Search results for "genes"

showing 10 items of 13944 documents

Ultrastructure of regions containing homologous loci in polytene chromosomes of Drosophila melanogaster and Drosophila subobscura.

1998

We have used a new approach involving in situ hybridisation and electron microscopy to establish ultrastructural homologies between polytene chromosome regions of Drosophila melanogaster and Drosophila subobscura. Twelve probes were chosen to cover all the chromosomal elements: the myospheroid gene, the collagen type IV gene, the collagen-like gene, the w26 homeobox gene, the beta3 tubulin gene, the kinesin heavy chain gene, the tryptophan hydrolase gene, the Hsp82, Hsp22-26 and Hsp23-28, Hsp68, Hsp70 genes and the beta unit of the F0-F1 ATPase gene. Most of these loci were previously undescribed in D. subobscura and imprecisely located in D. melanogaster. We have demonstrated here, by an u…

0106 biological sciencesIntegrinsHSP30 Heat-Shock ProteinsKinesinsMuscle ProteinsLocus (genetics)Genes InsectTryptophan Hydroxylase010603 evolutionary biology01 natural sciencesHomology (biology)Chromosomes03 medical and health sciencesTubulinSequence Homology Nucleic AcidGeneticsMelanogasterAnimalsDrosophila ProteinsHSP20 Heat-Shock ProteinsHSP70 Heat-Shock ProteinsGeneGenetics (clinical)Heat-Shock Proteins030304 developmental biologyGenetics0303 health sciencesPolytene chromosomebiologyMembrane Proteinsbiology.organism_classificationDrosophila subobscuraChromosome BandingProton-Translocating ATPasesDrosophila melanogasterChromosomal regionCollagenDrosophila melanogasterDNA ProbesIntegrin alpha ChainsChromosoma
researchProduct

CRISPR-mediated strand displacement logic circuits with toehold-free DNA

2021

DNA nanotechnology, and DNA computing in particular, has grown extensively over the past decade to end with a variety of functional stable structures and dynamic circuits. However, the use as designer elements of regular DNA pieces, perfectly complementary double strands, has remained elusive. Here, we report the exploitation of CRISPR-Cas systems to engineer logic circuits based on isothermal strand displacement that perform with toehold-free double-stranded DNA. We designed and implemented molecular converters for signal detection and amplification, showing good interoperability between enzymatic and nonenzymatic processes. Overall, these results contribute to enlarge the repertoire of su…

0106 biological sciencesLetterTranscription GeneticComputer scienceStreptococcus pyogenesRibonuclease HBiomedical EngineeringDNA Single-StrandedNanotechnology01 natural sciencesBiochemistry Genetics and Molecular Biology (miscellaneous)Displacement (vector)law.invention03 medical and health sciencesSynthetic biologychemistry.chemical_compoundComputers MolecularDNA computinglaw010608 biotechnologyCRISPR-Associated Protein 9Biological computingDNA nanotechnologyCRISPRNanotechnologyClustered Regularly Interspaced Short Palindromic RepeatsGene Regulatory NetworksDNA nanotechnologySynthetic biology030304 developmental biologyElectronic circuit0303 health sciencesGeneral MedicineRibonuclease PancreaticchemistryLogic gatebiological computingsynthetic biologyCRISPR-Cas SystemsEndopeptidase KGenetic EngineeringDNARNA Guide Kinetoplastida
researchProduct

Artemisia arborescens essential oil composition, enantiomeric distribution and antimicrobial activity from different wild populations from the Medite…

2016

International audience; Aerial parts of Artemisiaarborescens were collected from different sites of the Mediterranean area (southwestern Algeria and southern Italy) and the chemical composition of their essential oil (EO) extracted by hydrodistillation was studied by both gas chromatography (GC) equipped with an enantioselective capillary column and GC/mass spectrometry (GC/MS). The EOs obtained were tested against several Listeriamonocytogenes strains. Using GC and GC/MS, 41 compounds were identified, accounting for 96.0-98.8% of the total EO. All EOs showed a similar terpene profile, which was rich in chamazulene, -thujone, and camphor. However, the concentration of such compounds varied …

0106 biological sciencesListeriaBioengineeringMicrobial Sensitivity TestsSettore MED/42 - Igiene Generale E Applicata01 natural sciencesBiochemistry[ CHIM ] Chemical Scienceslaw.inventionTerpeneCamphorchemistry.chemical_compoundlawBotanyOils Volatile[CHIM]Chemical SciencesFood scienceMolecular BiologyEssential oilVolatile compositionbiologyChemotypeMediterranean RegionChemistryChamazuleneBiological activityStereoisomerismGeneral ChemistryGeneral Medicinebiology.organism_classificationArtemisia arborescensEnantiomeric distributionListeria monocytogenesAnti-Bacterial Agents0104 chemical sciences010404 medicinal & biomolecular chemistrySettore MED/18 - Chirurgia GeneraleArtemisiaItalyAlgeriaGram-negative bacteriaMolecular MedicineArtemisiaGas chromatographyEnantiomeric distribution Biological activity Gram-negative bacteria Volatile composition Listeria monocytogenes.010606 plant biology & botanySettore AGR/16 - Microbiologia Agraria
researchProduct

Diversifying selection on MHC class I in the house sparrow (Passer domesticus).

2009

10 pages; International audience; Genes of the major histocompatibility complex (MHC) are the most polymorphic loci known in vertebrates. Two main hypotheses have been put forward to explain the maintenance of MHC diversity: pathogen-mediated selection and MHC-based mate choice. Host-parasite interactions can maintain MHC diversity via frequency-dependent selection, heterozygote advantage, and diversifying selection (spatially and/or temporally heterogeneous selection). In this study, we wished to investigate the nature of selection acting on the MHC class I across spatially structured populations of house sparrows (Passer domesticus) in France. To infer the nature of the selection, we comp…

0106 biological sciencesMESH : Gene FlowMESH: Selection (Genetics)MESH: GeographyGenes MHC Class IMESH: Genetic MarkersBalancing selectionMESH : Microsatellite Repeats[ SDV.IMM.IA ] Life Sciences [q-bio]/Immunology/Adaptive immunology01 natural sciencesmicrosatellitesMESH: SparrowsMESH : Genetic MarkersMESH: AnimalsMESH: Genetic VariationMESH: Evolution MolecularGenetics0303 health scienceseducation.field_of_studyGeographybiology[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]MESH : GeographyMESH: Genes MHC Class I[ SDE.MCG ] Environmental Sciences/Global Changes[ SDV.BID.EVO ] Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE][SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunologyMate choiceMESH: Stochastic ProcessesMHC class IMESH : MutationSparrowsGene FlowGenetic MarkersMESH: Mutationbalancing selection[SDE.MCG]Environmental Sciences/Global ChangesPopulationMESH : Genetic DriftMESH: Genetics Populationchemical and pharmacologic phenomenaMESH : Stochastic ProcessesMajor histocompatibility complex010603 evolutionary biologyMESH : Genes MHC Class IEvolution Molecular03 medical and health sciencesMESH : Genetic VariationMHC class IGeneticsPasser domesticusMESH : Selection (Genetics)AnimalsMESH : Evolution MolecularSelection GeneticMESH: Genetic DrifteducationAllelesMESH: Gene FlowEcology Evolution Behavior and SystematicsSelection (genetic algorithm)030304 developmental biologyLocal adaptationIsolation by distanceStochastic Processes[ SDE.BE ] Environmental Sciences/Biodiversity and Ecologyhouse sparrowMESH: AllelesGenetic DriftGenetic Variationdiversifying selectionPasser domesticus.[ SDV.GEN.GA ] Life Sciences [q-bio]/Genetics/Animal geneticsMESH : Genetics Population[SDE.ES]Environmental Sciences/Environmental and Society[SDV.GEN.GA]Life Sciences [q-bio]/Genetics/Animal geneticsGenetics PopulationEvolutionary biologyMutationbiology.proteinMESH: Microsatellite RepeatsMESH : AnimalsMESH : Sparrows[SDE.BE]Environmental Sciences/Biodiversity and EcologyMESH : Alleles[ SDE.ES ] Environmental Sciences/Environmental and SocietyMicrosatellite Repeats
researchProduct

The Chlamydomonas genome reveals the evolution of key animal and plant functions

2007

Chlamydomonas reinhardtii is a unicellular green alga whose lineage diverged from land plants over 1 billion years ago. It is a model system for studying chloroplast-based photosynthesis, as well as the structure, assembly, and function of eukaryotic flagella (cilia), which were inherited from the common ancestor of plants and animals, but lost in land plants. We sequenced the ∼120-megabase nuclear genome of Chlamydomonas and performed comparative phylogenomic analyses, identifying genes encoding uncharacterized proteins that are likely associated with the function and biogenesis of chloroplasts or eukaryotic flagella. Analyses of the Chlamydomonas genome advance our understanding of the a…

0106 biological sciencesMESH: Sequence Analysis DNAMESH: Algal ProteinsChloroplastsProteomeMESH: PlantsChlamydomonas reinhardtii01 natural sciencesGenomeMESH: Membrane Transport ProteinsDNA AlgalMESH: DNA AlgalMESH: AnimalsGoniumPhotosynthesisMESH: PhylogenyMESH: PhotosynthesisPhylogenyGenetics0303 health sciencesGenomeMultidisciplinarybiologyMESH: Genomicsfood and beveragesGenomicsPlantsBiological EvolutionMESH: Genes[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biomolecules [q-bio.BM]MESH: ProteomeFlagellaMultigene FamilyMESH: Computational BiologyMESH: Chlamydomonas reinhardtiiNuclear geneMolecular Sequence Data[SDV.BC]Life Sciences [q-bio]/Cellular BiologyFlagellumMESH: FlagellaArticle03 medical and health sciencesIntraflagellar transportMESH: EvolutionAnimalsMESH: Genome[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biochemistry [q-bio.BM]Gene[SDV.BC] Life Sciences [q-bio]/Cellular Biology030304 developmental biologyMESH: Molecular Sequence DataMESH: ChloroplastsAlgal ProteinsChlamydomonasComputational BiologyMembrane Transport ProteinsSequence Analysis DNAbiology.organism_classificationGenesMESH: Multigene FamilyChlamydomonas reinhardtii010606 plant biology & botany
researchProduct

Paternal age negatively affects sperm production of the progeny.

2021

International audience; Parental age has profound consequences for offspring’s phenotype. However, whether patrilineal age affects offspring sperm production remains unknown, despite the importance of sperm production for male reproductive success in species facing post-copulatory sexual selection. Using a longitudinal dataset on ejaculate attributes of the houbara bustard, we showed that offspring sired by old fathers had different age-dependent trajectories of sperm production compared to offspring sired by young fathers. Specifically, they produced less sperm (−48%) in their first year of life, and 14% less during their lifetime. Paternal age had the strongest effect, with weak evidence …

0106 biological sciencesMaleAgingOffspring010603 evolutionary biology01 natural sciencesPaternal Age[SDV.BDLR.RS]Life Sciences [q-bio]/Reproductive Biology/Sexual reproductionejaculate qualityBirdsReproductive senescencereproductive senescence[SDV.BA.ZV]Life Sciences [q-bio]/Animal biology/Vertebrate ZoologyAnimalsBustardEcology Evolution Behavior and Systematicsreproductive and urinary physiologybiologyReproductive successEcology010604 marine biology & hydrobiologyReproductionbiology.organism_classificationSpermSpermatozoamale gametesAgeingSexual selectionpost copulatory sexual selectionSpermatogenesisDemographyoffspring phenotypeEcology lettersReferences
researchProduct

Transfer of individuals as a means of investigating natural selection in operation.

2009

Populations of Philaenus spumarius (Homoptera) displaying colour polymorphism at stable equilibrium were subjected to the introduction of alien phenotypes. In an exchange experiment between populations of isolated islands, 2/3 of population A, from Allgrundet, was transferred to Porskobben, and 2/3 of population P from Porskobben to Allgrundet. The immediate result of the transfer was A-type allele frequencies on Porskobben and P-type frequencies on Allgrundet. After four generations, the pre-transfer frequencies were almost completely restored. This change implies strong island-specific selection pressures. The process was remarkably rapid in view of the mixed composition of the gene pools…

0106 biological sciencesMaleHomopteraPopulationPhilaenus spumariusZoology010603 evolutionary biology01 natural sciencesHemiptera03 medical and health sciencesTransformation GeneticGene FrequencyGeneticsAnimalsSelection GeneticeducationAllele frequencySelection (genetic algorithm)Alleles030304 developmental biology0303 health scienceseducation.field_of_studyNatural selectionPolymorphism GeneticbiologyEcologyPopulation sizeGeneral Medicinebiology.organism_classificationPhenotypeGenesFemaleGene poolHereditas
researchProduct

Effect of gender on physiological and behavioural responses of Gammarus roeseli (Crustacea Amphipoda) to salinity and temperature.

2010

8 pages; International audience; The importance of potentially interacting factors in organisms responses to a stress are often ignored or underestimated in ecotoxicology. In laboratory experiments we investigated how gender, temperature and age influence the behaviour and the physiology of the freshwater amphipod Gammarus roeseli under salinity stress. Our results revealed a significant higher sensitivity of females in survival, ventilation and ionoregulation whereas no inter-age differences were reported. Water temperature also exerted a significant effect in survival and ventilation of G. roeseli. Some of those factors appeared to interact significantly. This study provides evidence that…

0106 biological sciencesMaleSalinityAmphipodaPhysiologyHealth Toxicology and Mutagenesis010501 environmental sciencesSodium ChlorideToxicologymedicine.disease_cause01 natural sciences[ SDV.EE ] Life Sciences [q-bio]/Ecology environment[SDV.EE.ECO]Life Sciences [q-bio]/Ecology environment/EcosystemsSalinity stressSpecies SpecificityGender effectGammarus roeselimedicineEcotoxicologyAnimalsAmphipodaBehaviourComputingMilieux_MISCELLANEOUSGammarus roeseli0105 earth and related environmental sciences[SDV.EE]Life Sciences [q-bio]/Ecology environment[ SDE.BE ] Environmental Sciences/Biodiversity and EcologybiologyBehavior AnimalEcology010604 marine biology & hydrobiologyStressorEnvironmental factorTemperatureGeneral Medicinebiology.organism_classificationPollutionCrustacean6. Clean waterSalinityBreathingFemale[SDV.TOX.ECO]Life Sciences [q-bio]/Toxicology/Ecotoxicology[SDE.BE]Environmental Sciences/Biodiversity and Ecology[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
researchProduct

Fishery-induced selection for slow somatic growth in European eel

2012

International audience; Both theoretical and experimental studies have shown that fishing mortality can induce adaptive responses in body growth rates of fishes in the opposite direction of natural selection. We compared body growth rates in European eel (Anguilla anguilla) from three Mediterranean stocks subject to different fishing pressure. Results are consistent with the hypotheses that i) fast-growing individuals are more likely to survive until sexual maturity than slow-growing ones under natural conditions (no fishing) and ii) fishing can select for slow-growing individuals by removing fast-growing ones. Although the possibility of human-induced evolution seems remote for a panmictic…

0106 biological sciencesMale[SDV]Life Sciences [q-bio]lcsh:MedicineMarine and Aquatic Sciences01 natural sciencesKeyWords Plus:FRESH-WATER ENVIRONMENTS; ANGUILLA-ANGUILLA L; SEX-DIFFERENTIATION; MORTALITY; LAGOONS; POPULATION; MATURATION; JUVENILE; BRACKISH; TRAITSCritically endangeredAUTMorphogenesisNatural SelectionSexual maturityBody SizeScopus Indexed keywords EMTREE medical terms: Anguilla (fish)article body growth controlled study eel endangered species experimental study fishery fishing growth rate mortality natural selection nonhuman theoretical study Anguilla (fish)animal body size female food industry growth development and aging male physiology reproduction Species Index: Anguilla anguilla Pisces MeSH: Anguilla Animals Body Size Female Fisheries Male Reproductionlcsh:ScienceJUVENILEPOPULATIONmedia_commonFreshwater EcologyPanmixiaMultidisciplinaryNatural selectionEcologyEcologyReproduction[SDE]Environmental SciencesFish <Actinopterygii>FemaleReproductionCoastal EcologyTRAITSResearch ArticleKeyWords Plus:FRESH-WATER ENVIRONMENTSEvolutionary ProcessesFRESH-WATER ENVIRONMENTSSettore BIO/07media_common.quotation_subjectFishingFisheriesMarine BiologyLAGOONSBiology010603 evolutionary biologyMATURATIONBRACKISHANGUILLA-ANGUILLA LAnimals14. Life underwaterBiologySelection (genetic algorithm)Growth ControlEvolutionary BiologySEX-DIFFERENTIATION010604 marine biology & hydrobiologyMORTALITYlcsh:RFisheries ScienceAnguillaFisheryEvolutionary EcologyEarth SciencesFRESH-WATER ENVIRONMENTS;ANGUILLA-ANGUILLA L;SEX-DIFFERENTIATION;MORTALITY;LAGOONS;POPULATION;MATURATION;JUVENILE;BRACKISH;TRAITSlcsh:QZoologyDevelopmental Biology
researchProduct

Carvacrol activated biopolymeric foam: An effective packaging system to control the development of spoilage and pathogenic bacteria on sliced pumpkin…

2021

Abstract A commercial biodegradable starch-based polymer (Mater-Bi) was activated with carvacrol to develop a biodegradable and compostable polymer to be used in food packaging. Based on previous tests, carvacrol was added at 20 % weight of foam. MB foams, with and without carvacrol, were tested for their morphological characteristics, mechanical tests and kinetics of carvacrol release under refrigerated storage conditions. Carvacrol slightly increased the porosity of the foams, induced a reduction of the compressive elastic modulus (Ecom) of foamed MB from 6 to ∼ 3.4 MPa and a decrease of the tensile elastic modulus from ∼70 MPa to ∼16.5 MPa. Carvacrol release from the foam at 4 °C was alm…

0106 biological sciencesMicrobiology (medical)Polymers and PlasticsMelonStarchFood spoilageActive packagingBiopolymeric foamsSettore AGR/04 - Orticoltura E FloricolturaSpoilage and pathogenic bacteriamedicine.disease_cause01 natural sciencesAntibacterial propertiesBiomaterialsFood packagingchemistry.chemical_compound0404 agricultural biotechnologyListeria monocytogenesCarvacrol010608 biotechnologymedicineCarvacrolFood scienceSafety Risk Reliability and QualityFood model systemsbiologyChemistrySettore ING-IND/34 - Bioingegneria Industriale04 agricultural and veterinary sciencesbiology.organism_classification040401 food scienceFood packagingSettore ING-IND/22 - Scienza E Tecnologia Dei MaterialiIn vivo activityBacteriaSettore AGR/16 - Microbiologia AgrariaFood ScienceFood Packaging and Shelf Life
researchProduct