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showing 10 items of 11436 documents

The Influence of Nanoparticle Shape on Protein Corona Formation

2020

Nanoparticles have become an important utility in many areas of medical treatment such as targeted drug and treatment delivery as well as imaging and diagnostics. These advances require a complete understanding of nanoparticles' fate once placed in the body. Upon exposure to blood, proteins adsorb onto the nanoparticles surface and form a protein corona, which determines the particles' biological fate. This study reports on the protein corona formation from blood serum and plasma on spherical and rod‐shaped nanoparticles. These two types of mesoporous silica nanoparticles have identical chemistry, porosity, surface potential, and size in the y ‐dimension, one being a sphere and the other a …

rod shapeSurface Propertiesnanoparticle shapeNanoparticleProtein Corona02 engineering and technology010402 general chemistry01 natural sciencesBiomaterialsCorona (optical phenomenon)protein coronaAdsorptionBlood serumDrug Delivery SystemsGeneral Materials ScienceChemistryAlbuminsphere shapeGeneral ChemistryMesoporous silica021001 nanoscience & nanotechnologySilicon Dioxideprotein adsorption0104 chemical sciences3. Good healthBiophysicsbio-nanoparticle interactionsNanoparticlesProtein Corona0210 nano-technologymesoporous nanoparticlesBiotechnologyProtein adsorption
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Expressions multiplicatives en textos catalans medievals

2015

Explicitació i aclariment de passatges amb expressions multiplicatives en textos medievals en català: (1) "Estar en quatre tants" (Facet); (2) "A cent doblàries" (Vita Christi d'Isabel de Villena); (3) "Doble és l'afany" (poema 1 d'Ausiàs March). An explicitation and clarification of three medieval Catalan texts' passages with multiplicative expressions: (1) "Estar en quatre tants" (Facet); (2) "A cent doblàries" (Vita Christi by Isabel de Villena); (3) "Doble és l'afany" (Ausiàs March, poem 1).

romance languagesUNESCO::CIENCIAS DE LAS ARTES Y LAS LETRASIsabel de Villenamedieval cultureLiteratura catalana medievalliteratura catalana medievalmedieval catalan literaturecultura medievalmedieval catalancatalà medievalExpressions multiplicativesaritmètica medievalAusiàs Marchmedieval arithmetics:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]facetFilología Catalanafacetusllengües romàniques
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Safety and immunogenicity of the therapeutic vaccine TG1050 in chronic hepatitis B patients: a phase 1b placebo-controlled trial

2020

Funding: Transgène; International audience; Treatment of chronic hepatitis B (CHB) typically requires life-long administration of drugs. Cohort and pre-clinical studies have established the link between a functional T-cell-mounted immunity and resolution of infection. TG1050 is an adenovirus 5-based vaccine that expresses HBV polymerase and domains of core and surface antigen and has shown immunogenicity and antiviral effects in mice. We performed a phase 1 clinical trial to assess safety and explore immunogenicity and early efficacy of TG1050 in CHB patients. This randomized, double blind, placebo-controlled study included two sequential phases: one single dose cohort (SD, n = 12) and one …

safetyHBsAg030231 tropical medicineImmunologyPlacebo-controlled studyPhases of clinical researchSciences du Vivant [q-bio]/Médecine humaine et pathologieimmunogenicityPlaceboAntiviral AgentsAdenoviridae03 medical and health sciencesMice0302 clinical medicineHepatitis B ChronicImmunogenicity VaccinevaccineImmunology and AllergyMedicineAnimalsHumans030212 general & internal medicineAdverse effectPharmacologyVaccinesHepatitis B Surface Antigens[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologybusiness.industryELISPOTImmunogenicitychronicityimmuno-therapyHepatitis Bmedicine.diseaseHepatitis B3. Good healthImmunologybusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyResearch Paper
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Assessing HYDRUS-2D model to simulate water content and salt accumulation in a soil irrigated with a subsurface drip system: Application in a semiari…

2015

In this paper, the suitability of HYDRUS-2D model to predict the average soil water content in the root zone of potato crop irrigated with subsurface drip irrigation plant, is initially assessed on the basis of a field study. Then, the model is tested to predict the salt distribution around a buried emitter, when two different water qualities (i.e. electrical conductivity of 1.0 dS m-1 and 4.0 dS m-1), are used during the growing season (treatments T1 and T2). Finally, the soil volume in which salts accumulates, as well as the effects on crop yield is recognized for both the considered treatments.The results evidenced that predicted values of average soil water content in the root zone were…

salt accumulationsubsurface drip irrigationSettore AGR/08 - Idraulica Agraria E Sistemazioni Idraulico-ForestaliHYDRUS-2D Subsurface drip irrigation salt accumulation potato cropHYDRUS-2DHYDRUS-2D; subsurface drip irrigation; salt accumulation; potato croppotato crop
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Combined effect of low-molecular-weight organic acids and creosote on phosphatase activities in sandy soil

2018

This paper assesses the impact of creosote and low-molecular-weight organic acids (LMWOAs) on the activity of acid phosphomonoesterase, alkaline phosphomonoesterase, phosphotriesterase, and inorganic pyrophosphatase in soil. The experiment was carried out on loamy sand samples with organic carbon content of 8.71 g · kg -1 , with the following variable factors: dosages of creosote: 0, 0.5%, and 2.5%; type of LMWOAs: oxalic acid, tartaric acid, and citric acid in the amount of 50 mmol · kg -1 of soil; days of experiment: 1, 7, 14, 28, 56, 112. Obtained results showed that contamination with creosote caused decrease in the activity of soil phosphatases. The observed effect did not always incre…

sandy loamOxalic acidPhosphataseSoil Science010501 environmental sciences01 natural sciencesoxalic acidlaw.inventionchemistry.chemical_compoundlawcreosotephosphatases0105 earth and related environmental sciencesEarth-Surface ProcessesTotal organic carbonEcology04 agricultural and veterinary sciencescitric acidSoil contaminationCreosotechemistrytartaric acidLoamEnvironmental chemistry040103 agronomy & agricultureTartaric acid0401 agriculture forestry and fisheriesCitric acidPolish Journal of Soil Science
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Quasi Phase Matched UV Second Harmonic Generation in Lithium Tantalate soft PE Waveguides

2008

We report on first experimental results on UltraViolet second-harmonic generation by first-order quasiphase-matching in a surface periodically poled proton exchanged Lithium Tantalate waveguide. We have achieved a good compatibility with alpha phase proton exchanged channel waveguides in Lithium Tantalate. We held the sample in a temperature controlled oven kept at a constant temperature of 250 °C, to reduce photorefractive damage. The pump source was a Ti-Sapphire laser with a tunability range of 700 - 980 nm and a 40-GHz linewidth. Continuous wave UV light at 365.4 nm was produced with a conversion efficiency of 6.6% W-1cm-2.

second harmonic generationLithium Tantalatesurface periodic poling
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Stress sensitivity of stylolite morphology

2009

International audience; Stylolites are rough surfaces that form by localized stress-induced dissolution. Using a set of limestone rock samples collected at different depths from a vertical section in Cirque de Navacelles (France), we study the influence of the lithostatic stress on the stylolites morphology on the basis of a recent morphogenesis model. We measured the roughness of a series of bedding-parallel stylolites and show that their morphology exhibits a scaling invariance with two self-affine scaling regimes separated by a crossover-length (L) at the millimeter scale consistent with previous studies. The importance of the present contribution is to estimate the stylolite formation s…

self-affine scalingMorphology (linguistics)010504 meteorology & atmospheric sciences[SDU.STU.GP]Sciences of the Universe [physics]/Earth Sciences/Geophysics [physics.geo-ph]MineralogyMagnitude (mathematics)morphogenesisSurface finish010502 geochemistry & geophysics01 natural sciencesStress (mechanics)Geochemistry and Petrology[SDU.STU.GC]Sciences of the Universe [physics]/Earth Sciences/GeochemistryEarth and Planetary Sciences (miscellaneous)Geotechnical engineeringpaleo-stressScaling0105 earth and related environmental sciencesroughness[SDU.STU.TE]Sciences of the Universe [physics]/Earth Sciences/TectonicsDeformation (mechanics)stylolitesStress fieldGeophysicsSpace and Planetary ScienceStyloliteGeology[SDU.STU.MI]Sciences of the Universe [physics]/Earth Sciences/Mineralogy
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Who Can See My Stuff? : Online Self-Disclosure and Gender Differences on Facebook

2018

This study investigates the gendered privacy practices and concerns on Facebook, by leaning on the idea of privacy management as a form of digital labour. We analyse if young Facebook users are more concerned about the privacy against other users than against Facebook as a company or against third-party partners. We also analyse if privacy concerns and visibility rules are differentiated by gender. Using a structured online survey, we collected responses from a sample of 813 Italian university students (aged 18-34). Our results show that the respondents have just slightly more privacy concerns against other users than against Facebook, and much less against third-party partners. Unlike a ma…

self-disclosure gender visibility rules privacy management FacebookFacebookComputer Networks and CommunicationsInternet privacyprivacy management050801 communication & media studiesSample (statistics)visibility rulessukupuoli0508 media and communicationsyksityisyysgenderta518Everyday lifebusiness.industryCommunication05 social sciencesVisibility (geometry)050301 educationta5142Privacy managementta5141Self-disclosureself-disclosurebusinessPsychologynäkyvyys0503 educationyksilönsuojaObservatorio (OBS*)
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Toward a stage theory of adaptive social media use : explaining change in facebook use

2018

Existing research on information technology (IT) use has shown that post- adoptive technology use is not a stable but a dynamic phenomenon in which users apply various adaptation behaviors. Users reshape the technology (IT adaptation), adjust their work routines (task adaptation), and change their own behavior (user adaptation) according to the changes induced by IT. Today, people use increasingly social media and other IT for personal purposes. Facebook (FB) is a good example of personal IT that people voluntarily use for years and has become an integral part of people’s everyday lives. Despite extensive research on IT use and IT/user adaptation, we know little about the dynamics of post-a…

self-regulationuser adapatationIT useFacebookkäyttäjätstage theorytottumuksetuser adaptationsosiaalinen mediavaiheteoriatelinkaarimuutositsesäätelykäyttöpost-adoptionkäyttäjätutkimus
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Modālo darbības vārdu lietojums uzņēmuma “Printful” Facebook publikācijās

2022

Uzņēmumiem ir tendence regulāri publicēt atbilstošu saturu sociālo mediju platformās, lai digitāli reklamētu savas preces vai pakalpojumus. Tāpēc šī darba mērķis bija izpētīt, kā viena gada laikā atšķiras modālo darbības vārdu lietojums “Printful” Facebook publikācijās. Mērķa sasniegšanai kā pētījuma metodes tika izvēlētas biežuma un semantiskā analīze. Empīriskā daļa bija vērsta uz modālo un daļēji modālo darbības vārdu biežumu un to semantiskajām funkcijām “Printful” Facebook 2021. gada publikācijās. Rezultāti parādīja, ka visbiežāk lietotie modālie darbības vārdi bija “will” un “can”, bet retāk lietots ir “may”. Visbiežāk modālo darbības vārdu skaits mēnesī svārstījās no 21 līdz 30. Visb…

semantiskās funkcijasValodniecībamodālie darbības vārdibiežuma analīzesemantiskā analīzeFacebook publikācijas
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