Search results for "genetically-modified"
showing 4 items of 4 documents
Systematic gene overexpression in Candida albicans identifies a regulator of early adaptation to the mammalian gut.
2018
International audience; Candida albicans is part of the human gastrointestinal (GI) microbiota. To better understand how C. albicans efficiently establishes GI colonisation, we competitively challenged growth of 572 signature-tagged strains (~10% genome coverage), each conditionally overexpressing a single gene, in the murine gut. We identified CRZ2, a transcription factor whose overexpression and deletion respectively increased and decreased early GI colonisation. Using clues from genome-wide expression and gene-set enrichment analyses, we found that the optimal activity of Crz2p occurs under hypoxia at 37°C, as evidenced by both phenotypic and transcriptomic analyses following CRZ2 geneti…
Evolution and functional differentiation of recently diverged phytochelatin synthase genes from Arundo donax L.
2019
Plant phytochelatin synthases undergo evolutionarily rapid functional differentiation after duplication, allowing fast and precise adjustment of metal detoxification capacity by modulation of both transcription and enzymatic activity.
Simulation study of the effects of intensified crop management in genetically manipulated maize on arable weed flora and associated fauna
2014
International audience; Cultivation of GM crops with herbicide tolerance is mostly associated with changes in crop and weed management, like simplified rotations, simplified tillage and change from selective herbicides to the broadband glyphosate. All of these management practices decrease weed densities in crops and change their composition. Although weeds cause yield loss and harvest problems, they are an important part of arable biodiversity and offer food and habitat for different groups of animals. A simulation study was conducted to analyse indirect effects of intensified cropping in GM maize on biodiversity. The dynamic crop: weed model FlorSys was used to simulate weed densities and…
Assessing the effect of changes of agricultural practices accompanying herbicide-tolerant crops on agricultural biodiversity. A simulation study with…
2014
International audience