Search results for "gero"
showing 10 items of 2629 documents
Predictors of Participation and Autonomy in People With Multiple Sclerosis.
2019
Abstract Importance: Because multiple sclerosis (MS) affects many life areas, it is important to know how participation and autonomy are associated with the perceived impact of MS on everyday life. Objective: To investigate how perceived quality of life, disease impact, gender, and disease severity predict participation and autonomy in people with MS. Design: Cross-sectional study in which structural equation modeling was used to evaluate relationships between measured variables. Settings: Outpatient clinics in three areas and one inpatient rehabilitation center in Finland. Participants: Convenience sample of 194 people with MS. Outcomes and Measures: Participants completed the Impact on Pa…
Perceived barriers in the outdoor environment and development of walking difficulties in older people
2012
SIR—Older people with mobility limitations often report more barriers in their outdoor environment than people with intact mobility [1]. However, it is uncertain whether older people perceive their environment as problematic because of their mobility limitations or whether the environmental barriers precede incident mobility limitation, as most studies have been limited to cross-sectional analyses [2–5]. Only a few longitudinal studies have shown that barriers in the outdoor environment, such as poor street conditions, poor lighting and heavy traffic, increase the risk for overall functional loss [6, 7] and decrease physical activity participation [8]. More knowledge is needed about the cha…
L26 The Role Of Occupational Therapy In Huntington's Disease
2014
Background We discuss the role of the occupational therapist working with individuals and families affected by Huntington’s disease. Objectives A research by purposes was carried out through the design and implementation of an intervention program aimed at preventing and alleviating the deterioration caused by the disease through training in daily living activities and cognitive stimulation, and coaching the families through monthly monitoring and annual meetings. Method A literature review using structured databases was conducted to identify studies focusing on Occupational Therapy in Huntington’s disease. An intervention program based on the different types, symptoms and stages of the dis…
Interventions aimed to increase independence and well-being in patients with Alzheimer’s disease: Review of some interventions in the Italian context
2018
Abstract Background Alzheimer's disease (AD) represents a huge social and economic burden for the society and caring for individuals with AD is a complex and challenging task that requires a multidisciplinary approach. Studies have shown that several interventions provide beneficial results, but some non-pharmacological interventions have not yet been studied in depth and clinical trials using them are still pending. This review provides a summary of interventions based on paradigms aimed to increase independence and well-being in people with AD, as well as those interventions that decrease caregiver burden in long-term facilties for AD patients in Italy. Methods Narrative review regarding …
Life-Space Mobility in Parkinson's Disease: Associations with Motor and Non-Motor Symptoms.
2019
Background To describe life-space mobility and explore associations of motor and non-motor symptoms with life-space mobility in people with Parkinson’s disease (PD). Methods About 164 community-dwelling persons with PD (mean age 71.6 years, 64.6% men) received a postal survey and a subsequent home visit. Motor assessments included perceived walking difficulties (Walk-12G), mobility (Timed Up and Go test), motor symptoms (UPDRS-III), and freezing of gait (item 3, FOG-Qsa). Non-motor symptoms included depressive symptoms (GDS-15), pain, fatigue (NHP-EN), and global cognition (MoCA). Life-space mobility was assessed with the life-space assessment (LSA). Calculations included composite score (r…
Attributes and definitions of locomotor capacity in older people: a World Health Organisation (WHO) locomotor capacity working group meeting report
2022
not available
Erratum to: Development and validation of the FRAGIRE tool for assessment an older person’s risk for frailty
2016
Background Frailty is highly prevalent in elderly people. While significant progress has been made to understand its pathogenesis process, few validated questionnaire exist to assess the multidimensional concept of frailty and to detect people frail or at risk to become frail. The objectives of this study were to construct and validate a new frailty-screening instrument named Frailty Groupe Iso-Ressource Evaluation (FRAGIRE) that accurately predicts the risk for frailty in older adults. Methods A prospective multicenter recruitment of the elderly patients was undertaken in France. The subjects were classified into financially-helped group (FH, with financial assistance) and non-financially …
Age differences in olfactory affective responses: evidence for a positivity effect and an emotional dedifferentiation
2021
International audience; Studies on aging and hedonic judgment of odors have never been addressed within the empirical frameworks of age-related changes in emotion which state that advancing age is associated with a reduced negativity bias and a less pronounced differentiation between hedonic valence and emotional intensity judgments. Our aim was to examine and extend these age-related effects into the field of odors. Thirty-eight younger adults and 40 older adults were asked to evaluate the hedonic valence, emotional intensity, and familiarity of 50 odors controlled for their pleasantness. Compared to younger adults, older adults rated unpleasant odorants as less unpleasant and showed an in…
Moderate hypofractionated helical tomotherapy for prostate cancer in a cohort of older patients: a mono-institutional report of toxicity and clinical…
2019
Purpose or objective: To evaluate toxicity and outcomes of moderately hypofractionated helical tomotherapy for the curative treatment of a cohort of patients aged ≥ 75 years with localized prostate cancer (PC). Materials and methods: From January 2013 to February 2017, 95 patients with median age 77 years (range 75–88) were treated for PC. 39% were low risk, 33% intermediate risk (IR), 28% high risk (HR). Median iPSA was 9.42 ng/ml (1.6–107). Androgen deprivation was prescribed according to NCCN recommendations. All patients received 70 Gy in 28 fractions to the prostate; 61.6 Gy were delivered to the seminal vesicles for IR; whole pelvis irradiation with a total dose of 50.4 Gy was added i…
The prevalent KRAS exon 2 c.35 G > A mutation in metastatic colorectal cancer patients: a biomarker of worse prognosis and potential benefit of bevac…
2015
Bevacizumab-containing chemotherapy differently predict increased efficacy in KRAS exon 2 mutant and wild-type metastatic colorectal cancer (MCRC) patients. Mutant compared to wild-type status did not significantly affect progression-free survival (PFS) and overall survival (OS) in patients fit for first line bevacizumab-containing FIr-B/FOx regimen, and after progression. In patients unfit for intensive regimens, mutant status significantly affected PFS, while not OS. Codon 12 KRAS mutations differentially affect GTPase function, and confer worse clinical behaviour. Prognostic relevance of the prevalent c.35 G. >. A KRAS mutation was retrospectively evaluated. Fit c.35 G. >. A mutant patie…