Search results for "g factor"

Pathogen safety of long-term treatments for bleeding disorders: still relevant to current practice

2013

Hemophilia defines a group of hereditary bleeding disorders: hemophilia A (deficiency of Factor VIII, FVIII), hemophilia B (deficiency of FIX), and para-hemophilia (deficiency of FV). These result from mutations in clotting factor genes. As in the large majority of bleeding disorders ([Table 1][1

Modelowanie potęgi państwa - wybrane zagadnienia

2018

W artykule przedstawiono zagadnienia związane z modelowaniem potęgi państwa. Dokonano przeglądu najważniejszych modeli potęgi państwa, wraz z charakterystyką poszczególnych składowych. Opisano rożne ujęcia potęgi, w ramach wybranych teorii stosunków międzynarodowych

Analiza rozwoju wybranych czynników potęgotwórczych państw Grupy Wyszehradzkiej w obszarze społeczno-gospodarczym

2018

W artykule przedstawiono zagadnienia dotyczące istoty określania potęgi państwa i jej kluczowych komponentów. Wskazano szczegółowe wskaźniki, mieszczące się w ramach poszczególnych wymiarów potęgi państwa. Opisano rozwój wskaźnika wolności gospodarczej i demokracji w państwach Grupy Wyszehradzkiej, na przestrzeni ostatniej dekady. Wyniki analizy porównawczej zobrazowano w formie graficznej.

Seasonal changes of cambial activity in seed plants in relation to climatic zones

2016

Oxytocin Signaling as a Target to Block Social Defeat-Induced Increases in Drug Abuse Reward

2021

There is huge scientific interest in the neuropeptide oxytocin (OXT) due to its putative capacity to modulate a wide spectrum of physiological and cognitive processes including motivation, learning, emotion, and the stress response. The present review seeks to increase the understanding of the role of OXT in an individual’s vulnerability or resilience with regard to developing a substance use disorder. It places specific attention on the role of social stress as a risk factor of addiction, and explores the hypothesis that OXT constitutes a homeostatic response to stress that buffers against its negative impact. For this purpose, the review summarizes preclinical and clinical literature rega…

Managerial career plateaue : determinants, consequences and coping strategies

2008

Masteroppgave i økonomi og administrasjon - Universitetet i Agder 2008 During last decade managers who were practicing in different industries in Sri Lanka, have struggled with having less promotional opportunities. This initially leads them to become plateaued with their career. This study applied the theory from career management literature to examine factors significantly influenced to employees’ perception of being subjectively plateaued and objectively plateaued. Additionally, this study aims to identify the relationship between career plateauing and its implication toward job satisfaction, organizational commitment, intention to quit and job induced stress. Further, coping strategies …

Inflammation and impaired endothelium-dependant vasodilatation in non obese women with gestational diabetes mellitus: preliminary results

2013

International audience; BACKGROUND: To evaluate whether abnormal endothelial function, a common finding in gestational diabetes mellitus (GDM) pregnancies, can be explained by inflammatory cytokines. METHODS: Forearm skin blood flow (FSBF), into response to acetylcholine (Ach) (endothelium-dependent vasodilatation), were measured in 24 pregnant control subjects and 28 gestational diabetes mellitus (GDM) women, in the third trimester of gestation. A fasting glycemic and lipidic panel was obtained, and inflammatory cytokines (TNF-alpha and IL-6) and adiponectin were also determined. RESULTS: FSBF is significantly reduced in GDM group compared with control subjects (344.59 +/- 57.791 vs.176.38…

Absence of mutations in the WT1 gene in patients with XY gonadal dysgenesis

1995

The WT1 gene is normally expressed during gonadal development and specific mutations in heterozygous form cause Drash syndrome, characterized by male pseudohermaphroditism and gonadal dysgenesis, renal failure and a predisposition for Wilms' tumour. These observations prompted us to test whether WT1 mutations are involved in isolated gonadal dysgenesis, being the most severe form of disturbance in gonadal differentiation. We studied 27 cases of 46,XY females with gonadal dysgenesis who had previously been screened for and found not to carry SRY gene mutations. We performed mutational screening of the WT1 gene with denaturing gradient gel electrophoresis. In one of these patients, a heterozy…

What hampers green product innovation: the effect of experience

2019

Based on representative firm-level survey data for Austria, Germany, and Switzerland, this study systematically analyzes the relevance and drivers of barriers to green product innovation using the example of green energy technologies. “Low willingness to pay”, “high development costs”, “high commercial uncertainty”, and “lack of favorable political framework” are identified as the most important barriers. Moreover, we find that the firms’ innovation experience is an important driver of the level of green innovation barriers. Green innovation barriers are more accentuated for firms with green innovation activity than for firms with no green innovation activity. However, experience from diffe…

EXTRACURRICULAR ACTIVITIES AND THEIR INFLUENCE ON UNIVERSITY'S ATTRACTIVENESS

2015

This paper aims to determine the respondents' opinion regarding the extracurricular activities within their universities and to establish the influencing factors on the university's attractiveness. This study has been elaborated based on the quantitative research, through primary research and the data is gathered through the questionnaire method. The research has been developed within the "Lucian Blaga" University of Sibiu, Politehnica University Timișoara, Babeș Bolyai University Cluj, Bucharest University of Economic Studies and Politehnica University Bucharest and 728 students have been questioned in the period June - September 2014. As a result of the analysis, an influence of the extra…