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showing 10 items of 6421 documents
Androgēnie anaboliskie steroīdi, to ietekme uz veselību un izplatība sabiedrības vidū
2016
Ārējais izskats spēj ietekmēt apkārtējo sabiedrības viedokli, veidojot priekšstatu par cilvēka raksturu un spējām. Izsenis cilvēkus ieinteresējis, kā izmantojot mazāku piepūli iegūt pievilcīgāku ķermeņa izskatu un labāku sportisko sniegumu. Lai sasniegtu mērķi cilvēki dažkārt ir gatavi izmēģināt visdažādākos līdzekļus, lai gan tiem ir risks pasliktināt veselību un izraisīt nopietnas blakusparādības. Šī darba mērķis bija noskaidrot, vai Latvijā ir izplatīta androgēno anabolisko steroīdu lietošana, kādi ir to lietošanas paradumi un, kurš no testosterona līdzekļiem BENU aptieku tīklā ir vispieprasītākais laika posmā no 2013. gada 1. janvāra līdz 2015. gada 31. decembrim. Pēc iegūtajiem aptauju…
Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin-4-(thi)one derivatives.
2002
Several 2,3-diaryl-1,3-thiazolidine-4-thione derivatives and 2,3-diaryl-1,3-thiazolidin-4-ones bearing a methyl group at C-5 position have been synthesized and tested as anti-HIV agents. The results of the in vitro tests showed that some of them proved to be effective inhibitors of HIV-1 replication.
2-cinnamamido, 2-(3-phenylpropiolamido) and 2-(3-phenylpropanamido)benzamides: synthesis, antiproliferative activity and mechanism of action
2013
Several new 2-cinnamamido, 2-(3-phenylpropiolamido) and 2-(3-phenylpropanamido)benzamides were synthesized by stirring in pyridine the opportune acid chlorides with the appropriate anthranilamide derivatives. Some of the synthesized compounds were evaluated for their in vitro antiproliferative activity against a panel of 5 human cell lines (K562 human chronic myelogenous leukemia cells, MCF-7 breast cancer cells, HTC-116 and HT26 colon cancer cells and NCI H460 non-small cell lung cancer cells).
Synthesis and biological evaluation of some new 2-cinnamidobenzamides as potential antagonist of the HDM2-p53 protein-protein interactions
2008
2021
Animal Welfare Attitudes (AWA) are defined as human attitudes towards the welfare of animals in different dimensions and settings. Demographic factors, such as age and gender are associated with AWA. The aim of this study was to assess gender differences among university students in a large convenience sample from twenty-two nations in AWA. A total of 7914 people participated in the study (5155 women, 2711 men, 48 diverse). Participants completed a questionnaire that collected demographic data, typical diet and responses to the Composite Respect for Animals Scale Short version (CRAS-S). In addition, we used a measure of gender empowerment from the Human Development Report. The largest varia…
Revisiting agricultural modernisation: Interconnected farming practices driving rural development at the farm level
2019
Abstract Rural development related to agriculture can roughly be divided into two trajectories: 1) agri-industrial development or modernisation, and 2) multifunctional or even post-productivist rural development. The role of these trajectories varies in different rural settings, with different emphases on agricultural production and its conduct. At the farm level, the trajectories evolve from existing farming practices and their connections, which enable or disable different kinds of development. However, the connections through which changes in agricultural production practices contribute to different rural development trajectories deserve further scrutiny. This is addressed with the help …
2. tipa cukura diabēta ārstēšanai paredzēto medikamentu aprite aptiekā un ar to lietošanu saistītās blakusparādības
2020
2. tipa cukura diabēts ir viena no izplatītākajām slimībām pasaulē, izraisot mikrovaskulāras un makrovaskulāras komplikācijas. Slimība ir hroniska un progresē pēc 45 gadu vecuma saistībā ar nepilnvērtīgu uzturu un mazkustīgu dzīvesveidu. Katru gadu 2. tipa cukura diabēta pacientu skaits pieaug un līdz ar to arī antidiabētisko līdzekļu patēriņš. Darba mērķis bija izpētīt 2. tipa cukura diabēta ārstēšanai paredzēto medikamentu apriti aptiekā un ar antidiabētisko medikamentu lietošanu saistītās blakusparādības. Pētījuma rezultāti liecina, ka 2. tipa cukura diabēta ārstēšanai vairāk tiek izrakstīti perorālie antidiabētiskie medikamenti, no kuriem populārākā antidiabētisko medikamentu grupas zāļ…
Effects of the coronavirus disease 2019 pandemic on the number of hospitalizations for myocardial infarction: regional differences. Population analys…
2020
Lower ST-elevation myocardial infarction incidence during COVID-19 epidemic in Northern Europe
2020
We compared the ST elevation myocardial infarction (STEMI) incidence during COVID-19 pandemic (March 2020) to January-February 2020 and to same time period in earlier years 2017-2019 in five Nordic-Baltic tertiary centers. During 2017-2019, there were no marked differences in STEMI incidence between January, February and March. During 2020, there was an average drop of 32% in STEMI incidence in March. The isolation measures may decrease the risk for respiratory virus infection and contribute to the lower STEMI incidence and that we might benefit from firmer suggestions on hand hygiene and social distancing during flu season at least among high-risk individuals.
Children Witnessing Domestic and Family Violence: A Widespread Occurrence during the Coronavirus Disease 2019 (COVID-19) Pandemic
2021
Across the world, children and adolescents are exposed daily to toxic levels of violent behaviors, including domestic and family violence. Violence increasingly has permeated and profoundly affected the lives of children, who are the most vulnerable members of society.1 Pediatric societies in Europe and North America have raised great concern over the effect that abusive experiences will have on present and future generations.1, 2, 3, 4 The global spread of coronavirus disease 2019 (COVID-19) during the past year has dramatically worsened the situation, contributing to a further increase in violence and aggression within households. Reports of domestic abuse and family violence have increas…