Search results for "focal"
showing 10 items of 803 documents
Cell-cycle control in cell-biomaterial interactions
2000
Current biocompatibility testing involves the demonstration of cell proliferation, which is usually interpreted as a sign of positive biocompatibility when the materials sustain cell proliferation. As the field of biomaterials research is rapidly moving toward tissue-engineered devices and hybrid organs, control of cell function has become a main topic. Cell function, which involves specific differentiation pathways, cannot be separated from cell-cycle control. The study of cell-cycle control is an important extension of routine proliferation assays and has extensive roots in developmental and tumor biology. We studied the expression of the tumour suppressor gene p53 and the proliferation-a…
Influencia de la instrumentación con lima única en la calidad de la obturación del sistema de conductos radiculares mediante la técnica de condensaci…
2015
1.- Introducción: el principal objetivo en la terapia endodóncica es simplificar los procedimientos con completa seguridad y eficacia. Como alternativa a los sistemas rotatorios multilima, se crearon los sistemas de lima única de rotación alternante, con el fin de reducir la fatiga cíclica para disminuir el riesgo de fractura de los instrumentos, la deformidad del conducto radicular, rapidez y simplicidad en la conformación. Posteriormente, aparecieron sistemas de lima única de rotación continua que también aumentaron la rapidez y la simplicidad. Con la finalidad de analizar la capacidad de conformar los conductos radiculares de estos sistemas endodóncicos se realizó este estudio. 2.- Objet…
Multifokālo kontaktlēcu lietotāju redzes asums un stereoredze
2018
Bakalaura darbs uzrakstīts uz 37 lapaspusēm, satur 10 zīmējumus, 5 tabulas un 18 literatūras avotus. Darba mērķis ir novērtēt redzes asumu un stereoredzi tuvumā un tālumā pacientiem koriģētiem ar brillēm un multifokālajām kontaktlēcām. Mūsu pētījumi parādīja, ka tāluma binokulārais redzes asums visiem pacientiem ir labs – virs 0,95. Tuvuma redzes asums pacientiem koriģētiem ar brillēm ir labāks un pacienti dod priekšroku brillēm. Tuvuma stereoredze noteikta ar Titmusa mušas testu un Titmusa apļu testu pacientiem koriģētiem ar brillēm un kontaktlēcām bija laba. Tāluma stereoredzes parametriem mēs redzam atšķirību, ar brillēm stereoredze ir labāka, bet rezultātu atšķirība nav statistiski būti…
Processus attentionnels et apprentissage moteur
2012
International audience; Le but de cet article est de synthétiser les travaux portant sur les effets de l’attention volontaire sur l’apprentissage d’une habileté motrice. Les premiers modèles d’apprentissage considèrent que l’apprenant franchit plusieurs étapes au cours desquelles la sollicitation des processus attentionnels diminue (Fitts & Posner, 1967). Ainsi, la réalisation d’un mouvement nécessiterait d’engager de l’attention en début d’apprentissage alors qu’elle serait automatique en fin d’apprentissage. Cet article propose de vérifier cette affirmation au regard des recherches récentes qui révèlent que l’apprenant débutant module volontairement son attention a fin d’optimiser la réal…
Novità in tema di IOL multifocali.
2008
RAB18 Loss Interferes With Lipid Droplet Catabolism and Provokes Autophagy Network Adaptations
2020
Autophagy is dependent on appropriate lipid supply for autophagosome formation. The regulation of lipid acquisition and the autophagy network response to lipid-limiting conditions are mostly elusive. Here, we show that the knockout of the RAB GTPase RAB18 interferes with lipid droplet catabolism, causing an impaired fatty acid release. The resulting reduced lipid-droplet-derived lipid availability influences autophagy and provokes adaptive modifications of the autophagy network. These adjustments include increased expression and phosphorylation of ATG2B as well as augmented formation of the ATG12-ATG5 conjugate. Moreover, ATG9A shows an enhanced phosphorylation at amino acid residues tyrosi…
Partially disarticulated new Miocene burrower bug (Hemiptera: Heteroptera: Cydnidae) from Cerová (Slovakia) documents occasional preservation of terr…
2015
The state of preservation of the bug Sehirus carpathiensis J.A. Lis, Vršanský & Schlögl, sp. n. (Hemiptera: Heteroptera: Cydnidae) from the Lakšárska Nová Ves Formation at Cerová (Slovakia) supports extremely rapid sinking and burial in upper bathyal Early Miocene sediments. The specimen originated from land at most a few kilometers away, but transport via a river can be excluded as the head and wings are still attached. Its most likely source based on fossil flora and the habitat of several living representatives of the genus is a riparian habitat in an adjacent area of land. Phylogenetically the new species is closely related to both Oligocene and living representatives of the genus, thus…
A DNA‐Encoded FRET Biosensor for Visualizing the Tension across Paxillin in Living Cells upon Shear Stress
2022
Paxillin is a potential participant in the direct intracellular force transmission which is considered as the foundation of cells sensing and responding to extracellular environment. However, the detection of tension across paxillin has not been achieved due to lacking microsized tools. Herein, a paxillin tension sensor (PaxTs) based on Fluorescence Resonance Energy Transfer (FRET) technique was constructed. PaxTs can be expressed and assembled to FA sites spontaneously to visualize the tension across paxillin with FRET efficiency of ~62.4% in living cells. The tension across paxillin was found to decrease upon shear stress, in which the membrane fluidity and contractility of actin acted as…
Characterization of a CZT focal plane small prototype for hard X-ray telescope
2005
The promise of good energy and spatial resolution coupled with high efficiency and room temperature operation has fuelled a large international effort to develop cadmium zinc telluride (CZT) for hard X-ray applications. We are involved on the development of a hard X-ray telescope based on multilayer optics and focal plane detector operative in the 10-80 keV energy range. This telescope requires a high efficiency focal plane providing both fine spatial resolution and spectroscopy with a compact and robust design. This paper reports preliminary results on the characterization both in spectroscopic and spatial response of two small pixellated CZT detectors (10times10times1 mm3 and 10times10tim…