based on the experiences of both planning and coordinating dissemination activities of three EU funded projects. Multidisciplinary international project Public Relations (PR) offers strategic opportunities for PR professionals. The model employs the co-creation methods based…
Influence of dental treatment in place on quality of life in oral cancer patients undergoing chemoradiotherapy
2018
Background This study aims to assess, in the population of patients with oral cancer treatment, the influence on the quality of life of two protocols of dental treatment: not ruled hospital treatment versus ruled hospital treatment. Material and Methods A quasi-experimental approach justified on ethical grounds was used. A total of 41 patients were included in the control group (not ruled treatment outpatient health center) and 40 in the experimental group (ruled hospital treatment). A total of 14 questions to both groups were conducted in three stages: before starting cancer treatment, during treatment and after treatment. the proportions of positive responses in groups and different times…
Randomized controlled trial of postoperative exercise rehabilitation program after lumbar spine fusion: study protocol
2012
Abstract Background Lumbar spine fusion (LSF) effectively decreases pain and disability in specific spinal disorders; however, the disability rate following surgery remains high. This, combined with the fact that in Western countries the number of LSF surgeries is increasing rapidly it is important to develop rehabilitation interventions that improve outcomes. Methods/design In the present RCT-study we aim to assess the effectiveness of a combined back-specific and aerobic exercise intervention for patients after LSF surgery. One hundred patients will be randomly allocated to a 12-month exercise intervention arm or a usual care arm. The exercise intervention will start three months after su…
Predicting antitrichomonal activity: A computational screening using atom-based bilinear indices and experimental proofs
2006
Existing Trichomonas vaginalis therapies are out of reach for most trichomoniasis people in developing countries and, where available, they are limited by their toxicity (mainly in pregnant women) and their cost. New antitrichomonal agents are needed to combat emerging metronidazole-resistant trichomoniasis and reduce the side effects associated with currently available drugs. Toward this end, atom-based bilinear indices, a new TOMOCOMD-CARDD molecular descriptor, and linear discriminant analysis (LDA) were used to discover novel, potent, and non-toxic lead trichomonacidal chemicals. Two discriminant functions were obtained with the use of non-stochastic and stochastic atom-type bilinear in…