Search results for "eyes"

showing 10 items of 125 documents

Antonii Gomezii ... Ad leges tauri commentarium absolutissimum

1780

Frisos, vinyetes i caplletres ornades Sign.: []2, A-Z, Aa-Zz, Aaa-Rrr6, Sss-Ttt4 Port. a 2 tintes. - Text a 2 col. - Notes a peu de p. - Reclams. - Errates de Pag.

Leyes de Toro Comentaris Obres anteriors al 1800Leyes de Toro Comentaris Obres anteriors a 1800
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Contexto editorial, cultural y socio-político de la edición príncipe de la «Historia de la doncella Teodor» (Toledo: Pedro Hagenbach, 1500-1501)

2021

The material analysis of the only surviving copy of the editio princeps of the Historia de la doncella Teodor allows us to date it back to the incunabula era and to attribute its printing to Pedro Hagenbach’s workshop. The close relationship amongst Hagenbach’s workshop, the reformist project of Archbishop Cisneros, and the interests of the Catholic Monarchs sets an editorial and cultural context that supports the adaptation of Teodor to the printing press. This work perfectly agreed with the thematic and ideological guidelines for the renewal of Christian customs and values. The forceful religious and intellectual imposition of the young and learned slave, turned into a “fijadalgo” in the …

Linguistics and LanguageHistoryLiterature and Literary TheoryArchbishopmedia_common.quotation_subjectCultural contextHistoria de la doncella TeodorContext (language use)Forced conversionLanguage and Linguisticslaw.inventionPrinting pressPoliticsPedro HagenbachClose relationshiplawPropaganda políticaIdeologyReyes CatólicosHumanitiesEdición príncipemedia_common
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La divisa de las granadas del rey Enrique IV de Castilla y su estela posterior

2015

ABSTRACT: This study analyzes the meaning of the impresa or device of the pomegranates, with the motto « Agro dulce », utilized by Henry IV (1425-1474), of the House of Trastamara, King of Castile from 1454 until his death. By means of a review of vestiges that remain of the device, especially in architectonic elements, I postulate that the pomegranate may have been used as the family impresa of the House of Trastamara and their descendants. This, it seems, can be deduced from the pictura of the device in several personal imprese of relatives who lived in the sixteenth century. KEYWORDS: pomegranate, devices, royal clemency, Henry IV, Catholic Monarchs, Catherine of Aragon, Charles V, Phili…

Linguistics and LanguageVisual Arts and Performing ArtsCommunicationmedia_common.quotation_subjectHastaArtHenry IV Holy Roman EmperorLanguage and LinguisticsMeaning (semiotics)Filología Hispánica Historia del Arte Cultura visual europea Edad Moderna EmblemáticaHumanitiesCartographygranada divisas clemencia real Enrique IV Reyes Católicos Catalina de Aragón Carlos V Felipe IImedia_common
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Functional Plasticity after Unilateral Vestibular Midbrain Infarction in Human Positron Emission Tomography.

2016

The aim of the study was to uncover mechanisms of central compensation of vestibular function at brainstem, cerebellar, and cortical levels in patients with acute unilateral midbrain infarctions presenting with an acute vestibular tone imbalance. Eight out of 17 patients with unilateral midbrain infarctions were selected on the basis of signs of a vestibular tone imbalance, e.g., graviceptive (tilts of perceived verticality) and oculomotor dysfunction (skew deviation, ocular torsion) in F18-fluordeoxyglucose (FDG)-PET at two time points: A) in the acute stage, and B) after recovery 6 months later. Lesion-behavior mapping analyses with MRI verified the exact structural lesion sites. Group su…

Male0301 basic medicineBrain Stem Infarctionslcsh:MedicinePathology and Laboratory MedicineMidbrainDiagnostic Radiology0302 clinical medicineThalamusMesencephalonCortex (anatomy)Medicine and Health SciencesMedicinelcsh:ScienceTomographyPostural BalanceVestibular systemNeuronal PlasticityMultidisciplinaryRadiology and ImagingBrainAnatomyFrontal eye fieldsMagnetic Resonance Imagingmedicine.anatomical_structureVestibular DiseasesInfarctionThalamic NucleiFemaleBrainstemAnatomyBrainstemResearch ArticleImaging TechniquesThalamusNeuroimagingResearch and Analysis Methods03 medical and health sciencesSigns and SymptomsDiagnostic MedicineOcular SystemHumansSkew deviationAgedbusiness.industrylcsh:RBiology and Life SciencesVestibular cortex030104 developmental biologyVisual cortexCase-Control StudiesPositron-Emission TomographyLesionsEyeslcsh:QbusinessHeadNeurosciencePositron Emission Tomography030217 neurology & neurosurgeryNeurosciencePLoS ONE
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Effectiveness of anti-vascular endothelial growth factors in neovascular age-related macular degeneration and variables associated with visual acuity…

2021

Objective To assess the overall effectiveness of anti-vascular endothelial growth factor (VEGF) therapy in treatment-naïve patients with neovascular age-related macular degeneration (nAMD) in a clinical practice setting. Study design EAGLE was a retrospective, 2-year, cohort observational, multicenter study conducted in Italy that analyzed secondary data of treatment-naïve patients with nAMD. The primary endpoint evaluated the mean annualized number of anti-VEGF injections at Years 1 and 2. The main secondary endpoints analyzed the mean change in visual acuity (VA) from baseline and variables associated with visual outcomes at Years 1 and 2. Results Of the 752 patients enrolled, 745 (99.07…

MaleEaglesAntiVEGF Drugs nAMD clinical practiceVisual AcuitySocial SciencesRetinal NeovascularizationInfographicsGeographical locationsMacular DegenerationMedical ConditionsEndocrinologyRetrospective StudieClinical endpoint80 and overPsychologyAged 80 and overEukaryotaItalyCohortMedicineHumanmedicine.medical_specialtyScienceDrug Administration ScheduleFollow-Up StudieSigns and Symptomsbiology.animalLinear regressionHumansAgedRetrospective StudiesSettore MED/30 - Malattie Apparato VisivoData VisualizationOrganismsBiology and Life Sciencesmedicine.diseaseOphthalmologyMacular DisordersLesionsEyesObservational studyClinical MedicinePeople and placesNeuroscienceVascular Endothelial Growth Factor AVisual acuityTime FactorsEye DiseasesVisionPhysiologyAngiogenesis InhibitorsMedicine and Health SciencesGeriatric OphthalmologyData ManagementMultidisciplinarybiologyQRetinal DegenerationRChartsEuropeAged; Aged 80 and over; Angiogenesis Inhibitors; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Intravitreal Injections; Italy; Macular Degeneration; Male; Retinal Neovascularization; Retrospective Studies; Time Factors; Treatment Outcome; Vascular Endothelial Growth Factor A; Visual AcuityTreatment OutcomeVertebratesIntravitreal InjectionsRetinal DisordersSensory PerceptionFemalemedicine.symptomAnatomyAngiogenesis InhibitorResearch ArticleEagleComputer and Information SciencesTime FactorBirdsOcular SystemInternal medicineSettore MED/30Growth FactorsmedicineAnimalsEuropean UnionRaptorsEndocrine Physiologybusiness.industryIntravitreal InjectionCognitive PsychologyRetrospective cohort studyMacular degenerationGeriatricsAmniotesCognitive SciencePerceptionbusinessZoologyHeadFollow-Up Studies
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Association of ocular, cardiovascular, morphometric and lifestyle parameters with retinal nerve fibre layer thickness.

2017

BACKGROUND Glaucoma is a neurodegenerative disease, leading to thinning of the retinal nerve fibre layer (RNFL). The exact influence of ocular, cardiovascular, morphometric, lifestyle and cognitive factors on RNFL thickness (RNFLT) is unknown and was analysed in a subgroup of the Gutenberg Health Study (GHS). METHODS Global peripapillary RNFLT was measured in 3224 eyes of 1973 subjects (49% female) using spectral-domain optical coherence tomography (SD-OCT). The association of age, sex, ocular, cardiovascular, morphometric, lifestyle and cognitive factors on RNFLT was analysed using Pearson correlation coefficient and fitting a linear mixed model. RESULTS In the univariable analysis highest…

MaleHomocysteineEye Diseasesgenetic structuresGlaucomalcsh:MedicineBlood PressureOtologyVascular MedicineDiagnostic Radiologychemistry.chemical_compoundTinnitus0302 clinical medicineNerve FibersAnimal CellsMedicine and Health SciencesProspective StudiesProspective cohort studylcsh:Science610 Medicine & healthTomographyHearing DisordersAged 80 and overNeuronsMultidisciplinaryAlcohol ConsumptionRadiology and ImagingAxial lengthMiddle AgedAxial Length EyeLifestyle factorsNeurologyRegression AnalysisFemaleCellular TypesAnatomyTomography Optical CoherenceResearch ArticleAdultmedicine.medical_specialtyImaging TechniquesNerve fibre layer610 Medicine & healthHomocysteine levelsResearch and Analysis MethodsRetina03 medical and health sciencesSex FactorsOcular SystemDiagnostic MedicineOphthalmologymedicineHumansddc:610Life StyleAgedNutritionbusiness.industryMorphometrylcsh:RBiology and Life SciencesRetinalGlaucomaCell Biologymedicine.diseaseeye diseasesDietOphthalmologychemistryOtorhinolaryngologyCellular Neuroscience030221 ophthalmology & optometryEyeslcsh:Qsense organsbusinessHead030217 neurology & neurosurgeryNeuroscience
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The Evonik-Mainz Eye Care-Study (EMECS): Development of an Expert System for Glaucoma Risk Detection in a Working Population

2015

Purpose To develop an expert system for glaucoma screening in a working population based on a human expert procedure using images of optic nerve head (ONH), visual field (frequency doubling technology, FDT) and intraocular pressure (IOP). Methods 4167 of 13037 (32%) employees between 40 and 65 years of Evonik Industries were screened. An experienced glaucoma expert (JW) assessed papilla parameters and evaluated all individual screening results. His classification into “no glaucoma”, “possible glaucoma” and “probable glaucoma” was defined as “gold standard”. A screening model was developed which was tested versus the gold-standard. This model took into account the assessment of the ONH. Valu…

MaleIntraocular pressureEye Diseasesgenetic structuresOptic disklcsh:MedicineGlaucomacomputer.software_genreNerve Fibers0302 clinical medicineCost of IllnessRisk FactorsAnimal CellsOdds RatioPrevalenceMedicine and Health SciencesMedicine030212 general & internal medicinelcsh:ScienceNeuronsMultidisciplinaryPharmaceuticsApplied MathematicsSimulation and ModelingMiddle AgedVisual fieldPhysical SciencesFemaleAnatomyCellular TypesAlgorithmsResearch ArticleAdultmedicine.medical_specialtyOptic DiskResearch and Analysis MethodsSensitivity and SpecificityDiagnosis DifferentialTonometry Ocular03 medical and health sciencesDrug TherapyOcular SystemOphthalmologyHumansWorking populationIntraocular PressureAgedbusiness.industrylcsh:RBiology and Life SciencesGlaucomaOptic NerveCell BiologyOdds ratioGold standard (test)medicine.diseaseeye diseasesExpert systemOphthalmologyCellular Neuroscience030221 ophthalmology & optometryVisual Field TestsEyesOptometrylcsh:Qsense organsVisual FieldsbusinessHeadcomputerMathematicsNeurosciencePLOS ONE
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Influence of Corneal Opacity on Intraocular Pressure Assessment in Patients with Lysosomal Storage Diseases

2017

Aims To investigate an influence of mucopolysaccharidosis (MPS)- and Morbus Fabry-associated corneal opacities on intraocular pressure (IOP) measurements and to evaluate the concordance of the different tonometry methods. Methods 25 MPS patients with or without corneal clouding, 25 Fabry patients with cornea verticillata ≥ grade 2 and 25 healthy age matched controls were prospectively included into this study. Outcome measures: Goldmann applanation tonometry (GAT); palpatory assessment of IOP; Goldmann-correlated intraocular pressure (IOPg), corneal-compensated intraocular pressure (IOPcc), corneal resistance factor (CRF) and corneal hysteresis (CH) assessed by Ocular Response Analyzer (ORA…

MaleIntraocular pressureVisual acuityEye Diseasesgenetic structuresVisionVisual AcuitySocial Scienceslcsh:MedicineGlaucomaCorneaCorneal Opacity0302 clinical medicineCorneaMedicine and Health SciencesPsychologyCornea verticillatalcsh:ScienceOptical PropertiesMultidisciplinaryCorneal opacityMiddle Agedmedicine.anatomical_structurePhysical SciencesSensory PerceptionFemaleAnatomyCellular Structures and Organellesmedicine.symptomStatistics (Mathematics)Research ArticleOpacityAdultmedicine.medical_specialtyAdolescentOcular AnatomyMaterials ScienceMaterial PropertiesCorneal hysteresis03 medical and health sciencesOcular SystemOphthalmologyConfidence IntervalsmedicineHumansIn patientIntraocular PressureAgedbusiness.industrylcsh:RBiology and Life SciencesGlaucomaCell BiologyMucopolysaccharidosesmedicine.diseaseeye diseasesOphthalmology030221 ophthalmology & optometryEyeslcsh:Qsense organsLysosomesbusinessHeadMathematics030217 neurology & neurosurgeryNeurosciencePLOS ONE
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Prevalence of corneal arcus and associated factors in a German population-Results from the Gutenberg Health Study.

2021

Purpose We aimed to determine the prevalence of corneal arcus and to identify associated factors in the general population of Germany. Methods The Gutenberg Health Study (GHS) is a population-based cohort study in Germany, which includes an ophthalmological assessment. Refraction, distance-corrected visual acuity, non-contact tonometry and anterior segment imaging were performed for the five-year follow-up examination. Anterior segment photographs were graded for the presence of corneal arcus. Prevalence estimates were computed, and multivariable logistic regression analysis was applied to determine associated factors for corneal arcus including sex, age, spherical equivalent, central corn…

MaleIntraocular pressureVisual acuitygenetic structuresVisual AcuityBlood PressureCardiovascular MedicineBiochemistryVascular MedicineGeographical locationsCorneaMedical ConditionsEndocrinologyCorneaGermanyMedicine and Health SciencesPrevalenceProspective StudiesDioptreeducation.field_of_studyMultidisciplinaryQRMiddle AgedLipidsEuropemedicine.anatomical_structureCholesterolCardiovascular DiseasesMedicineFemalemedicine.symptomAnatomyCohort studyResearch Articlemedicine.medical_specialtyEndocrine DisordersOcular AnatomySciencePopulationCardiologyArcus SenilisOcular SystemOphthalmologymedicineDiabetes MellitusHumansEuropean UnioneducationIntraocular Pressurebusiness.industryBiology and Life SciencesCardiovascular Disease Riskmedicine.diseaseeye diseasesBlood pressureCross-Sectional StudiesMetabolic DisordersEyessense organsPeople and placesbusinessHeadDyslipidemiaPLoS ONE
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Efficacy and safety of preoperative IOP reduction using a preservative-free fixed combination of dorzolamide/timolol eye drops versus oral acetazolam…

2017

Introduction To demonstrate that preoperative treatment for 28 days with topical dorzolamide/timolol is non-inferior (Δ = 4 mm Hg) to oral acetazolamide and topical dexamethasone (standard therapy) in terms of intraocular pressure (IOP) reduction 3 and 6 months after trabeculectomy in glaucoma patients. Materials and methods Sixty-two eyes undergoing trabeculectomy with mitomycin C were included in this monocentric prospective randomized controlled study. IOP change between baseline and 3 months post-op was defined as the primary efficacy variable. Secondary efficacy variables included the number of 5-fluorouracil (5-FU) injections, needlings, suture lyses, preoperative IOP change, hyperten…

MaleIntraocular pressuregenetic structuresEye DiseasesPhysiologymedicine.medical_treatmentTimololGlaucomalcsh:Medicine030204 cardiovascular system & hematologyDexamethasone0302 clinical medicineGlaucoma surgeryMedicine and Health SciencesMedicineTrabeculectomyProspective Studieslcsh:ScienceSulfonamidesMultidisciplinaryPharmaceuticsDorzolamide/TimololOphthalmic ProceduresMiddle AgedDrug CombinationsTreatment OutcomeResearch DesignAnesthesiaTimololFemaleFluorouracilAnatomyAcetazolamidemedicine.drugResearch Articlemedicine.medical_specialtyLysis (Medicine)Clinical Research DesignSurgical and Invasive Medical ProceduresTrabeculectomyThiophenesResearch and Analysis Methods03 medical and health sciencesMusculoskeletal System ProceduresDorzolamideDrug TherapyOcular SystemOphthalmologyTissue RepairPreoperative CareHumansAntihypertensive AgentsIntraocular PressureAgedbusiness.industrylcsh:RBiology and Life SciencesGlaucomamedicine.diseaseeye diseasesAcetazolamideOphthalmology030221 ophthalmology & optometryEyeslcsh:QOcular Hypertensionsense organsAdverse EventsOphthalmic SolutionsbusinessPhysiological ProcessesHeadPLoS ONE
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