Search results for "eventi"
showing 10 items of 2167 documents
In vitro antifungal properties of mouthrinses containing antimicrobial agents
1997
The purpose of this study was to investigate the in vitro antifungal properties of seven commercial mouthrinses containing antimicrobial agents. These included cetylpyridinium chloride (CPC), chlorhexidine digluconate (CHX), hexetidine (HEX), sanguinarine (SNG), and triclosan (TRN). The minimum fungicidal concentration (MFC) against six species of yeasts was determined by a broth macrodilution method. The kill-time of mouthrinses at half the concentration of the commercial formulations was also determined. MFCs were achieved with each mouthrinse, except the SNG-containing mouthrinse, against all the organisms being tested. However, the CPC-containing mouthrinse appeared more active than the…
Dietary polyphenols in chemoprevention and synergistic effect in cancer: Clinical evidences and molecular mechanisms of action
2020
Abstract Background Epidemiological studies has revealed that a diet rich in fruits and vegetables could lower the risk of certain cancers. In this setting, natural polyphenols are potent anticancer bioactive compounds to overcome the non-target specificity, undesirable cytotoxicity and high cost of treatment cancer chemotherapy. Purpose The review focuses on diverse classifications of the chemical diversity of dietary polyphenol and their molecular targets, modes of action, as well as preclinical and clinical applications in cancer prevention. Results The dietary polyphenols exhibit chemo-preventive activity through modulation of apoptosis, autophagy, cell cycle progression, inflammation, …
Regression Modeling of the Antioxidant-to-Nephroprotective Relation Shows the Pivotal Role of Oxidative Stress in Cisplatin Nephrotoxicity
2021
The clinical utility of the chemotherapeutic drug cisplatin is significantly limited by its nephrotoxicity, which is characterized by electrolytic disorders, glomerular filtration rate decline, and azotemia. These alterations are consequences of a primary tubulopathy causing injury to proximal and distal epithelial cells, and thus tubular dysfunction. Oxidative stress plays a role in cisplatin nephrotoxicity and cytotoxicity, but its relative contribution to overall toxicity remains unknown. We studied the relation between the degree of oxidative reduction (provided by antioxidant treatment) and the extent of nephrotoxicity amelioration (i.e., nephroprotection) by means of a regression anal…
Prophylaxis of Non-communicable Diseases: Why fruits and vegetables may be better chemopreventive agents than dietary supplements based on isolated p…
2019
The World Health Organization (WHO) report from 2014 documented that non-communicable socalled civilization diseases such as cardiovascular disease, chronic respiratory diseases, cancer or type 2 diabetes are responsible for over 50% of all premature deaths in the world. Research carried out over the past 20 years has provided data suggesting that diet is an essential factor influencing the risk of development of these diseases. The increasing knowledge on chemopreventive properties of certain food ingredients, in particular, those of plant origin, opened the discussion on the possibility to use edible plants or their active components in the prevention of these chronic diseases. Health-pro…
Influence of cultivar and concentration of selected phenolic constituents on the in vitro chemiopreventive potential of olive oil extracts.
2011
One of the main olive oil phenolic compounds, hydroxytyrosol (3,4-DHPEA), exerts in vitro chemopreventive activities (antiproliferative and pro-apoptotic) on tumor cells through the accumulation of H2O2 in the culture medium. However, the phenol composition of virgin olive oil is complex, and 3,4-DHPEA is present at low concentrations when compared to other secoiridoids. In this study, the in vitro chemopreventive activities of complex virgin olive oil phenolic extracts (VOO-PE, derived from the four Italian cultivars Nocellara del Belice, Coratina, Ogliarola, and Taggiasca) were compared to each other and related to the amount of the single phenolic constituents. A great chemopreventive po…
Perceived benefits and constraints in vehicle automation: Data to assess the relationship between driver's features and their attitudes towards auton…
2019
This data article examines the association driver's features, perceptions and attitudes towards autonomous vehicles (AVs). The data was collected using a structured self-administrable and online-based questionnaire, applied to a full sample of 1205 Spanish drivers. The data contains 4 parts: the full set of bivariate correlations between study variables; descriptive statistics and graphical trends for each main study variable according to gender, age group and city/town size; and, finally, the dataset for further explorations in this regard. For more information, it is convenient to read the full article entitled “Perceived safety and attributed value as predictors of the intention to use a…
Termini Imerese: rilettura topografica per un’ipotesi restitutiva dell’impianto urbano
2018
I risultati che si presentano in questa sede sono frutto di una rivisitazione dello stato dell’arte, facilitata dall’informatizzazione dei dati topografici, dall’implementazione di una piattaforma GIS e dalla reperibilità di supporti cartografici a dettagli sempre maggiori. La rilettura topografica dell’edito si è posta come obiettivo la ricostruzione virtuale della potenziale maglia urbana dell’antica Thermae, quello che viene definito in genere il piano programmatico, in attesa che nuovi rinvenimenti contribuiscano a ridefinire le dimensioni del modulo di base e soprattutto quelle reali degli isolati abitativi. Il confronto con fondazioni coeve e culturalmente affini (Solunto, in primo lu…
Archéologie préventive. Une ressource pour la recherche et la mise en valeur?
2014
This paper discusses the results in applying Italy's law in preventive archaeology five years after the publication of the executive rules. It examines strenghts and weaknisses of the law, the latter identified in the scant attention paid to ancient topography and landscape archaeology. The role of university departments, the responsabilities of the Superintendences, the role of cooperatives of young archaeologists, the problems arising from the heavy costs in publishing the reserach results are examined. It is also proposed that the archaeological exavations and the programs of musealization be financed by a national fund fed by a percentage of the costs of all projects of public interest.
On the impact of safety requirements, energy prices and investment costs in street lighting refurbishment design
2018
Abstract Street lighting is an indispensable feature for the night landscape of cities. It is important for road safety, users visual comfort, crime prevention and to augment the perceived personal safety. Realize and maintain an adequate street lighting service is very expensive for municipalities with significant impact on their budgets. For this reason, special attention should be paid to the design of new street lighting systems and to the refurbishment of existing ones, since many of them are inadequate. In light of this it is very important to implement street lighting designs that fulfil lighting requirements avoiding energy waste and light pollution and, at the same time, result eco…
The rural dwelling of the Second Iron Age
2013
This book, resulting from a national investigation conducted by Inrap, is an analytical presentation of the rhythms of the emergence and abandonment of rural settlements during the Second Iron Age in the northern half of France. Depending on the region studied, between the 5th century BC and the 1st century AD, rural settlements were established, and have now been studied through preventative archaeological operations covering large surfaces. These studied updated our knowledge of the Gallic countryside, integrating paleobotanical, zooarchaeological and climatic data. Through systematic studies and presentations, this book offers a useful glimpse into this period, linking archaeology and hi…