Search results for "genetic diversity"

showing 10 items of 449 documents

Genetic analysis of populations of brown trout (Salmo truttaL.) from the Romanian Carpathians

2019

The Carpathian Mountains are one of the most complex orogenetic areas of Europe, with unique fauna, including the brown trout (Salmo trutta). In this study we performed population genetic analysis of 12 differentS. truttapopulations using two types of molecular markers: nine microsatellites and mitochondrial D-loop sequences. The following working hypothesis was considered: the Romanian Carpathians and their surrounding lowlands can be key relief units based on which theS. truttagenetic diversity, spread, distribution, connectivity, relative isolation and genetic divergence can be at least partially explained. The phylogenetic analysis revealed that the majority of sequences were grouped in…

0106 biological scienceseducation.field_of_studyGenetic diversityPhylogenetic treebiology010604 marine biology & hydrobiologyPopulationZoologyAquatic Sciencebiology.organism_classification010603 evolutionary biology01 natural sciencesNucleotide diversityGenetic divergenceBrown troutSalmoeducationInbreedingAquatic Living Resources
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A haplotype-resolved, de novo genome assembly for the wood tiger moth (Arctia plantaginis) through trio binning

2020

ABSTRACT Background Diploid genome assembly is typically impeded by heterozygosity because it introduces errors when haplotypes are collapsed into a consensus sequence. Trio binning offers an innovative solution that exploits heterozygosity for assembly. Short, parental reads are used to assign parental origin to long reads from their F1 offspring before assembly, enabling complete haplotype resolution. Trio binning could therefore provide an effective strategy for assembling highly heterozygous genomes, which are traditionally problematic, such as insect genomes. This includes the wood tiger moth (Arctia plantaginis), which is an evolutionary study system for warning colour polymorphism. F…

0106 biological scienceshaplotypepopulation genomicsAcademicSubjects/SCI02254PopulationSequence assemblyHealth Informaticswood tiger moth; Arctia plantaginisMothsBiologyData Notegenotyyppi010603 evolutionary biology01 natural sciencesGenometäpläsiilikäsPopulation genomicsLoss of heterozygosity03 medical and health sciencesConsensus sequenceAnimalsHumanseducation030304 developmental biology0303 health scienceseducation.field_of_studyGenetic diversityGenometrio binningHaplotypewood tiger mothKaryotypegenomiikkaGenomicsWoodComputer Science ApplicationsLepidopteraHaplotypesannotationpopulaatiogenetiikkaEvolutionary biologyperimägenome assemblyAcademicSubjects/SCI00960Corrigendum
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Role of host genetic diversity for susceptibility-to-infection in the evolution of virulence of a plant virus

2019

Predicting viral emergence is difficult due to the stochastic nature of the underlying processes and the many factors that govern pathogen evolution. Environmental factors affecting the host, the pathogen and the interaction between both are key in emergence. In particular, infectious disease dynamics are affected by spatiotemporal heterogeneity in their environments. A broad knowledge of these factors will allow better estimating where and when viral emergence is more likely to occur. Here, we investigate how the population structure for susceptibility-to-infection genes of the plant Arabidopsis thaliana shapes the evolution of Turnip mosaic virus (TuMV). For doing so we have evolved TuMV …

0106 biological sciencesinfection matrixPopulationPotyvirusVirulenceMetapopulation010603 evolutionary biology01 natural sciencesMicrobiology03 medical and health sciencesVirologyPlant virusTurnip mosaic virusResistance to infectionexperimental evolutioneducationPathogenhost population structure030304 developmental biologyvirus evolution0303 health sciencesExperimental evolutioneducation.field_of_studyGenetic diversitybiologyEcotypeGenetic heterogeneityEvolution of virulenceHost population structureresistance to infectionbiology.organism_classificationInfection matrixVirus evolutionExperimental evolutionInfectious disease (medical specialty)Evolutionary biologyViral evolutionResearch Articleevolution of virulence
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A population genomics analysis of the native Irish Galway sheep breed.

2019

SUMMARYThe Galway sheep population is the only native Irish sheep breed and represents an important livestock genetic resource, which is currently categorised as “at-risk”. In the present study, comparative population genomics analyses of Galway sheep and other sheep populations of European origin were used to investigate the microevolution and recent genetic history of the breed. These analyses support the hypothesis that British Leicester sheep were used in the formation of the Galway breed and suggest more recent gene flow from the Suffolk sheep breed. When compared to conventional and endangered breeds, the Galway breed was intermediate in effective population size, genomic inbreeding a…

0301 basic medicine0106 biological sciencesAnimal breedingLivestocklcsh:QH426-470Populationbiology.animal_breedselection signaturePopulation geneticsZoologyinbreedingRuns of HomozygosityBiology010603 evolutionary biology01 natural sciencesGenetic diversityPopulation genomics03 medical and health sciences0302 clinical medicineEffective population sizesingle nucleotide polymorphismGeneticsInbreedingeducationGenetics (clinical)030304 developmental biologyOriginal Research2. Zero hunger0303 health scienceseducation.field_of_studybusiness.industryAt-risk breedat-risk breedgenetic diversitySelection signatureBreedSingle nucleotide polymorphismlivestocklcsh:Genetics030104 developmental biologyconservation genomics030220 oncology & carcinogenesisConservation genomicsSuffolk sheepMolecular MedicineLivestockFaculty of Science & Health AITbusinessInbreeding
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Long live the alien: is high genetic diversity a pivotal aspect of crested porcupine (Hystrix cristata) long-lasting and successful invasion?

2016

AbstractStudying the evolutionary dynamics of an alien species surviving and continuing to expand after several generations can provide fundamental information on the relevant features of clearly successful invasions. Here, we tackle this task by investigating the dynamics of the genetic diversity in invasive crested porcupine (Hystrix cristata) populations, introduced to Italy about 1500 years ago, which are still growing in size, distribution range and ecological niche. Using genome-wide RAD markers, we describe the structure of the genetic diversity and the demographic dynamics of theH. cristatainvasive populations and compare their genetic diversity with that of native African populatio…

0301 basic medicine0106 biological sciences[SDV]Life Sciences [q-bio]01 natural sciencesInvasive speciesgene surfingGene flowinvasive speciesSouth AfricaAfrica Northernpopulation dynamicsNorthern0303 health sciencesbiologyEcologyEcologyPhylogeographyItalyInbreedingGenetic MarkersSettore BIO/05EvolutionPopulationinbreedingAlienRAD sequencing010603 evolutionary biologyHystrix cristatagene surfing; inbreeding; invasive species; population dynamics; RAD sequencing; Africa Northern; Animals; Genetic Markers; Italy; Phylogeography; Porcupines; South Africa; Genetic Variation; Genetics Population; Introduced Species; Ecology Evolution Behavior and Systematics; Genetics03 medical and health sciencesBehavior and Systematicsbiology.animalGeneticsAnimalsEvolutionary dynamicsEcology Evolution Behavior and Systematics030304 developmental biologyEcological nicheGenetic diversityAmbientaleGenetic Variation15. Life on landPorcupinesbiology.organism_classificationPhylogeographyGenetics Population030104 developmental biologyAfricaIntroduced SpeciesPorcupinehuman activities
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Effect of Host Species on Topography of the Fitness Landscape for a Plant RNA Virus

2016

[EN] Adaptive fitness landscapes are a fundamental concept in evolutionary biology that relate the genotype of individuals with their fitness. At the end, the evolutionary fate of evolving populations depends on the topography of the landscape, that is, the number of accessible mutational pathways and of possible fitness peaks (i.e, adaptive solutions). For long time, fitness landscapes were only theoretical constructions due to a lack of precise information on the mapping between genotypes and phenotypes. In recent years, however, efforts have been devoted to characterize the properties of empirical fitness landscapes for individual proteins or for microbes adapting to artificial environme…

0301 basic medicine2. Zero hungerbiologyFitness landscapeEcologyHost (biology)ImmunologyRNA virusbiology.organism_classificationMicrobiology03 medical and health sciences030104 developmental biologyGenetic Diversity and EvolutionVirologyInsect ScienceRegional scienceEuropean commissionChristian ministryadaptive fitness landscapes ; experimental evolution ; virus evolutionJournal of Virology
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Assessment of the Antimicrobial Activity and the Entomocidal Potential of Bacillus thuringiensis Isolates from Algeria.

2017

This work represents the first initiative to analyze the distribution of B. thuringiensis in Algeria and to evaluate the biological potential of the isolates. A total of 157 isolates were recovered, with at least one isolate in 94.4% of the samples. The highest Bt index was found in samples from rhizospheric soil (0.48) and from the Mediterranean area (0.44). Most isolates showed antifungal activity (98.5%), in contrast to the few that had antibacterial activity (29.9%). A high genetic diversity was made evident by the finding of many different crystal shapes and various combinations of shapes within a single isolate (in 58.4% of the isolates). Also, over 50% of the isolates harbored cry1, …

0301 basic medicineAntifungalStaphylococcus aureusmedicine.drug_classHealth Toxicology and Mutagenesis030106 microbiologyBacterial ToxinsBiological pest controlBacillus thuringiensisBiologyToxicologyArticleMicrobiology03 medical and health sciencesB. thuringiensisAnti-Infective AgentsBacterial ProteinsBacillus thuringiensismedicineEscherichia colibiocontrolGeneSoil MicrobiologyGenetic diversitycryChitinasesFungi<i>B. thuringiensis</i>; antibacterial; antifungal; <i>cry</i>; <i>vip3</i>; chitinase; biocontrolAntimicrobialbiology.organism_classificationCryptochromesantibacterialHexosaminidasesGenes BacterialAlgeriachitinaseChitinasePseudomonas aeruginosavip3biology.proteinMicroscopy Electron ScanningAntibacterial activityantifungalToxins
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Assembly rules of helminth parasite communities in grey mullets: combining components of diversity.

2020

Abstract Organisms aggregate in ecological communities. It has been widely debated whether these associations are explained by deterministic or, in contrast, random processes. The answer may vary, depending on the level of an organisational scale (α, β and γ) and the facet of diversity considered: taxonomic, functional and phylogenetic. Diversity at the level of a sampling unit (i.e. host individual) is the α diversity; β diversity represents the extent of dissimilarity in diversity among sampling units (within a level of an organisational scale, β1; between levels of an organisational scale, β2); and the total diversity of a system is γ diversity. Thus, the combination of facets and levels…

0301 basic medicineAssembly rules030231 tropical medicineBiology03 medical and health sciencesFunctional diversity0302 clinical medicineLimiting similarityHelminthsMediterranean SeaHelminthsParasite hostingAnimals[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology14. Life underwaterPhylogenyPhylogenetic treeEcologyrespiratory systemSmegmamorphaPhylogenetic diversity030104 developmental biologyInfectious DiseasesTraitParasitology[SDE.BE]Environmental Sciences/Biodiversity and Ecologyhuman activitiesInternational journal for parasitology
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Refining the genetic structure and relationships of European cattle breeds through meta-analysis of worldwide genomic SNP data, focusing on Italian c…

2020

AbstractThe availability of genotyping assays has allowed the detailed evaluation of cattle genetic diversity worldwide. However, these comprehensive studies did not include some local European populations, including autochthonous Italian cattle. In this study, we assembled a large-scale, genome-wide dataset of single nucleotide polymorphisms scored in 3,283 individuals from 205 cattle populations worldwide to assess genome-wide autozygosity and understand better the genetic relationships among these populations. We prioritized European cattle, with a special focus on Italian breeds. Moderate differences in estimates of molecular inbreeding calculated from runs of homozygosity (FROH) were o…

0301 basic medicineBoviniGenotypePopulation geneticslcsh:MedicineGenome-wide association studyBiologyRuns of HomozygosityBiodiversità zootecnicaPolymorphism Single NucleotideBiodiversità zootecnica bovini miglioramento geneticoArticleLinkage DisequilibriumSettore AGR/17 - Zootecnica Generale E Miglioramento Genetico03 medical and health sciences0302 clinical medicineMeta-Analysis as TopicAnimalsInbreedingDomesticationlcsh:ScienceGenotypingPhylogenyAnimal breedingGenetic diversityboviniMultidisciplinarylcsh:RHomozygotebiology.organism_classificationCattle breeds genetic diversity SNPs.Europe030104 developmental biologyItalyEvolutionary biologyGenetic structuremiglioramento geneticolcsh:QCattleInbreeding030217 neurology & neurosurgeryGenome-Wide Association StudyScientific Reports
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Genome-wide assessment of diversity and differentiation between original and modern Brown cattle populations

2020

Identifying genomic regions involved in the differences between breeds can provide information on genes that are under the influence of both artificial and natural selection. The aim of this study was to assess the genetic diversity and differentiation among four different Brown cattle populations (two original vs. two modern populations) and to characterize the distribution of runs of homozygosity (ROH) islands using the Illumina Bovine SNP50 BeadChip genotyping data. After quality control, 34 735 SNPs and 106 animals were retained for the analyses. Larger heterogeneity was highlighted for the original populations. Patterns of genetic differentiation, multidimensional scaling, and the neig…

0301 basic medicineCandidate genecandidate genes FST genetic diversity runs of homozygosityGenotypeBiologyRuns of HomozygosityQuantitative trait locusBreedingGenomePolymorphism Single Nucleotide03 medical and health sciencesGeneticsAnimalsGenotypingGenetic diversityruns of homozygosityNatural selectionF-STHomozygote0402 animal and dairy science04 agricultural and veterinary sciencesGeneral Medicinegenetic diversity040201 dairy & animal science030104 developmental biologyGenetics PopulationPhenotypecandidate genes; F-ST; genetic diversity; runs of homozygosityEvolutionary biologyAnimal Science and ZoologyCattleBrown Swisscandidate genes
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