Search results for "gestational age"

showing 10 items of 266 documents

Risk factors for bronchiolitis hospitalization during the first year of life in a multicenter Italian birth cohort

2015

Background: Respiratory Syncytial Virus (RSV) is one of the main causes of respiratory infections during the first year of life. Very premature infants may contract more severe diseases and 'late preterm infants' may also be more susceptible to the infection. The aim of this study is to evaluate the risk factors for hospitalization during the first year of life in children born at different gestational ages in Italy. Methods: A cohort of 33-34 weeks gestational age (wGA) newborns matched by sex and age with two cohort of newborns born at 35-37 wGA and >37 wGA were enrolled in this study for a three-year period (2009-2012). Hospitalization for bronchiolitis (ICD-9 code 466.1) during the f…

PalivizumabMalePediatricsmedicine.medical_specialtyMultivariate analysisGestational AgeRespiratory Syncytial Virus InfectionsRespiratory syncytial virusPediatricsCohort Studies03 medical and health sciences0302 clinical medicineSex FactorsRisk Factors030225 pediatricsmedicineBronchiolitis ViralHumans030212 general & internal medicineBronchiolitis; Children; Hospitalization; Palivizumab; Prophylaxis; Respiratory syncytial virus; Risk factor; Breast Feeding; Bronchiolitis Viral; Cohort Studies; Crowding; Female; Gestational Age; Hospitalization; Humans; Infant; Infant Newborn; Italy; Male; Multivariate Analysis; Respiratory Syncytial Virus Infections; Risk Factors; Sex Factors; Pediatrics Perinatology and Child HealthViralRisk factorChildrenPalivizumabBronchiolitis Hospitalization Risk factor Respiratory syncytial virus Prophylaxis Palivizumab Childrenbusiness.industryProphylaxisResearchInfant NewbornGestational ageInfantPerinatology and Child Healthmedicine.diseaseNewborn3. Good healthHospitalizationBreast FeedingCrowdingItalyBronchiolitisMultivariate AnalysisGestationBronchiolitisFemaleRisk factorbusinessBreast feedingmedicine.drugCohort study
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Bronchiolitis: The New American Academy of Pediatrics Guidelines

2008

Respiratory Syncytial Virus (RSV) is the leading cause of hospitalization for lower respiratory tract infections (LRTI) in young children worldwide. RSV is an important cause of LRTI in infants and a variety of factors, such as gender, age at admission, gestational age, birth weight, and exposure to tobacco smoke and breast feeding may affect the prevalence of RSV-related disease and, possibly, the risk of developing asthma-like symptoms during the school years. AAP in 2006 formulated the new guidelines on diagnosis and management of bronchiolitis, giving recommendations on different conditions requesting clinical decisions also in terms of prevention.

PalivizumabPediatricsmedicine.medical_specialtyBirth weightRespiratory Syncytial Virus InfectionsDiseaseAntibodies Monoclonal HumanizedAntiviral AgentsTobacco smokeRisk FactorsPrevalencemedicineBronchiolitis ViralHumansPharmacology (medical)PalivizumabPharmacologyEvidence-Based MedicineRespiratory tract infectionsbusiness.industryAntibodies MonoclonalGestational agemedicine.diseaserespiratory tract diseasesInfectious DiseasesOncologyBronchiolitisPractice Guidelines as TopicBronchiolitisbusinessBreast feedingmedicine.drugJournal of Chemotherapy
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Early development of human Merkel cells.

1992

Human fetal Merkel cells are now generally considered to be epidermal derivatives. Previous studies using antibodies against the simple epithelial cytokeratins (CKs), 8 and 18, have demonstrated the presence of these cells in the epidermis at as early as fetal week 10 to 12. Using antibodies against CK 20 whose expression within the skin is restricted to Merkel cells, we applied immunofluorescence and immunoperoxidase microscopy to analyze earlier embryonic and fetal human skin (wk 7 to 9). We were able to demonstrate the first Merkel cells at as early as fetal wk 8, i.e., at the same time as the epidermis starts to develop an intermediate, third layer, characterized by the expression of CK…

Pathologymedicine.medical_specialtyFluorescent Antibody TechniqueHuman skinGestational AgeDermatologyKeratin-20BiologyImmunofluorescenceBiochemistryImmunoenzyme TechniquesBasal (phylogenetics)FetusIntermediate Filament ProteinsEndocrine GlandsmedicineHumansMolecular BiologyFetusintegumentary systemImmunoperoxidasemedicine.diagnostic_testAntibodies MonoclonalEmbryonic stem cellmedicine.anatomical_structureEpidermal CellsEpidermisEpidermisMerkel cellHairExperimental dermatology
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Bioeffects of ultrasound: an experimental study on human embryos.

1991

Abstract The foetuses of 10 women at 9–12 weeks gestation were irradiated with ultrasound under typical diagnostic exposure conditions immediately prior to abortion. Electron microscopy of liver fragments revealed neither morphological nor structural changes.

Pathologymedicine.medical_specialtyTime FactorsAcoustics and Ultrasonicsbusiness.industryUltrasoundEmbryoGestational AgeAbortionUltrasonography PrenatalLiverPregnancyembryonic structuresMedicineGestationHumansFemalebusinessreproductive and urinary physiologyUltrasonics
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Merkel cells in ontogenesis of human nails

1993

Digital skin of human fetuses is known to contain a particularly high concentration of Merkel cells. Using antibodies against the simple epithelial cytokeratins (CK) 18 and 20, which are sensitive and specific Merkel cell markers, we studied immunohistochemically the main adnexal structure of digital skin, the nail anlage, in human fetuses (9-22 weeks of gestation) for the presence of Merkel cells. As early as week 9 some clustered Merkel cells were detected in the early matrix primordium. In specimens of week 12-15, abundant Merkel cells were found in the nail anlagen, particularly in the epithelium of the proximal nail-fold and the dorsal and ventral side of the apex region. In contrast, …

Pathologymedicine.medical_specialtyanimal structuresGestational AgeKeratin-20DermatologyMatrix (biology)BiologyIntermediate Filament ProteinsDermisKeratinmedicineHumansskin and connective tissue diseaseschemistry.chemical_classificationintegumentary systemKeratin 20General MedicineAnatomyImmunohistochemistryNeurosecretory SystemsEpitheliummedicine.anatomical_structureNailschemistryNail (anatomy)KeratinsMerkel cellNail matrixArchives of Dermatological Research
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Formation of Epidermal and Dermal Merkel Cells During Human Fetal Skin Development

1986

The origin of Merkel cells is still a matter of debate, specifically the question of whether they are derived from epithelial cells of the epidermis or from immigrated neural crest cells. As an argument for the latter hypothesis the occurrence of dermal, nerve-associated Merkel cells in human fetal skin has often been mentioned. Therefore, we analyzed the distribution of Merkel cells in epidermis and dermis of plantar skin of human embryos and fetuses, ranging in gestational age between 7 and 17 weeks. Merkel cells were identified by immunocytochemistry on frozen sections using antibodies against simple epithelium-type cytokeratins and by electron microscopy. In the 17-week-old fetus, 17% o…

Pathologymedicine.medical_specialtyanimal structuresImmunocytochemistryGestational AgeDermatologyBiologyBiochemistryCytokeratinEmbryonic and Fetal DevelopmentDermismedicineHumansMolecular BiologySkinFetusintegumentary systemNeural crestCell BiologyEpitheliumMicroscopy Electronmedicine.anatomical_structureEpidermal CellsEpidermisEpidermisMerkel cellJournal of Investigative Dermatology
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Exposure to trihalomethanes through different water uses and birth weight, small for gestational age, and preterm delivery in Spain

2011

Background: Evidence associating exposure to water disinfection by-products with reduced birth weight and altered duration of gestation remains inconclusive. Objective: We assessed exposure to trihalomethanes (THMs) during pregnancy through different water uses and evaluated the association with birth weight, small for gestational age (SGA), low birth weight (LBW), and preterm delivery. Methods: Mother–child cohorts set up in five Spanish areas during the years 2000–2008 contributed data on water ingestion, showering, bathing, and swimming in pools. We ascertained residential THM levels during pregnancy periods through ad hoc sampling campaigns (828 measurements) and regulatory data (264 me…

PediatricsFetus -- CreixementBathingHealth Toxicology and MutagenesisEspaña:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Cohort Studies:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models Theoretical [Medical Subject Headings]small for gestational agePregnancynewbornFemeninosExposición a Riesgos Ambientales:Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproductive Physiological Processes::Reproduction::Pregnancy [Medical Subject Headings]:Geographicals::Geographic Locations::Europe::Spain [Medical Subject Headings]water pollutionInfeccions respiratòries -- EpidemiologiaAdultodisinfection by-products:Named Groups::Persons::Age Groups::Infant::Infant Newborn::Infant Low Birth Weight [Medical Subject Headings]Modelos TeóricosEnvironmental exposurepremature birthNacimiento PrematuroHumanos:Health Care::Environment and Public Health::Public Health::Environmental Pollution::Environmental Exposure [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models Statistical::Logistic Models [Medical Subject Headings]Premature birthInfant Small for Gestational AgeGestation:Named Groups::Persons::Age Groups::Infant::Infant Newborn::Infant Low Birth Weight::Infant Small for Gestational Age [Medical Subject Headings]Femaleepidemiologymedicine.symptomAigua -- DepuracióAdultmedicine.medical_specialtytrihalomethanesContaminantes Químicos del AguaEmbarazoBirth weight:Named Groups::Persons::Age Groups::Infant::Infant Newborn [Medical Subject Headings]Embaràs -- Aspectes nutricionalsRecién nacidoRecién Nacido Pequeño para la Edad GestacionalEnvironmental healthmedicine:Named Groups::Persons::Age Groups::Adult [Medical Subject Headings]cohort studyModelos LogísticosHumanslow birth weightEpidemiologiaRecién Nacido de Bajo Peso:Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Hydrocarbons Halogenated::Trihalomethanes [Medical Subject Headings]Pregnancybusiness.industryTrihalometanoResearchPublic Health Environmental and Occupational HealthInfant Newbornbirth weightEnvironmental ExposureInfant Low Birth WeightModels Theoreticalmedicine.diseaseLow birth weightLogistic Models:Check Tags::Female [Medical Subject Headings]Spain:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies [Medical Subject Headings]Small for gestational age:Chemicals and Drugs::Chemical Actions and Uses::Toxic Actions::Environmental Pollutants::Water Pollutants::Water Pollutants Chemical [Medical Subject Headings]:Diseases::Female Urogenital Diseases and Pregnancy Complications::Pregnancy Complications::Obstetric Labor Complications::Obstetric Labor Premature::Premature Birth [Medical Subject Headings]businessEstudios de CohortesWater Pollutants Chemical
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Correlation between neonatal outcomes of twins depends on the outcome : Secondary analysis of twelve randomised controlled trials

2018

ObjectiveTo estimate the magnitude of the correlation between neonatal outcomes of twins and demonstrate how this information can be used in the design of randomised controlled trials (RCTs) in women with twin pregnancies.DesignSecondary analysis of data from 12 RCTs.SettingObstetric care in multiple countries, 2004-2012.Population or sample4504 twin pairs born to women who participated in RCTs to assess treatments given during pregnancy.MethodsIntraclass correlation coefficients (ICCs) were estimated using log-binomial and linear models.Main outcome measuresPerinatal death, respiratory distress syndrome, bronchopulmonary dysplasia, intraventricular haemorrhage, necrotising enterocolitis, s…

PediatricsNeonatal intensive care unitIntraclass correlationPerinatal DeathBayesian analysisintraclass correlation coefficientInfant Newborn DiseasesCorrelationpowerDOUBLE-BLIND0302 clinical medicinePregnancyMedicine030212 general & internal medicineCorrelation of DataRandomized Controlled Trials as Topiceducation.field_of_study030219 obstetrics & reproductive medicineRespiratory distressPregnancy OutcomeObstetrics and Gynecologytwinssample sizeINTRACLUSTER CORRELATIONFemaleAdultmedicine.medical_specialtyPRETERM BIRTHPopulationGestational AgeArticle03 medical and health sciencesSMALL CLUSTERSPREGNANCIESHumanseducationPregnancyModels Statisticalbusiness.industryInfant NewbornPROGESTERONEmedicine.diseasePREVENTIONmeta-analysisBronchopulmonary dysplasiaSample size determinationPregnancy TwinMULTIPLE BIRTHSbusinessCORRELATION-COEFFICIENT17-ALPHA-HYDROXYPROGESTERONE CAPROATE
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Burkitt’s lymphoma in pregnant woman: Difficult management of a rare case

2020

Highlights • Burkitt’s lymphoma, an aggressive non-Hodgkin lymphoma, is extremely rare during pregnancy. • Lymphoma of the small intestine is often overlooked in the early stages of the disease. • We described a multidisciplinary approach, cesarean section with surgical intestinal exploration.

Pediatricsmedicine.medical_specialtyBurkitt’s lymphomaIntestinal involvementNauseaCase ReportDisease03 medical and health sciences0302 clinical medicineimmune system diseasesPregnancyhemic and lymphatic diseasesmedicineNon-Hodgkin lymphomaPregnancyBurkitt's lymphomabusiness.industryGestational agemedicine.diseaseLymphoma030220 oncology & carcinogenesisVomitingGestation030211 gastroenterology & hepatologySurgerymedicine.symptombusinessBurkitt's lymphomaInternational Journal of Surgery Case Reports
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Maternal Vitamin D Status in Pregnancy and Risk of Lower Respiratory Tract Infections, Wheezing, and Asthma in Offspring

2011

Background Adequate vitamin D status in mothers during pregnancy may influence the health status of the child later in life. We assessed whether maternal circulating 25-hydroxyvitamin D (25[OH]D) concentrations in pregnancy are associated with risk of lower respiratory tract infections, wheezing, and asthma in the offspring. Methods Data were obtained from 1724 children of the INfancia y Medio Ambiente (INMA) Project, a population-based birth cohort study. Maternal circulating 25(OH)D concentrations were measured in pregnancy (mean gestational age = 12.6 [SD = 2.5] weeks). When the child was age 1 year, parents were asked if their child had a physician-confirmed history of lower respiratory…

Pediatricsmedicine.medical_specialtyEpidemiologyOffspringPopulationLower riskCohort StudiesPregnancyHumansMedicineVitamin DChildeducationRespiratory Tract InfectionsRespiratory SoundsAsthmaPregnancyeducation.field_of_studyRespiratory tract infectionsbusiness.industryGestational ageOdds ratioVitamin D Deficiencymedicine.diseaseAsthmaPregnancy ComplicationsSpainChild PreschoolFemalebusinessEpidemiology
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