Search results for "fire"
showing 10 items of 463 documents
In Vitro Percutaneous Penetration of Acyclovir from Solvent Systems and Carbopol 971-P Hydrogels: Influence of Propylene Glycol
2005
The mechanism underlying propylene glycol (PG) effects on acyclovir (ACV) penetration through human epidermis were studied. Solvent systems and Carbopol gels containing increasing percentage of PG (from 0% to 70%, w/w) were used. Viscosity studies of both vehicles were carried out to characterise the influence of rheological behaviour. In solvent systems skin permeation values of ACV increase as the concentration of PG increase yielding a maximum enhancement ratio (ER = 10) for 70% PG. The release rate of ACV from gels was determined. Higuchi's model was used to estimate the apparent diffusion coefficient of the drug. These values show a decrease as the content of PG in the vehicle increase…
Enhancement of nortriptyline penetration through human epidermis: influence of chemical enhancers and iontophoresis.
2008
Abstract Different known percutaneous chemical enhancers and iontophoresis have been tested in-vitro to study their ability to increase transdermal absorption of nortriptyline hydrochloride (20 mg mL−1). The chemicals 1-dodecanol, Span 20, Azone, (R)-(+)-limonene or isopropyl myristate were used as an overnight pretreatment at 5% (w/w) in ethanol. Furthermore, isopropyl myristate (20%, w/w) and propylene glycol (15%, w/w) were tested in the same vehicle. Iontophoresis was applied directly to the nortriptyline hydrochloride donor solution for three different concentrations (20, 2 and 0.5 mgmL−1). The chemical enhancers slightly increased the nortriptyline transdermal flux but iontophoresis w…
The decline of the cork oak growing in Sicily is accompanied by the loss of the functions proper to agroforestry systems
2021
The cork oak is one of the most important tree species in the Mediterranean basin, where it covers more than 2 million hectares. Among evergreen oaks, Quercus suber stands out for the variety of cultural systems in which it has been successfully employed, including typical agroforestry systems. Accordingly, a wide range of ecosystem services may be associated to cork oak, including the preservation of biodiversity, carbon sequestration and forage production. In the Mediterranean, the cork oak represents a key species for many natural and seminatural landscapes and habitats, as well as playing a prominent role for the economic and social development of local communities. However, there is in…
Holocene treeline in the northern Andes (Ecuador): new evidence from soil charcoals
2006
Soil charcoals represent a record for palaeoecological studies. For the first time pedoanthracology is applied to northern Andes of Ecuador to study the Holocene treeline. The first results show that the upper treeline was lower than today in the late Pleistocene and in the Middle Holocene. A wide amount of charcoals dated ca. 13000 cal. yr. BP could be caused by fires linked to the first presence of man at these altitudes.
Android lietotne pārbaudījumu izveidei un kopīgošanai
2018
Android lietotnes “CreaTEst” mērķis ir apvienot izglītības iestāžu darbiniekus, entuziastus, kuriem ir vēlme dalīties labās prakses piemēros, komunicēt un iedvesmot. Šāds risinājums ļaus ieviest pārmaiņas pirmsskolas un skolas izglītības iestāžu mācību procesā. Lietotne tiek izstrādāta Java programmēšanas valodā Android Studio izstrādes vidē. Kvalifikācijas darba ietvaros tiks izstrādāti 3 moduļi, kas ļauj publicēt pārbaudījumu jautājumus, kurus izdomājis pats lietotājs. Par katru pievienoto testu autoram ir iespēja saņemt atsauksmes un ieteikumus no pārējiem lietotājiem. Tāpat lietotne sniedz iespēju lejupielādēt testu PDF formātā, lai vēlāk izdrukātu un izsniegtu mācību stundā. Datu glabā…
Lietojumprogrammatūra pasākumu organizēšanai
2018
Kvalifikācijas darbā ir izstrādāta Android lietotne pasākumu organizācijai. Lietotne sastāv no četrām daļām. Pirmajā (galvenajā) daļā «Pasākumi», lietotājs var apskatīt dažādes aktivitātes un var tām pievienoties. Pasākumi dalās 3 dažādos tipos: • «Publiskie (Public) pasākumi» – pasākumi, kuros ir piekļuve visiem lietotājiem, ar dalībnieku skaita ierobežojumu. • «Masu pasākumi» – pasākumi, kuros ir piekļuve visiem lietotājiem, bez dalībnieku skaita ierobežojuma. • «Slēgtie pasākumi» – pasākumi, kuriem ir ierobežots lietotāju loks. Otrajā daļā «Manas aktivitātes» lietotājs var izveidot jebkura tipa pasākumu, kontrolēt un rediģēt jau izveidotos pasākumus un apskatīt tekošos pasākumus, ar kuri…
Lietotu preču apmaiņas lietotne
2021
Kvalifikācijas darba mērķis ir izstrādāt mobilo lietotni, kura nodrošinās dažādu preču apmaiņu. Lietotāji var gan piedāvāt preces, gan pasūtīt citu lietotāju piedāvātās preces. Katrai precei jāpievieno vismaz viens attēls un atkarībā no tās tipa jāaizpilda tipam specifiski lauki. Lietotāji var mainīt preces redzamību sistēmā, rediģēt tās datus un izdzēst to no sistēmas, ja tā nav bijusi pasūtīta. Pēc preces pasūtīšanas pasūtītājs saņem piedāvātāja kontaktus un piedāvātājs saņem pasūtīšanas paziņojumu ar pasūtītāja epastu. Lai nodrošinātu lietotāju datu drošību, pasūtītājs saņem piedāvātāja kontaktus tikai pēc preces pasūtīšanas. Legālu preču apmaiņas nodrošināšanai, sistēmu pārrauga adminis…
Enhanced In Situ Availability of Aphanizomenon Flos-Aquae Constituents Entrapped in Buccal Films for the Treatment of Oxidative Stress-Related Oral D…
2019
In recent years, the key role of oxidative stress in pathogenesis of oral diseases has been emphasized and the use of antioxidant agents has been encouraged. Aphanizomenon flos-aquae (AFA) is a unicellular blue-green alga with antioxidant and anti-inflammatory properties. The aim of this study was the formulation and characterization of mucoadhesive thin layer films loaded with AFA, finalized to the treatment of oxidative stress (OS)-related oral diseases. First, to enhance the bioavailability of AFA constituents, the raw food grade material was appropriately treated by a high frequency homogenization able to disrupt cell walls. Thus, Eudragit®
On Pathways for Small Molecules Into and Out of Human Hair Fibers
1996
This paper represents an experimental approach of histology of the human hair fiber in dyeing and diffusion phenomena and its contribution to the interpretation of hair analysis results for drug abuse. Rhodamine B was applied to human hair fibers from either aqueous solution or methanol/ethanol solvent. The experiments were performed on natural hair of different ethnic groups as well as on extensively bleached hair strands. The microscopical study of the pathway of diffusion of rhodamine B into the hair fibers indicated that the reagent had entered the unmodified fibers at the scale edges between the cuticle cells. At the beginning of the diffusion process intercellular diffusion was the pr…
A modelistic approach showing the importance of the stagnant aqueous layers in in vitro diffusion studies, and in vitro-in vivo correlations
1991
Abstract The present study deals with the role of the aqueous diffusion layers on the in vitro penetration of xenobiotics across artificial lipoidal membranes, and their ability to reproduce biophysical absorption models when in vivo results are to be simulated from the in vitro tests. The aqueous boundary layers which are invariably formed on artificial lipoidal membranes can be optionally preserved or disrupted, according to the type of absorption site which should be simulated, a condition which could reasonably lead to a better correspondence between in vitro and in vivo results; in practice, disruption of water layers can be easily achieved by a synthetic surfactant solution at its cri…