Search results for "feature"
showing 10 items of 4091 documents
In syringe hybrid monoliths modified with gold nanoparticles for selective extraction of glutathione in biological fluids prior to its determination …
2020
Abstract In this work, a simple device for extraction glutathione (GSH) in biological fluids using a hybrid monolithic material within a polypropylene syringe is developed. For this purpose, glycidyl methacrylate-based monolith was firstly prepared within this housing material, and the polymer was modified with different ligands (ammonia, cysteamine and cystamine). The resulting materials (containing amine or thiol groups, respectively) were then functionalized with gold nanoparticles (AuNPs). The hybrid material that gave the largest AuNPs coverage was selected as solid-phase (SPE) sorbent and several variables affecting the extraction recovery of this compound were investigated. Under opt…
Extraction of β-blockers from urine with a polymeric monolith modified with 1-allyl-3-methylimidazolium chloride in spin column format
2020
Abstract A glycidyl methacrylate-based monolith was modified with imidazolium-based ionic liquid (IL) to be used as stationary phase for solid-phase extraction (SPE). The host monolithic support was prepared by in-situ UV polymerization in spin column format. Two approaches were developed to incorporate the IL into the polymeric monolithic matrix: generation of IL onto the surface monolith, and copolymerization by addition of the IL to the polymerization mixture, which gave the best results. The resulting sorbent materials were morphologically characterized and used for the isolation of five β-blockers from human urine samples. All SPE steps were accomplished by centrifugation, which reduce…
Synthesis and evaluation of a glibenclamide glucose-conjugate: a potential new lead compound for substituted glibenclamide derivatives as islet imagi…
2007
The search for novel SUR1-ligands originates from the idea to influence the in vivo behaviour by adding new structural moieties to the glibenclamide structure while preserving its binding affinity. Important application of novel conjugates might be their use as radioactively labelled tracer probes in the non-invasive investigation of the islet mass. It is known that the imaging quality of a tracer could be improved by increasing its hydrophilicity, which leads to a reduced plasma protein binding and diminished the unspecific uptake by various organs. In this study the glucose molecule was chosen as a substitute of glibenclamide to enhance hydrophilicity. As expected glucose conjugation lead…
Pan-African granulite formation in the Kabye Massif of northern Togo (West Africa): Pb−Pb zircon ages
2000
Metamorphic zircons from seven granulite facies orthogneisses of tonalitic composition (ender- bites), collected from four different nappes of the Kabye Massif in the Dahomeyide belt of northern Togo, were dated by the Pb-Pb evaporation method. They yielded consistent Neoproterozoic ages with a mean of 612.5 0.8 Ma, interpreted to reflect the peak of regional granulite facies metamorphism following Pan-African continental collision between the West African and Benin-Nigerian plates. These results sup- port previous ages obtained by various chronometers on high-grade rocks from the same suture zone and from surrounding units in Togo, Benin and Ghana. They are also similar to zircon ages fr…
Middle Miocene graben development in Crete and its possible relation to large-scale detachment faults in the southern Aegean
2001
The linkage between the development of south-facing Cretan graben and large-scale detachment faulting in the southern Aegean is unknown. Widespread Serravallian deposits in the Ierapetra graben of Crete supply constraints to Middle Miocene graben development in the southern Aegean. The Ierapetra graben, and by inference the Cretan graben in general, were hitherto believed to have formed as a result of sinistral transpression during N–S shortening. We argue that the formation of the Cretan graben is due to N–S extension. The south-dipping, N–S-extending Kritsa normal fault served as the master fault controlling graben development in the Ierapetra graben. The Kritsa normal fault is either an …
Resurgent uplift at large calderas and relationship to caldera-forming faults and the magma reservoir: new insights from the Neapolitan Yellow Tuff c…
2021
<p>Resurgence uplift is the rising of the caldera floor, mainly due to pressure or volume changes in the magma reservoir. Identifying resurgence structures and understanding their relationship to the magmatic reservoir is challenging. We investigate the resurgence structures of the Neapolitan Yellow Tuff (NYT) caldera (Italy) by integrating bathymetric data, high-resolution seismic profiles and Differential Synthetic-Aperture Radar Interferometry data. Our results show that the resurgent area is manifested as 1) a central dome constituted by two main blocks bounded by NNE-SSW trending faults, 2) an apical graben developed on top of the most uplifted block, 3) a peripheral zone…
Geodynamic Setting of the Tertiary Hocheifel Volcanism (Germany), Part I: 40Ar/39Ar geochronology
2007
The Eifel volcanism is part of the Cenozoic Central European Volcanic Province and is located close to the Rhine Graben which has been formed by rifting and subsidence since the Eocene. Whereas the Quaternary volcanism of the Eifel appears to be genetically related to mantle plume activity, the cause of the Tertiary volcanism of the Hocheifel volcanic field is less clear. Here, we present geochronological evidence for the geotectonic setting of the Tertiary Eifel volcanism based on 40Ar/39Ar dating of 27 samples from 25 volcanic occurrences. Included are samples from the northern Upper Rhine Graben in order to evaluate a possible relationship between Hocheifel volcanism and Rhine Graben tap…
Semisupervised nonlinear feature extraction for image classification
2012
Feature extraction is of paramount importance for an accurate classification of remote sensing images. Techniques based on data transformations are widely used in this context. However, linear feature extraction algorithms, such as the principal component analysis and partial least squares, can address this problem in a suboptimal way because the data relations are often nonlinear. Kernel methods may alleviate this problem only when the structure of the data manifold is properly captured. However, this is difficult to achieve when small-size training sets are available. In these cases, exploiting the information contained in unlabeled samples together with the available training data can si…
GrassPlot v. 2.00 : first update on the database of multi-scale plant diversity in Palaearctic grasslands
2019
Abstract: GrassPlot is a collaborative vegetation-plot database organised by the Eurasian Dry Grassland Group (EDGG) and listed in the Global Index of Vegetation-Plot Databases (GIVD ID EU-00-003). Following a previous Long Database Report (Dengler et al. 2018, Phyto- coenologia 48, 331–347), we provide here the first update on content and functionality of GrassPlot. The current version (GrassPlot v. 2.00) contains a total of 190,673 plots of different grain sizes across 28,171 independent plots, with 4,654 nested-plot series including at least four grain sizes. The database has improved its content as well as its functionality, including addition and harmonization of header data (land use,…
Modeling Volcanic Eruption Parameters by Near-Source Internal Gravity Waves
2016
AbstractVolcanic explosions release large amounts of hot gas and ash into the atmosphere to form plumes rising several kilometers above eruptive vents, which can pose serious risk on human health and aviation also at several thousands of kilometers from the volcanic source. However the most sophisticate atmospheric models and eruptive plume dynamics require input parameters such as duration of the ejection phase and total mass erupted to constrain the quantity of ash dispersed in the atmosphere and to efficiently evaluate the related hazard. The sudden ejection of this large quantity of ash can perturb the equilibrium of the whole atmosphere triggering oscillations well below the frequencie…