Search results for "goals"
showing 10 items of 643 documents
Ethnographic Knowledge in Urban Planning:Bridging the Gap between the Theories of Knowledge-Based and Communicative Planning
2021
Publisher Copyright: © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. ‘Knowledge-based’ approaches have recently made a breakthrough in urban planning. How to develop balance in knowledge-based planning between abstract and scientific knowledge, on the one hand, and ‘local knowledge’ on the other hand has been long debated. To this debate, we add a form of knowledge with potential for sustainable urban planning, i.e. ethnographic knowledge that could transmit an understanding of urban dwellers’ daily practices and values to planning organisations. Theoretical literature is the foundation of our argument, which we illustrate with a case study involvin…
Molecular mechanism of T-cell protein tyrosine phosphatase (TCPTP) activation by mitoxantrone.
2013
T-cell protein tyrosine phosphatase (TCPTP) is a ubiquitously expressed non-receptor protein tyrosine phosphatase. It is involved in the negative regulation of many cellular signaling pathways. Thus, activation of TCPTP could have important therapeutic applications in diseases such as cancer and inflammation. We have previously shown that the α-cytoplasmic tail of integrin α1β1 directly binds and activates TCPTP. In addition, we have identified in a large-scale high-throughput screen six small molecules that activate TCPTP. These small molecule activators include mitoxantrone and spermidine. In this study, we have investigated the molecular mechanism behind agonist-induced TCPTP activation.…
The Psychological Science Accelerator’s COVID-19 rapid-response dataset
2023
Funder: Amazon Web Services (AWS) Imagine Grant
A computationally fast alternative to cross-validation in penalized Gaussian graphical models
2015
We study the problem of selection of regularization parameter in penalized Gaussian graphical models. When the goal is to obtain the model with good predicting power, cross validation is the gold standard. We present a new estimator of Kullback-Leibler loss in Gaussian Graphical model which provides a computationally fast alternative to cross-validation. The estimator is obtained by approximating leave-one-out-cross validation. Our approach is demonstrated on simulated data sets for various types of graphs. The proposed formula exhibits superior performance, especially in the typical small sample size scenario, compared to other available alternatives to cross validation, such as Akaike's i…
A spatial analysis of Italian unemployment differences
2008
Using spatial econometric models, this paper focuses attention on the spatial structure of provincial unemployment disparities of Italian provinces for the year 2003. On the basis of findings from the economic literature and of the available socio-economic data, various model specifications including supply- and demand-side variables are tested. Further we use ESDA analysis as equivalent to integration analysis on time series; therefore it is applied on each variable, dependent and independent, involved in the statistical model. The suggestions of ESDA lead us to the most adequate statistical model, which estimates indicate that there is a significant degree of neighbouring effect (i.e. pos…
Mobile Mental Wellness Training for Stress Management: Feasibility and Design Implications Based on a One-Month Field Study
2013
Background: Prevention and management of work-related stress and related mental problems is a great challenge. Mobile applications are a promising way to integrate prevention strategies into the everyday lives of citizens. Objective: The objectives of this study was to study the usage, acceptance, and usefulness of a mobile mental wellness training application among working-age individuals, and to derive preliminary design implications for mobile apps for stress management. Methods: Oiva, a mobile app based on acceptance and commitment therapy (ACT), was designed to support active learning of skills related to mental wellness through brief ACT-based exercises in the daily life. A one-month …
Reviewing the impact of problem structure on planning: a software tool for analyzing tower tasks.
2010
Cognitive, clinical, and neuroimaging studies on planning abilities most frequently implement the Tower of London task or one of its variants. Yet, cumulating evidence from a series of experiments suggests that the commonly used approximation of problem difficulty in terms of the minimum number of moves for goal attainment is too coarse a measure for the underlying cognitive operations, and in some cases may be even misleading. Rather, problem difficulty can be more specifically characterized by a set of structural task parameters such as the number and nature of optimal and suboptimal solution paths, the required search depths, the patterns of intermediate and goal moves, goal hierarchies …
The Education Production Function reviewed in the framework of Education For All in Sub-Saharan Africa: from theoretical and methodological bounds to…
2007
The Coleman report (1966) was the first of numerous researches exploring quality of learning determinants analysis. With the Education Production Function (EPF), economists have greatly contributed to the extension of this research domain. Actually, empirical works are leading the field with important methodological debates which have fuelled controversies (Hanushek, 2003; Krueger, 2003). Thus, methodological issues have particularly rallied researchers' interests on empirical estimations, while academic researches on the renewal of the theoretical framework have remained scarce despite obvious bounds. Without contesting the validity of miscellaneous estimation problems and the necessity of…
Dzīves mērķu, pašefektivitātes saistība ar subjektīvās labklājības rādītājiem sievietēm
2020
Bakalaura darba pētījuma mērķis ir izprast dzīves mērķu pašefektivitātes saistību ar subjektīvās labklājības rādītājiem sievietēm. Pētot konstruktu teorētisko bāzi tika izvirzīts, ka iekšējā satura dzīves mērķiem ir saistība ar subjektīvo labklājību, un balstoties uz personīgo vērtību izvirzītajiem dzīves mērķiem un indivīda pašefektivitātes līmeni, izvirzīto mērķu sasniegšana ietekmē subjektīvās labklājības līmeni. Pētījuma respondentu izlasi veido 60 sievietes vecuma grupā no 20-50 gadiem , kuru vidējais vecums ir 33,83 gadi. Dzīves mērķu, pašefektivitātes un subjektīvās labklājības noteikšanai tika pielietotas Dzīves mērķu skala (Aspirations Index; Kasser & Ryan, 1996), Latvijā aptauju a…
The challenge for school-based teacher educators : establishing teaching and supervision goals
2019
School-based teacher educators (SBTEs) should be able to set goals in two roles – as a teacher and as a supervisor of student teachers. The purpose of the study was to investigate school-based teacher educators’ teaching and supervising goals and to identify how teachers in the role of supervisors perceived university expectations. Thematic analysis indicated that teachers have difficulty establishing goals for themselves as teachers and supervisors. Their teaching goals proceeded from curricula and focused on their pupils’ cognitive development, whilst their perceptions about supporting pupils’ social development were vague. Teachers were unaware of what exactly universities expected of th…