Search results for "functional"

Functional Information, Biomolecular Messages and Complexity of BioSequences and Structures

2010

In the quest for a mathematical measure able to capture and shed light on the dual notions of information and complexity in biosequences, Hazen et al. have introduced the notion of Functional Information (FI for short). It is also the result of earlier considerations and findings by Szostak and Carothers et al. Based on the experiments by Charoters et al., regarding FI in RNA binding activities, we decided to study the relation existing between FI and classic measures of complexity applied on protein-DNA interactions on a genome-wide scale. Using classic complexity measures, i.e, Shannon entropy and Kolmogorov Complexity as both estimated by data compression, we found that FI applied to pro…

Localized surface plasmon resonance in silver nanoparticles: Atomistic first-principles time-dependent density-functional theory calculations

2015

We observe using ab initio methods that localized surface plasmon resonances in icosahedral silver nanoparticles enter the asymptotic region already between diameters of 1 and 2 nm, converging close to the classical quasistatic limit around 3.4 eV. We base the observation on time-dependent density-functional theory simulations of the icosahedral silver clusters Ag$_{55}$ (1.06 nm), Ag$_{147}$ (1.60 nm), Ag$_{309}$ (2.14 nm), and Ag$_{561}$ (2.68 nm). The simulation method combines the adiabatic GLLB-SC exchange-correlation functional with real time propagation in an atomic orbital basis set using the projector-augmented wave method. The method has been implemented for the electron structure…

Application of 3D printed scavengers for improving the accuracy of single-particle inductively coupled plasma mass spectrometry analyses of silver na…

2023

The determination of silver nanoparticles (Ag NPs) with single-particle inductively coupled plasma mass spectrometry can be severely interfered with coexisting dissolved silver causing high background signals, which can lead to inaccurate quantification of NP size and particle concentration. In this paper, chemically active and reusable 3D printed scavengers are applied for highly efficient dissolved silver removal in Ag NP dispersions, allowing more accurate determination of particle concentration and size. Selective laser sintering was used for constructing the porous 3D scavengers constituting of polystyrene used as a supporting material and ion-exchange material SiliaBond Tosic acid (TA…

Nouvelles technologies et aide à la compréhension de documents techniques : Construction et expérimentation d'un simulateur de fonctionnement de grue…

2001

Reading skills are more and more required to succeed professional examination. French crane drivers are concerned with this problem. In order to help them, we have conducted a study with three main steps. First, we carried out a cognitive work analysis. Second, we test several analogical modalities of written presentations focusing on the construction of a specific simulator. Finally, two experiments are presented showing a significative effect of this simulator on the comprehension of cranes technical documentation.

Addition of Ethylene or Hydrogen to a Main-Group Metal Cluster under Mild Conditions

2015

Reaction of the tin cluster Sn8(Arinline image)4 (Arinline image=C6H2-2,6-(C6H3-2,4,6-Me3)2) with excess ethylene or dihydrogen at 25 °C/1 atmosphere yielded two new clusters that incorporated ethylene or hydrogen. The reaction with ethylene yielded Sn4(Arinline image)4(C2H2)5 that contained five ethylene moieties bridging four aryl substituted tin atoms and one tin–tin bond. Reaction with H2 produced a cyclic tin species of formula (Sn(H)Arinline image)4, which could also be synthesized by the reaction of {(Arinline image)Sn(μ-Cl)}2 with DIBAL-H. These reactions represent the first instances of direct reactions of isolable main-group clusters with ethylene or hydrogen under mild conditions…

Self-reported life-space mobility in the first year after ischemic stroke: longitudinal findings from the MOBITEC-Stroke project

2023

Abstract Background Life-space mobility is defined as the size of the area in which a person moves about within a specified period of time. Our study aimed to characterize life-space mobility, identify factors associated with its course, and detect typical trajectories in the first year after ischemic stroke. Methods MOBITEC-Stroke (ISRCTN85999967; 13/08/2020) was a cohort study with assessments performed 3, 6, 9 and 12 months after stroke onset. We applied linear mixed effects models (LMMs) with life-space mobility (Life-Space Assessment; LSA) as outcome and time point, sex, age, pre-stroke mobility limitation, stroke severity (National Institutes of Health Stroke Scale; NIHSS), modified R…

The reality of the vessel is the void within : the representional/functionalizational and socio-symbolic levels of public spatial use

2000

Missing Data in Space-time: Long Gaps Imputation Based On Functional Data Analysis

2017

High dimensional data with spatio-temporal structures are of great interest in many elds of research, but their exhibited complexity leads to practical issues when formulating statistical models. Functional data analysis through smoothing methods is a proper framework for incorporating space-time structures: extending the basic methodology to the multivariate spatio-temporal setting, we refer to Generalized Additive Models for estimating functional data taking the spatial and temporal dependences into account, and to Functional Principal Component Analysis as a classical dimension reduction technique to cope with the high dimensionality and with the number of estimated eects. Since spatial …

Detecting clusters in spatially correlated waveforms

2017

Seismic networks often record signals characterized by similar shapes that provide important information according to their geographic positions. We propose an approach to identify homogeneous clusters of seismic waves, combining analysis of waveforms with metadata and spectrogram information. In waveforms clustering, cross-correlation measures between signals may presents some limitations, so we refer to more recent contributes relating data-depth based clustering analysis. The mechanism for alignment is also an important topic of the analysis: warping (or aligning) procedures identify nuisance effects in phase variation, that, if ignored, may result in a possible loss of information and t…

Spatio-temporal Dynamical Analysis of Brain Activity during Mental Fatigue Process

2021

Mental fatigue is a common phenomenon with implicit and multidimensional properties. It brings dynamic changes of functional brain networks. However, the challenging problem of false positives appears when the connectivity is estimated by Electroencephalography (EEG). In this paper, we propose a novel framework based on spatial clustering to explore the sources of mental fatigue and functional activity changes caused by them. To suppress the false positive observations, spatial clustering is implemented in brain networks. The nodes extracted by spatial clustering are registered back to functional magnetic resonance imaging (fMRI) source space to determined the sources of mental fatigue. The…