Search results for "gero"
showing 10 items of 2629 documents
Impact of COVID-19 on Sustainable University Sports: Analysis of Physical Activity and Positive and Negative Affects in Athletes
2021
The suspension of university activities due to the pandemic affected training and sports competitions. However, some universities adapted online education, allowing students to carry out their activities without being infected by the virus. The aim of this study was to find out the impact of the pandemic on physical activity levels and the positive and negative effects on Chilean university athletes. The information was obtained by applying the PANAS scale and demographic and physical activity variables were also measured. The sample of Chilean university athletes (n = 254) were aged between 18 and 31 years (M = 22.17
Stereoselective synthesis and determination of the cytotoxic properties of spicigerolide and three of its stereoisomers.
2003
Stereoselective syntheses of the naturally occurring, cytotoxic lactone spicigerolide and three nonnatural stereoisomers thereof are described. The commercially available sugar l-rhamnose was in all cases the chiral starting material. Key steps in each of these syntheses were asymmetric Brown allylations and ring-closing metatheses. The cytotoxic activities of the four lactones against a range of tumoral lines were then determined.
Effects of Hypericum Extract on the Expression of Serotonin Receptors
1994
The influence of hypericum extract LI 160 on the expression of serotonin receptors was investigated using a neuroblastoma cell line to establish a model for the regulation of neurotransmitters by immunologically active compounds such as cytokines. The cells were incubated with hypericum extract LI 160 in kinetic form for 2, 4, 6, 8, and 10 hours, then washed. The serotonin receptor expression analysis was compared to that of a placebo control solution. The neuroblastoma cells showed a clearly reduced expression of the serotonin receptors under treatment with hypericum extract. First stimulation experiments with interleukin-1 (IL-1) and hypericum extract suggest that a further reduction of …
Early bearing and vegetative growth of 153 Sicilian olive accessions
2018
In 2014, an olive germplasm collection was established in south-western Sicily, Italy. The collection included 153 Sicilian accessions and 3 international varieties (reference), each with 7 trees, spaced at 5×2 m and trained to hedgerow system. The aim of the trial was to study early growth and yield responses of the accessions to super-high planting density (SHD). Trunk cross sectional area, tree height, pruning weights, shoot positioning, blooming and fruit yield (kg tree-1) were measured in 2015 and 2016. Based on trunk growth and amount of prunings, the 153 accessions were separated into four categories of vigor as it follows: very high vigor (6 accessions), high vigor (13), medium vigo…
Health system reforms and the needs of the ageing population : an analysis of recent policy paths and reform trends in Finland and Sweden
2022
AbstractPopulation ageing with an increasing number of people experiencing complex health and social care needs challenges health systems. We explore whether andhow health system reforms and policy measures adopted during the past two decades in Finland and Sweden reflect and address the needs of the older people. We discuss health system characteristics that are important to meet the care needs of older people and analyse how health policy agendas have highlighted these aspects in Finland and Sweden. The analysis is based on “most similar cases”. The two countries have rather similar health systems and are facing similar challenges. However, the policy paths to address these challenges are…
Knowledge-based modelling applied to synucleinopathies
2015
International audience; The adoption of telemedicine technologies has enabled collaborative programs involving a variety of links among distributed medical structures and health officials and professionals. The use for telemedicine for transmission of medical data and the possibility for several distant physicians to share their knowledge on given medical cases provides clear benefits, but also raises several unsolved conceptual and technical challenges. The seamless exchange and access of medical information between medical structures, health professionals, and patients is a prerequisite for the harmonious development of this new medical practice. This paper proposes a new approach of sema…
Differential evolution of PSA-NCAM expression during aging of the rat telencephalon
2007
Changes in the ability of neuronal networks to undergo structural remodeling may be involved in the age-associated cognitive decline. The polysialylated form of the neural cell adhesion molecule (PSA-NCAM) declines dramatically during postnatal development, but persists in several regions of the young-adult rat telencephalon, where it participates, through its anti-adhesive properties, in neuronal structural plasticity. However, PSA-NCAM expression during aging has only been studied in the dentate gyrus and the piriform cortex layer II, where it is strongly downregulated in adult (middle-aged) individuals. Using immunohistochemistry, we have observed that in most of the telencephalic areas …
Narrativa dei Caraibi nel nuovo millennio
2020
L’etichetta “Letterature franco-caraibica” utilizzata, per convenzione, dalla critica per indicare unitariamente la produzione letteraria in lingua francese della regione centrale del Continente americano è assai impropria. La regione dei Caraibi abbraccia, infatti, sia alcune delle isole dell’arcipelago delle Piccole Antille (Martinica, Guadalupa), sia l’isola di Haïti, che fa parte delle Grandi Antille, che la Guiana incastonata sulla costa orientale dell’America meridionale. Pur nella diversità dei movimenti ideologici e degli avvenimenti storici che si sono succeduti nella regione, le opere letterarie degli scrittori caraibici francofoni, nel loro insieme, hanno oscillato, e continuano …
Caraibi: un "archipel inachevé"
2018
L’etichetta “Letterature franco-caraibica” utilizzata, per convenzione, dalla critica per indicare unitariamente la produzione letteraria in lingua francese della regione centrale del Continente americano è assai impropria. La regione dei Caraibi abbraccia, infatti, sia alcune delle isole dell’arcipelago delle Piccole Antille (Martinica, Guadalupa), sia l’isola di Haïti, che fa parte delle Grandi Antille, che la Guiana incastonata sulla costa orientale dell’America meridionale. Pur nella diversità dei movimenti ideologici e degli avvenimenti storici che si sono succeduti nella regione, le opere letterarie degli scrittori caraibici francofoni, nel loro insieme, hanno oscillato, e continuano …
Detectability of cannabinoids in the serum samples of cannabis users: Indicators of recent cannabis use? A follow‐up study
2021
Forensic toxicologists are frequently required to predict the time of last cannabis consumption. Several studies suggested the utility of minor cannabinoids as indicators of recent cannabis use. Because several factors influence blood cannabinoid concentrations, the interpretation of serum cannabinoid concentrations remains challenging. To assess the informative value of serum cannabinoid levels in cannabis users (in total N = 117 patients, including 56 patients who stated an exact time of last cannabis use within 24 h before blood sampling), the detectability of cannabinoids, namely delta-9-tetrahydrocannabinol (delta-9-THC), 11-hydroxy-delta-9-THC, 11-nor-9-carboxy-delta-9-THC, cannabichr…