Search results for "event"
showing 10 items of 4065 documents
The Speed of Incorporating Information into Prices
2013
Abstract To determine the speed of adjusting asset prices to the latest market information, investors usually resort to semi-strong form efficiency tests. Semi-strong form efficiency is based on the assumption that stock prices adjust rapidly as a result of new public information. The objective of the event study conducted in this paper was to examine whether new information is incorporated into the share price in a single price change after its public distribution. We analyzed the price behaviour of companies listed under Category I of the Bucharest Stock Exchange around events such interim result announcements between June and November 2012.
Impacto de las notas de prensa en las citas recibidas por los artículos publicados en Gaceta Sanitaria
2014
Antecedentes/Objetivos: Hay pocos estudios que analicen los factores que influyen sobre el factor de impacto bibliométrico de una revista y las notas de prensa son uno de estos factores. Se presenta un análisis del impacto en las citas recibidas por los artículos objeto de una nota de prensa elaborada desde Gaceta Sanitaria. Métodos: Se elaboró una base de datos con todos los artículos publicados en Gaceta Sanitaria entre 2007 y 2011. Para cada uno se registró el número de citas recibidas hasta el año 2012 (incluido) en la base de datos Web of Science. Para cada artículo se registró si había sido incluido o no en las notas de prensa elaboradas desde la revista. Desde 2007 hasta 2011 dos art…
Evidenz für eine frühzeitige Therapie der COPD mit Tiotropium
2012
Hintergrund: Die Wirksamkeit von Tiotropium versus Kontrolle wurde in einer praspezifizierten Subgruppenanalyse der 4-Jahres-Studie „Understanding Potential Long-term Impacts on Function with Tiotropium“ bei Patienten mit chronisch obstruktiver Lungenerkrankung (COPD) mittleren Schweregrades (GOLD II) untersucht und erstmals den gepoolten Ergebnissen aus den schwereren Krankheitsstadien (GOLD III/IV) gegenubergestellt. Methode: Randomisierte multizentrische, doppelblinde, kontrollierte Studie mit parallelem Gruppenvergleich bei 5993 Patienten uber 4 Jahre. Die Patienten erhielten entweder Tiotropium 18 µg einmal taglich oder Plazebo. Als Endpunkte wurden der jahrliche FEV1-Abfall und weiter…
221 Better Event-Free Survival in Ambulatory Heart Transplant (HTx) Candidates Who Are Physically Active and in Good Mood
2012
(pre-Group1 89.6 6.1 x pre-Group2 89.3 6.9, p 0.8; 1yr97.6 1.1 x 97.1 1.5, p 0.3; 2yr96.8 2.3 x 97.0 1.1,p 0.9,in %); MIP (pre64.0 23.9 x 65.5 24.2, p 0.8; 1yr94.9 25.2 x 98.5 15.6, p 0.7; 2yr93.4 26.6 x 101.3 12.6, p 0.7) and MEP (pre-92 29.1 x 86.5 27.1, p 0.5; 1yr 99.2 28.5 x 104.9 16.4,p 0.9; 2yr 103.14 25 x 105.6 16.4, p 0.7,in cmH2O) and 6MWT (pre-428 137.4 x 411.2 113.9, p 0.5; 1yr 629.2 91.26 x 659.2 93.5, p 0.3; 2yr 645.9 91.5 x 686.6 98.6, p 0.2,in meters). Conclusions: Our findings indicate that unsupervised rehabilitation may represent an alternative in the management of post lung transplant patients.
European Respiratory Society statement on sleep apnoea, sleepiness and driving risk
2021
Obstructive sleep apnoea (OSA) is highly prevalent and is a recognised risk factor for motor vehicle accidents (MVA). Effective treatment with continuous positive airway pressure has been associated with a normalisation of this increased accident risk. Thus, many jurisdictions have introduced regulations restricting the ability of OSA patients from driving until effectively treated. However, uncertainty prevails regarding the relative importance of OSA severity determined by the apnoea–hypopnoea frequency per hour and the degree of sleepiness in determining accident risk. Furthermore, the identification of subjects at risk of OSA and/or accident risk remains elusive. The introduction of off…
Protocol for the EARCO Registry
2020
Rationale and objectives Alpha-1 antitrypsin deficiency (AATD) is a genetic condition that leads to an increased risk of emphysema and liver disease. Despite extensive investigation, there remain unanswered questions concerning the natural history, pathophysiology, genetics and the prognosis of the lung disease in association with AATD. The European Alpha-1 Clinical Research Collaboration (EARCO) is designed to bring together researchers from European countries and to create a standardised database for the follow-up of patients with AATD. Study design and population The EARCO Registry is a non-interventional, multicentre, pan-European, longitudinal observational cohort study enrolling patie…
Escala de desarrollo armónico (EDA): Una propuesta para la evaluación clínica del desarrollo infantil desde la Teoría de Sistemas
2020
Los profesionales de las ciencias de la salud y de la educación necesitan herramientas adecuadas para llevar a cabo la prevención de los trastornos del desarrollo infantil. La Escala de Desarrollo Armónico –EDA–, se presenta como una propuesta que permite la coordinación interdisciplinaria y la colaboración de los educadores. La escala se ha construido para observar el ascenso del paisaje epigenético individual desde el paradigma de los sistemas dinámicos. Para lograrlo, se han estudiado parámetros que pueden explicar la evolución del sistema –índice de armonía y cociente de desarrollo estable–, un mecanismo del cambio –tirón cognitivo– y fuerzas moldeadoras –velocidad y cristalización–, si…
Phytochemical Indicaxanthin Inhibits Colon Cancer Cell Growth and Affects the DNA Methylation Status by Influencing Epigenetically Modifying Enzyme E…
2015
<b><i>Background:</i></b> Recently, we have shown anti-proliferative and pro-apoptotic effects of indicaxanthin associated with epigenetic modulation of the onco-suppressor <i>p16</i><sup><i>INK4a</i></sup> in the human colon cancer cell line CACO2. In the present study, the epigenetic activity of indicaxanthin and the mechanisms involved were further investigated in other colorectal cancer cell lines. <b><i>Methods:</i></b> LOVO1, CACO2, HT29, HCT116, and DLD1 cells were used to evaluate the potential influence of consistent dietary concentrations of indicaxanthin on DNA methylation, and the epigenetic mech…
Association between Tpeak-Tend/QT and major adverse cardiovascular events in patients with Takotsubo syndrome
2020
Background:Conflicting results have been described in the scientific literature regarding the relationship between electrocardiographic parameters and complications in patients with Takotsubo syndrome (TTS). Aim of the present study was to investigate whether there is an association between markers of ventricular repolarization and major adverse cardiovascular events (MACE) during hospitalisation. Methods:A retrospective chart review was conducted on a sample of patients with diagnosis of TTS, based on the fulfilment of the revised Mayo Clinic criteria. MACE included acute heart failure, cardiogenic shock, sustained ventricular tachycardia, ventricular fibrillation, and death. The following…
Patterns of Safety Incidents in a Neonatal Intensive Care Unit
2021
Introduction: Safety incidents preceding manifest adverse events are barely evaluated in neonatal intensive care units (NICUs). This study aimed at identifying frequency and patterns of safety incidents in our NICU.Methods: A 6-month prospective clinical study was performed from May to October 2019 in a German 10-bed level III NICU. A voluntary, anonymous reporting system was introduced, and all neonatal team members were invited to complete paper-based questionnaires following each particular safety incident. Safety incidents were defined as safety-related events that were considered by the reporting team member as a “threat to the patient's well-being” which “should ideally not occur agai…