Search results for "fide"

showing 10 items of 1978 documents

A Methodology for Modeling and Optimizing Social Systems

2020

[EN] A system methodology for modeling and optimizing social systems is presented. It allows constructing dynamical models formulated stochastically, i.e., their results are given by confidence intervals. The models provide optimal intervention ways to reach the stated objectives. Two optimization methods are used: (1) to test strategies and scenarios and (2) to optimize with a genetic algorithm. The application case presented is a small nonformal education Spanish business. First, the model is validated in the 2008-2012 period, and subsequently, the optimal way to obtain a maximum profit in the 2013-2025 period is obtained using the two methods.

0209 industrial biotechnologyMathematical optimizationComputer scienceStochastic modellingEconomical model02 engineering and technologyConfidence intervalSocial systems020901 industrial engineering & automationStochastic modelGenetic algorithmArtificial IntelligenceSocial systemGenetic algorithm0202 electrical engineering electronic engineering information engineering020201 artificial intelligence & image processingSystem methodologySensitivity analysisMATEMATICA APLICADASoftwareSimulationStrategies and scenariosInformation Systems
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Lying Cheating Robots : Robots and Infidelity

2018

Love has been described as unpredictable, immeasurable and non-purchasable and as such, poses challenges for anyone in a relationship to both stay in love, and to not fall in love with someone else. Scientists are still discovering whether or not love follows any specific recipe. Outlooks, personality, sense of humor and talent may not perfectly guarantee an individual falls in love with another, and more importantly is able to sustain that relationship. This article portrays a futuristic scenario in which truly intelligent and emotional robots already exist. Here, the bi-directional love discussed in Lovotics is not simulated through engineering, but rather is genuine from the perspectives…

0209 industrial biotechnologyuskottomuusComputer sciencemedia_common.quotation_subjectCheating02 engineering and technologytekoälyOutcome (game theory)050105 experimental psychologyHuman–robot interaction020901 industrial engineering & automationrakkaustunteetAffectionPersonality0501 psychology and cognitive sciencesmedia_commonSexual attraction05 social sciencesseksihuman-robotrobotitRobotpsykologiainfidelityLyingSocial psychology
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Me, My Bot and His Other (Robot) Woman? Keeping Your Robot Satisfied in the Age of Artificial Emotion

2018

With a backdrop of action and science fiction movie horrors of the dystopian relationship between humans and robots, surprisingly to date-with the exception of ethical discussions-the relationship aspect of humans and sex robots has seemed relatively unproblematic. The attraction to sex robots perhaps is the promise of unproblematic affectionate and sexual interactions, without the need to consider the other&rsquo

0209 industrial biotechnologyuskottomuusControl and Optimizationlcsh:Mechanical engineering and machinery02 engineering and technologytekoälyemotions050105 experimental psychology020901 industrial engineering & automationtunteetsex0501 psychology and cognitive scienceslcsh:TJ1-1570Artificial emotionsRelation (history of concept)ta113Dystopiabusiness.industryMechanical Engineering05 social sciencesInformation technologyRoboticsartificial intelligencePreferenceAction (philosophy)seksirobotitRobotrobotsArtificial intelligenceinfidelitybusinessPsychologyCognitive psychology
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Urban upbringing and childhood respiratory and allergic conditions: A multi-country holistic study

2018

Objective: We integratively assessed the effect of different indoor and outdoor environmental exposures early in life on respiratory and allergic health conditions among children from (sub-) urban areas. Methods: This study included children participating in four ongoing European birth cohorts located in three different geographical regions: INMA (Spain), LISAplus (Germany), GINIplus (Germany) and BAMSE (Sweden). Wheezing, bronchitis, asthma and allergic rhinitis throughout childhood were assessed using parental-completed questionnaires. We designed “environmental scores” corresponding to different indoor, green- and grey-related exposures (main analysis, a-priori-approach). Cohort-specific…

0301 basic medicine05 Environmental SciencesIndoor exposureFirst year of lifeMicrobial loadToxicologyBiochemistryGrey spaceAllergic rhinitis03 medical and health sciences0302 clinical medicineGermanyEnvironmental healthmedicineHumansRespiratory systemChildRespiratory SoundsGeneral Environmental ScienceAsthmaSwedenGreen space2. Zero hungerbusiness.industryEnvironmental ExposureOdds ratio06 Biological Sciencesmedicine.diseaseRhinitis AllergicAsthmaConfidence intervalConfirmatory factor analysis3. Good health030104 developmental biology030228 respiratory systemSpainBronchitisEnvironmental Pollutants03 Chemical SciencesbusinessAllergic Rhinitis ; Asthma ; Green Space ; Grey Space ; Indoor Exposure ; Microbial LoadMulti countryEnvironmental Research
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Anakinra drug retention rate and predictive factors of long-term response in systemic juvenile idiopathic arthritis and adult onset still disease

2019

Background and Objective: Only a few studies have reported long-term efficacy of interleukin (IL)-1 inhibition in systemic juvenile idiopathic arthritis (sJIA) and adult-onset Still disease (AOSD). Herein we report on the effectiveness of anakinra (ANA), expressed in terms of drug retention rate (DRR), and evaluate the predictive factors of drug survival in a cohort of patients with sJIA and AOSD. Patients and Methods: This is a multicenter study reviewing retrospectively the medical records from 61 patients with sJIA and 76 with AOSD, all treated with ANA in 25 Italian tertiary referral centers. Results: The cumulative retention rate of ANA at 12-, 24-, 48-, and 60-month of follow-up was 7…

0301 basic medicineAdult onset Still diseasemedicine.medical_specialtyArthritisStill DiseaseAdult onset Still disease; Anakinra; Drug retention rate; Innovative biotechnologies; Interleukin 1-beta; Personalized medicine; Systemic juvenile idiopathic arthritis03 medical and health sciences0302 clinical medicineSettore MED/38 - Pediatria Generale E Specialisticaanakinra interleukin 1-beta innovative biotechnologies drug retention rate systemic juvenile idiopathic arthritis adult onset Still disease personalized medicineSystemic juvenile idiopathic arthritisInternal medicinemedicinePharmacology (medical)Adverse effectOriginal ResearchPharmacologyAnakinrabusiness.industryHazard ratiolcsh:RM1-950Innovative biotechnologiesmedicine.diseaseDrug retention ratePersonalized medicineConfidence intervalAdult onset Still disease Anakinra Drug retention rate Innovative biotechnologies Interleukin 1-beta Personalized medicine Systemic juvenile idiopathic arthritisDiscontinuation030104 developmental biologylcsh:Therapeutics. PharmacologyAnakinraInnovative biotechnologie030220 oncology & carcinogenesisCohortInterleukin 1-betabusinessmedicine.drug
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Type of chromosome abnormality affects embryo morphology dynamics.

2016

Objective To study the differences in the cleavage time between types of embryo chromosomal abnormalities and elaborate algorithm to exclude aneuploid embryos according to the likelihood to be euploid. Design Retrospective cohort study. Setting University affiliated private center. Patient(s) Preimplantational genetic screening patients (n = 112) including cases of advanced maternal age, repeated implantation failure, and recurrent miscarriage. A total of 485 embryos were analyzed. Intervention(s) None. Main Outcome Measure(s) All biopsied embryos were cultured in an incubator with time-lapse technology, cleavage timing from insemination to day 3 and all kinetic parameters that have been de…

0301 basic medicineAdultBiopsyAneuploidyEmbryonic DevelopmentChromosome DisordersFertilization in VitroBiologyTime-Lapse ImagingAndrology03 medical and health sciences0302 clinical medicinePredictive Value of TestsPregnancyRisk FactorsRecurrent miscarriagemedicineOdds RatioChromosomes HumanHumansAdvanced maternal ageGenetic TestingPreimplantation DiagnosisRetrospective StudiesGeneticsChromosome AberrationsComparative Genomic Hybridization030219 obstetrics & reproductive medicineMicroscopy VideoObstetrics and GynecologyRetrospective cohort studyEmbryoOdds ratiomedicine.diseaseAneuploidyConfidence intervalKinetics030104 developmental biologyBlastocystLogistic ModelsReproductive Medicineembryonic structuresChromosome abnormalityFemaleFertility and sterility
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Occupational Heat Exposure and Breast Cancer Risk in the MCC-Spain Study.

2021

Background: Mechanisms linking occupational heat exposure with chronic diseases have been proposed. However, evidence on occupational heat exposure and cancer risk is limited. Methods: We evaluated occupational heat exposure and female breast cancer risk in a large Spanish case-control study. We enrolled 1,738 breast cancer cases and 1,910 frequency-matched population controls. A Spanish job exposure matrix, MatEmEsp, was used to assign estimates of the proportion of workers exposed (P greater than or equal to 25% for at least one year) and work time with heat stress (wet bulb globe temperature ISO 7243) for each occupation. We used three exposure indices: ever vs. never exposed, lifetime c…

0301 basic medicineAdultHot TemperatureEpidemiologyPopulationJob-exposure matrixCumulative ExposureBreast NeoplasmsDisease03 medical and health sciences0302 clinical medicineBreast cancerRisk FactorsEnvironmental healthOccupational ExposureMedicineHumanseducationAgedAged 80 and overeducation.field_of_studybusiness.industryConfoundingOdds ratioMiddle Agedmedicine.diseaseConfidence intervalOccupational Diseases030104 developmental biologyOncologySpain030220 oncology & carcinogenesisCase-Control StudiesFemalebusiness
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Incidence of Stent Thrombosis after Endovascular Treatment of Iliofemoral or Caval Veins in Patients with the Postthrombotic Syndrome.

2019

Abstract Background Patients with postthrombotic syndrome (PTS) treated with stents are at risk of stent thrombosis (ST). The incidence of ST in the presence and absence of anticoagulation therapy (AT) is unknown. Risk factors are not well understood. Patients and Methods From the prospective Swiss Venous Stent registry, we conducted a subgroup analysis of 136 consecutive patients with PTS. Incidence of ST was estimated from duplex ultrasound or venography, and reported for the time on and off AT. Baseline, procedural, and follow-up data were evaluated to identify factors associated with ST. Results Median follow-up was 20 (interquartile range [IQR] 9–40) months. AT was stopped in 43 (32%) …

0301 basic medicineAdultMalemedicine.medical_specialty2720 HematologyVenographySubgroup analysis610 Medicine & healthVena Cava Inferior030204 cardiovascular system & hematologyIliac VeinPostthrombotic Syndrome03 medical and health sciences0302 clinical medicineFibrinolytic AgentsInterquartile rangeRisk FactorsmedicineAlloysHumansCumulative incidenceRegistries610 Medicine & healthStrokemedicine.diagnostic_testbusiness.industryIncidence (epidemiology)10031 Clinic for AngiologyIncidenceHazard ratioEndovascular ProceduresAnticoagulantsThrombosisHematologyPhlebographyFemoral VeinMiddle Agedmedicine.diseaseConfidence intervalSurgery030104 developmental biologyTreatment OutcomeFemaleStentsbusinessSwitzerlandFollow-Up StudiesThrombosis and haemostasis
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Prevalence and Potential Risk Factors of Helicobacter pylori Infection among Asymptomatic Individuals in Kazakhstan

2021

Background: Helicobacter pylori (H. pylori) infection is associated with several risk factors such as demographic, socioeconomic status and personal habits, which vary in different populations. This is the most up-to-date data on H. pylori prevalence and potential risk factors for H. pylori infection among asymptomatic middle-aged individuals in Kazakhstan. Methods: Apparently healthy individuals aged 40 to 64, who took part in the health control in the outpatient clinic, were invited to participate in the study; answered a questionnaire, donated a blood sample. The antibodies to H. pylori were analysed by latex agglutination method. The baseline characteristics of study subjects with or wi…

0301 basic medicineAdultMalemedicine.medical_specialtyprevalenceLogistic regressionAsymptomaticHelicobacter Infections03 medical and health sciences0302 clinical medicineRisk FactorsInternal medicinemedicineOdds RatioOutpatient clinicHumansSalt intakeAsymptomatic InfectionsbiologyHelicobacter pyloribusiness.industrygastric cancerAge FactorsGeneral MedicineOdds ratioAnthropometryHelicobacter pyloriMiddle Agedbiology.organism_classificationConfidence intervalKazakhstanDiet030104 developmental biologyLogistic ModelsSocioeconomic Factors030220 oncology & carcinogenesisFemalemedicine.symptombusinessResearch ArticleAsian Pacific Journal of Cancer Prevention : APJCP
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Ovarian stimulation for oocyte vitrification does not modify disease-free survival and overall survival rates in patients with early breast cancer

2019

Research question: Does ovarian stimulation for oocyte vitrification affect disease-free survival and overall survival rates in women with early breast cancer? Design: This cohort study included 259 patients with early breast cancer; 148 patients underwent ovarian stimulation, whereas 111 patients did not. Patients were treated between January 2008 and December 2016. To calculate the disease-free survival time and overall survival rate, the time of definitive surgery was defined as the starting point. The follow-up was conducted up to 5 years. Results: Exposed and non-exposed groups were comparable in tumour, node and metastases classification, Nottingham grade, hormonal receptor status, tu…

0301 basic medicineAdultmedicine.medical_specialtyAdolescentDisease-free survivalStimulationBreast NeoplasmsKaplan-Meier EstimateOverall survival rateGastroenterologyDisease-Free Survival03 medical and health sciencesYoung Adult0302 clinical medicineBreast cancerBreast cancerOvulation InductionInternal medicinemedicineHumansFertility preservationProspective StudiesStage (cooking)Neoplasm MetastasisFertility preservationRetrospective StudiesCryopreservation030219 obstetrics & reproductive medicinebusiness.industryObstetrics and GynecologyFertility PreservationHistologymedicine.diseaseVitrificationConfidence intervalSurvival Rate030104 developmental biologyTreatment OutcomeReproductive MedicineOocytesFemaleOvarian stimulationNeoplasm Recurrence LocalbusinessDevelopmental BiologyCohort studyHormoneFollow-Up Studies
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