Search results for "fusion"

showing 10 items of 4513 documents

Role of Ischemia/Reperfusion Injury in Organ Transplantation

1997

Reperfusion of oxygenated blood into previously ischemic tissue is essential to prevent the progression of cellular injury due to the decreased nutritional blood flow, i.e., the decreased delivery of oxygen and metabolic substrates, as well as the removal of harmful metabolic byproducts. However, it has become obvious that reperfusion also initiates a complex series of pathologic events that contribute to, rather than prevent, further tissue damage. Moreover, a growing body of evidence indicates that ischemia/reperfusion injury is initiated by events that occur at the level of the microcirculation. In the first part of this overview, we will delineate the major components of the microcircul…

medicine.medical_specialtybusiness.industryIschemiaBlood flowmedicine.diseasePathophysiologyOrgan transplantationMicrocirculationTissue ischemiaInternal medicineTissue damagemedicineCardiologybusinessReperfusion injury
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P1742Experimental ischemic stroke in rats induce myocardial contractile dysfunction in vivo and ex vivo and increase cardiac vulnerability to ischemi…

2017

medicine.medical_specialtybusiness.industryIschemiamedicine.diseaseIn vivoInternal medicineIschemic strokemedicineCardiologyMedical emergencyCardiology and Cardiovascular MedicinebusinessReperfusion injuryEx vivoEuropean Heart Journal
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Extremitätenperfusion beim malignen Melanom: Indikation, Technik und Ergebnisse

2008

medicine.medical_specialtybusiness.industryMelanomamedicineGeneral Medicinebusinessmedicine.diseasePerfusionSurgeryDMW - Deutsche Medizinische Wochenschrift
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Multizentrische Phase II — Studie der Arbeitsgruppe Lebermetastasen zur wöchentlichen intraarteriellen 24 h Hochdosistherapie mit 5-FU und Folinsäure…

1998

This prospective multicenter trial was performed to determine the response rate, toxicity and applicability of continuous 24 h hepatic arterial infusion of high-dose 5-FU and folinic acid. An improved response rate (60.5% in non-pretreated patients) was however associated with many systemic side-effects (340/509), mainly nausea and diarrhea. Therefore this treatment should be applied only in selected patients in specialized centers.

medicine.medical_specialtybusiness.industryNauseaGastroenterologySurgeryFolinic acidDiarrheaHepatic arterial infusionMulticenter trialInternal medicineToxicityMedicinemedicine.symptombusinessmedicine.drug
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Imaging photoplethysmography for assessment of chronic pain patients

2019

In present pilot study application of multi-spectral imaging photoplethysmography for assessment of chronic pain patients during topical skin heating test was proposed. Photoplethysmography signal was recorded at 420nm, 530nm and 810nm illumination from the skin and corresponding perfusion indexes and perfusion maps were calculated. The novel parameter-PPGflare index was introduced and compared in neuropathic patients and healthy volunteers. Preliminary results suggest that neuropathic patients exhibited significantly lower PPGflare index, and that local heating substantially change PPG waveform at heat exposed skin region. Present study emphasizes advantages of imaging photoplethysmography…

medicine.medical_specialtybusiness.industryPain assessmentPhotoplethysmogramNeuropathic painHealthy volunteersChronic painMedicineRadiologyLaser Doppler velocimetrybusinessmedicine.diseasePerfusionOptical Diagnostics and Sensing XIX: Toward Point-of-Care Diagnostics
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Study of Post-Infarction Coronary Perfusion Using Quantitative Analysis of Myocardial Echocardiography With Intravenous Injection of Contrast

2005

Introduction and objectives. After a myocardial infarction, damage to the microcirculation indicates a worse prognosis. We compared the usefulness of the quantitative analysis of myocardial contrast echocardiography with intravenous injection of contrast (MCE-iv) with intracoronary injection (MCE-ic) for analyzing coronary perfusion. Patients and method. We studied 42 patients with a first ST-elevation myocardial infarction, single-vessel disease and a patent artery (TIMI 3, stenosis 0.75) and MCE-iv (perfusion of SonoVue, singleimage capture in 1 out of each 6 cycles with trigger set at end-systole, perfusion considered normal if >0.9). Perfusion was considered abnormal if 2 or more segmen…

medicine.medical_specialtybusiness.industryPerfusion scanningGeneral Medicinemedicine.diseaseMicrocirculationStenosisText miningmedicine.anatomical_structureInternal medicinemedicineCardiologyMyocardial infarctionbusinessPerfusionTIMIArteryRevista Española de Cardiología (English Edition)
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Use of intrapleural bortezomib in myelomatous pleural effusion

2007

medicine.medical_specialtybusiness.industryPleural effusionBortezomibMedicineHematologyRadiologybusinessmedicine.diseasemedicine.drugBritish Journal of Haematology
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Dominant frequency and complexity of electrical reentrant activation during ventricular fibrillation with releasing of NO after acute local stretchin…

2013

medicine.medical_specialtybusiness.industryRabbit heartCardiac arrhythmiaDominant frequencymedicine.diseaseReentrancyInternal medicineVentricular fibrillationCardiologymedicineMyocyteCardiology and Cardiovascular MedicinebusinessPerfusionInotropic agentEuropean Heart Journal
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Ranolazine induced modifications of ventricular fibrillation activation complexity under mechanical stretch

2013

medicine.medical_specialtybusiness.industryRanolazineCardiac arrhythmiamedicine.diseasemedicine.anatomical_structureInternal medicineVentricular fibrillationCardiologyMyocyteMedicineAtrium (heart)Cardiology and Cardiovascular MedicinebusinessPerfusionmedicine.drugEuropean Heart Journal
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Effect of Streptomycin on Stretch-Induced Change in Myocardial Activation During Ventricular Fibrillation

2008

The aim of this study was to determine whether the changes in myocardial activation pattern resulting from acute stretching during ventricular fibrillation can be counteracted by administering a compound that blocks receptors sensitive to stretch. The study involved 16 isolated rabbit hearts, in which refractoriness and activation frequency during ventricular fibrillation were measured before, during and after localized acute stretching of the left ventricular free wall, either without (series A, n=8) or with (series B, n=8) the presence of streptomycin, 200 micromol. At baseline and during and after stretching, ventricular fibrillation was slower with streptomycin perfusion in series B tha…

medicine.medical_specialtybusiness.industryRefractory periodHeartGeneral MedicineIn Vitro Techniquesmedicine.diseaseActivation patternFree wallElectrophysiologyStreptomycinInternal medicineVentricular FibrillationVentricular fibrillationStreptomycinmedicineCardiologyAnimalsHumansRabbitsReceptorbusinessPerfusionmedicine.drugRevista Española de Cardiología (English Edition)
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