Search results for "forensic"

showing 10 items of 1701 documents

Hemiplejía conversiva como accidente de trabajo. Consideraciones clínicas y legales

2011

Hysterical paralysis is a rare variant of conversion disorder. Its diagnostic can be difficult, and organic causes of paralysis must be ruled out. We report here a case of hysterical hemiplegia that was attributed to occupational-linked stress factors, and was consequently considered as an accident at work. Diagnostic and treatment procedures carried out in this case are reported. Compensation rates published by the Spanish Government pay little attention to occupational-linked psychiatric diseases. Frequently, as in our case, an extrapolation

medicine.medical_specialtyPsychoanalysisHysterical paralysisParalysismedicinemedicine.symptommedicine.diseasePsychiatryPsychologyConversion disorderPathology and Forensic MedicineRevista Española de Medicina Legal
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Effects of atypical antipsychotics on neurocognition in euthymic bipolar patients

2010

International audience; n.a

medicine.medical_specialtyPsychotherapistlcsh:RC435-571[SDV.MHEP.PSM] Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health3. Good health030227 psychiatry03 medical and health sciencesPsychiatry and Mental health0302 clinical medicinelcsh:PsychiatryForensic psychiatry[SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental healthMeeting AbstractmedicinePsychopharmacologyPsychiatryPsychologyNeurocognitive030217 neurology & neurosurgeryGeriatric psychiatryComputingMilieux_MISCELLANEOUS
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Utility of post mortem MRI in definition of thrombus in aneurismatic coronary arteries due to incomplete Kawasaki Disease in infants

2016

Abstract Kawasaki disease (KD) is an acute, self-limited vasculitis of unknown etiology that primarily affects the coronary artery (CA) and presents in childhood. The characteristic coronary arterial lesion is an aneurysm, which may lead to thrombosis, dilatation, stenosis, and occlusion. Such an aneurysm is typically calcified and generally develops five or more years after the onset of acute KD. It becomes more noticeable after ten years. KD is sometimes difficult to diagnose because of the limited clinical features, especially in infants younger than 6 months old, where the clinical presentations often do not fulfill the diagnostic criteria for KD. We report a case of Incomplete Kawasaki…

medicine.medical_specialtyRadiology Nuclear Medicine and Imaging2734Aneurismatic coronary arterieAutopsy030204 cardiovascular system & hematology030218 nuclear medicine & medical imagingPathology and Forensic MedicineForensic pathology03 medical and health sciences0302 clinical medicineAneurysmIncomplete Kawasaki diseaseInternal medicinemedicinePost-mortem MRIThrombusbusiness.industrymedicine.diseaseThrombosisCoronary arteriesStenosismedicine.anatomical_structureSudden infant deathThrombosiCardiologyKawasaki diseasebusinessVasculitis
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Two-Step Digital Follow-up of Patients at High Risk for Melanoma: a Retrospective Analysis of 152 Patients

2021

Antecedentes: La dermatoscopia digitalizada (DD) ha demostrado mejorar la precisión en el diagnóstico del melanoma (MM) en pacientes de alto riesgo. La combinación de DD y fotografía corporal total (FCT) puede facilitar la detección de nuevas lesiones o la aparición de cambios macroscópicos precoces en lesiones previamente registradas. Objetivos: El objetivo del presente estudio fue determinar el número de biopsias necesarias para diagnosticar un MM y, las características clínicas y dermatoscópicas asociadas al diagnóstico de melanoma en pacientes en seguimiento, mediante DD y FCT, de lesiones pigmentadas. Pacientes y métodos: Se realizó un estudio retrospectivo de 152 pacientes con elevado…

medicine.medical_specialtySkin NeoplasmsHistologyFotografía corporal totalTwo stepDermoscopyTotal-body photographyDermatologySeguimientoPathology and Forensic MedicineLesionBreslow Thickness030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineBiopsymedicineRetrospective analysisHumans030212 general & internal medicineNevus displásicoskin and connective tissue diseasesDermatoscopia digitalneoplasmsMelanomaRetrospective Studiesmedicine.diagnostic_testbusiness.industryMelanomaFollow-upMelanoma malignoRetrospective cohort studyDigital dermoscopymedicine.diseaseDermatologySpainDysplastic nevusmedicine.symptombusinessDysplastic nevusFollow-Up Studies
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Sodium Oxybate Therapy for Alcohol Withdrawal Syndrome and Keeping of Alcohol Abstinence

2018

BACKGROUND Gamma-hydroxybutyrate (GHB or sodium oxybate) is both an exogenous and endogenous molecule with neuromodulator properties. In the United States, GHB is an approved drug for the treatment of narcolepsy and narcolepsy with cataplexy in adults. In some European Union countries, sodium oxybate is applied for the treatment of opioid and alcohol withdrawal. OBJECTIVE The aim of the present review was to describe the state of art of the pre-clinical research and the clinical evidence related to GHB used alone or in combination with other treatments in alcohol withdrawal syndrome and alcohol abstinence maintenance. METHOD Internationally published pre-clinical findings and clinical studi…

medicine.medical_specialtySodium Oxybatemedia_common.quotation_subjectClinical Biochemistry01 natural sciencesNaltrexone03 medical and health sciences0302 clinical medicinemedicineHumansmedia_common.cataloged_instance030216 legal & forensic medicineEuropean unionPsychiatrymedia_commonPharmacologyAlcohol Abstinencebusiness.industry010401 analytical chemistryGamma hydroxybutyrategamma-Hydroxybutyric acidAbstinencemedicine.diseaseSubstance Withdrawal Syndrome0104 chemical sciencesAlcohol withdrawal syndromeSodium OxybatebusinessAlcohol-Related DisordersCentral Nervous System AgentsAlcohol Abstinencemedicine.drugCurrent Drug Metabolism
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A new resonant Laser-SNMS system for environmental ultra-trace analysis: Installation and optimization

2017

Abstract Localization, analysis and mobility of radioactive contaminated particles is of major concern for assessment of contamination threads and nuclear forensics. For this purpose, a new resonant Laser-SNMS system was developed and set up at the Institute for Radioecology and Radiation Protection for spatially resolved ultra-trace analysis of low concentrated radionuclides directly on environmental samples. This paper describes the adaption and combination of a dedicated Ti:sapphire laser system with a commercial TOF-SIMS instrument for resonant Laser-SNMS. The project includes computer simulations for optimization of the TOF analyzer. Results on synthetic uranium and technetium samples …

medicine.medical_specialtySpectrum analyzerNuclear forensicsNuclear engineeringchemistry.chemical_elementNanotechnology01 natural scienceslaw.inventionRadioecologylaw0103 physical sciencesmedicinePhysical and Theoretical Chemistry010306 general physicsInstrumentationSpectroscopyRadionuclideChemistrybusiness.industry010401 analytical chemistryUraniumContaminationCondensed Matter PhysicsLaser0104 chemical sciencesRadiation protectionbusinessInternational Journal of Mass Spectrometry
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Telemedicine during Covid-19 pandemic: Advantage or critical issue?

2020

Telemedicine offers a support to traditional medicine, delivering clinical services when distance is a critical factor. Although this tool does not replace a medical examination, during Covid-19 pandemic, it reduces the spread of infection and avoids the need for a patient’s visit. It is useful in the management of chronic disorders or for patients undergoing palliative treatment. The University Hospital of Palermo has applied this in cases of chronic illness caring for patients who cannot stop their treatment, such as Department of Onco-Haematology, Internal Medicine, Dermatology, etc. The Department of Legal Medicine of Palermo, in particular, is also using telemedicine to manage medico-…

medicine.medical_specialtyTelemedicinePalliative careCoronavirus disease 2019 (COVID-19)Pneumonia ViralHealth Services AccessibilityPublic health serviceBetacoronavirus03 medical and health sciences0302 clinical medicineSettore MED/43 - Medicina LegalePandemicHumansMedicine030216 legal & forensic medicine030212 general & internal medicineDisease management (health)PandemicsSARS-CoV-2business.industryCommunicationPalliative CareMedical jurisprudenceCOVID-19Disease ManagementGeneral Medicinemedicine.diseaseTelemedicineTelemedicine covid 19 clinical servicesOutpatient visitsItalyChronic DiseaseMedical emergencyCoronavirus InfectionsbusinessMedico-Legal Journal
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Short- and long-term effects of vinblastine on the rat adrenal medulla

1979

The effects of a single high dose (10mg/kg) of vinblastine (vb) sulfate (“Velbe”, Lilly) on the ultrastructure, catecholamine (CA) content and activity of CA-synthesizing enzymes of the rat adrenal medulla were studied for up to 120h after intravenous injection of the drug.

medicine.medical_specialtyTime FactorsHistologyChemical PhenomenaVinblastinePathology and Forensic MedicineInternal medicineSingle high doseEnterochromaffin CellsmedicineAnimalsCells Culturedchemistry.chemical_classificationCell BiologyMolecular medicineRatsVinblastineChemistryEnzymemedicine.anatomical_structureEndocrinologychemistryAdrenal MedullaUltrastructureCatecholamineFemaleAdrenal medullamedicine.drugCell and Tissue Research
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p53 Involvement in the control of murine hair follicle regression.

2001

p53 is a transcription factor mediating a variety of biological responses including apoptotic cell death. p53 was recently shown to control apoptosis in the hair follicle induced by ionizing radiation and chemotherapy, but its role in the apoptosis-driven physiological hair follicle regression (catagen) remains to be elucidated. Here, we show that p53 protein is strongly expressed and co-localized with apoptotic markers in the regressing hair follicle compartments during catagen. In contrast to wild-type mice, p53 knockout mice show significant retardation of catagen accompanied by significant decrease in the number of apoptotic cells in the hair matrix. Furthermore, p53 null hair follicles…

medicine.medical_specialtyTumor suppressor genemedicine.medical_treatmentDown-RegulationApoptosisBiologyPathology and Forensic MedicineTelogen effluviumMiceBcl-2-associated X proteinDownregulation and upregulationInternal medicineProto-Oncogene ProteinsmedicineAnimalsbcl-2-Associated X ProteinMice Knockoutintegumentary systemGrowth factorAlopecia areatamedicine.diseaseHair follicleCell biologyUp-RegulationMice Inbred C57BLEndocrinologymedicine.anatomical_structureInsulin-Like Growth Factor Binding Protein 3Proto-Oncogene Proteins c-bcl-2Knockout mousebiology.proteinCommentaryFemaleTumor Suppressor Protein p53Hair FollicleThe American journal of pathology
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The physiological impact of proinsulin C-peptide

1999

Abstract The proinsulin C-peptide fulfills an important function in the biosynthesis of insulin by facilitating the formation of the correct secondary and tertiary structure of the hormone. C-peptide and insulin are released in equimolar amounts to the circulation but C-peptide has generally been considered to be biologically inert. However, recent studies indicate that C-peptide administration to type 1 diabetes patients is accompanied by improved renal function, amelioration of autonomic dysfunction, stimulated tissue glucose utilization and augmented skin and muscle blood flow. The cellular mechanisms underlying these effects may be related to C-peptide's capacity to stimulate both Na + …

medicine.medical_specialtyType 1 diabetesbiologyC-peptideInsulinmedicine.medical_treatmentATPasebiology.organism_classificationmedicine.diseasePathology and Forensic Medicinechemistry.chemical_compoundEndocrinologychemistryEnosPhysiology (medical)Internal medicinemedicinebiology.proteinNa+/K+-ATPaseHormoneProinsulinPathophysiology
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