Search results for "goals"

showing 10 items of 643 documents

Connection between Absorption Properties and Conformational Changes in Deinococcus radiodurans Phytochrome

2014

Phytochromes consist of several protein domains and a linear tetrapyrrole molecule, which interact as a red-light-sensing system. In this study, size-exclusion chromatography and light-scattering techniques are combined with UV-vis spectroscopy to investigate light-induced changes in dimeric Deinococcus radiodurans bacterial phytochrome (DrBphP) and its subdomains. The photosensory unit (DrCBD-PHY) shows an unusually stable Pfr state with minimal dark reversion, whereas the histidine kinase (HK) domain facilitates dark reversion to the resting state. Size-exclusion chromatography reveals that all phytochrome fragments remain as dimers in the illuminated state and dark state. Still, the elut…

biologyPhytochromeProtein ConformationElutionProtein domainHistidine kinaseta1182Deinococcus radioduransSDG 10 - Reduced Inequalitiesbiology.organism_classificationBiochemistryTetrapyrroleProtein Structure Tertiarychemistry.chemical_compoundDark stateBacterial ProteinsBiochemistrychemistry/dk/atira/pure/sustainabledevelopmentgoals/reduced_inequalitiesBiophysicsMoleculeSpectrophotometry UltravioletDeinococcusPhytochromeBiochemistry
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Significance of immunohistochemistry biomarkers in prediction of malignant transformation of oral lichen planus

2022

Background: Oral lichen planus (OLP) is a chronic inflammatory disorder with increased risk for malignant transformation. Biomarker validation is a pivotal step in moving newly discovered biomarkers towards clinical implementation. We performed a systematic review of studies on biomarkers related to OLP, wherein biomarkers have been described in at least two independent studies. Our aim was to determine whether any of these biomark-ers might be promising in predicting the increased risk of malignant transformation of OLP. Material and Methods: We searched the following databases until August 2021: PUBMED, EMBASE, and Web of Science. Due to high heterogeneity, a qualitative rather than quant…

bisphosphonate osteonecrosisp53malignant transformationP21bone densitybiomarkerscomputed tomographycervical vertebraeImmunohistochemistryCell Transformation NeoplasticjawOtorhinolaryngologySDG 3 - Good Health and Well-beingProliferating Cell Nuclear AntigenOral lichen planusBCl-2Humans/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingPCNAMouth NeoplasmsSurgeryGeneral DentistryUNESCO:CIENCIAS MÉDICASLichen Planus OralMedicina oral patologia oral y cirugia bucal
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Business model innovation for the SDGs: Towards a performance measurement system

2019

Business model innovation can be a key element for realizing the transformation needed to accomplish the Sustainable Development Goals. However, literature on Sustainable Business Models still lacks quantitative-oriented approaches and tools supporting the implementation and assessment of business model innovations for sustainability. This study proposes an eight-phase performance measurement system supporting organisations in implementing, assessing and managing business model innovations aiming at contributing to the Sustainable Development Goals. The performance measurement system builds upon literature on business model innovation for sustainability, performance measurement and manageme…

business model innovation Sustainable Development Goals (SDGs) sustainability Performance Measurement System (PMS)Settore SECS-P/07 - Economia Aziendale
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Repeatability Study on a Classifier for Gastric Cancer Detection from Breath Sensor Data

2019

The SNIFFPHONE device is a portable multichannel gas sensor, aiming to detect gastric cancer (GC) from breath samples. It employs gold nanoparticle (GNP) sensors reacting to volatile organic compounds (VOCs) in the exhaled breath, a non-invasive technique to support early diagnosis. This study evaluates the repeatability of the SNIFFPHONE classification result for measurements conducted on healthy subjects over a short period of time of less than 10 minutes. Due to the portable nature of the device, repeatability is studied with respect to varying measurement location. We find the classification results repeatable with a statistically significant 81 % Pearson correlation coefficient, even t…

business.industryBreath sensorHealthy subjects02 engineering and technologyCancer detectionRepeatability021001 nanoscience & nanotechnologyCancer detectionPearson product-moment correlation coefficient03 medical and health sciencessymbols.namesake0302 clinical medicineSDG 3 - Good Health and Well-beingVolatile organic compunds030220 oncology & carcinogenesisClassification resultsymbolsMedicine/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingDecision support for health0210 nano-technologybusinessGastric cancerClassifier (UML)Biomedical engineering
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Compliance and non-compliance with a superordinate directive document

2012

Published version of an article in the journal: Public Organization Review. Also available from the publisher at: http://dx.doi.org/10.1007/s11115-012-0206-7 We report a study of how a Norwegian regional health care agency directive document was complied with at the subordinate hospital level. We found tight coupling for the activity and budget requirements and loose coupling and decoupling for the other requirements in the document. Furthermore, rather than pursuing their own self- and group interests the hospital actors held an overall effectiveness logic.

business.industryHospital levelNorwegianPublic relationsLoose couplingDirectiveSuperordinate goalscompliancelanguage.human_languagedecouplingdirectivesNon complianceHealth carelanguageBusiness Management and Accounting (miscellaneous)VDP::Social science: 200::Political science and organizational theory: 240BusinesshospitalsLawPublic finance
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Sepsis in head and neck cancer patients treated with chemotherapy and radiation: literature review and consensus

2015

Abstract: The reporting of infection/sepsis in chemo/radiation-treated head and neck cancer patients is sparse and the problem is underestimated. A multidisciplinary group of head and neck cancer specialists from Italy met with the aim of reaching a consensus on a clinical definition and management of infections and sepsis. The Delphi appropriateness method was used for this consensus. External expert reviewers then evaluated the conclusions carefully according to their area of expertise. The paper contains seven clusters of statements about the clinical definition and management of infections and sepsis in head and neck cancer patients, which had a consensus. Furthermore, it offers a revie…

cancer patientpathogenesipositron emission tomographyhealthcare associated infectionSettore MED/06 - Oncologia Medicapatient monitoringradiodiagnosimedicine.medical_treatmentChemotherapy; Head and neck cancer; Radiotherapy; SepsisthrombocytopeniaReviewblood cultureorgan injurymedical terminologyMedicineHead and neck cancermetabolic acidosiC reactive proteinHead and Neck Neoplasmmedical specialisttreatment withdrawalconsensus developmentHematologyclinical practicesystemic inflammatory response syndromeItalyOncologyHead and Neck Neoplasmslaboratory testthrombocytosichemically induced/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingchemotherapy; head and neck cancer; radiotherapy; sepsis; oncology; hematology; geriatrics and gerontologyorgan perfusionhospitalizationHumansepsis Head and Neck Neoplasmmedicine.medical_specialtySettore MED/17 - Malattie InfettiveSepsibacterium culturediagnostic approach routefluorodeoxyglucosecancer chemotherapySepsisSDG 3 - Good Health and Well-beingSepsiscancer radiotherapyfollow upChemotherapyHumansinfection riskIntensive care medicineprocalcitonin antimicrobial therapyChemotherapyRadiotherapybusiness.industrydisease predispositionHead and neck cancerlactic acidChemotherapy; Head and neck cancer; Radiotherapy; Sepsis; Humans; Italy; Head and Neck Neoplasms; Sepsis; Hematology; Oncology; Geriatrics and Gerontologymedicine.diseasemortalityDelphi studyRadiation therapyinflammationincidencehyperglycemiaHuman medicineGeriatrics and Gerontologybusiness
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Development of a European consensus from dentists, dental hygienists and physicians on a standard for oral health care in care-dependent older people…

2020

ObjectivesThis study aimed to obtain a consensus on oral health policy, access to dental care, oral hygiene measures and training levels.BackgroundPoor oral health is widespread in care-dependent older people, but no consensus for a minimum standard of oral health care exists yet.MethodsThe e-Delphi approach was applied to a selected panel of interdisciplinary experts. Data analysis was based on three measurements: (a) ≥70% of experts’ opinion fall into category “agree or strongly agree,” (b) median score on the 5-point Likert scale ≥4, (c) interquartile range ≤1.ResultsA total of 31 experts from 17 European countries participated in this survey. Agreement was achieved for a compulsory dent…

care-dependent older adulte-Delphi studyInstitutionalised older adultsDelphi TechniqueDentistsDelphi methodgeriatric oral careOral Health0302 clinical medicine80 and overMedicine030212 general & internal medicine610 Medicine & healthAged 80 and overinstitutionalised older adults.Care-dependent older adultsE-Delphi studyReference Standardsddc:617.6care-dependent older adults; e-Delphi study; geriatric oral care; institutionalised older adults; Aged; Aged 80 and over; Consensus; Delivery of Health Care; Delphi Technique; Dental Hygienists; Dentists; Europe; Humans; Reference Standards; Oral Health; PhysiciansEurope/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingDental Hygienistsmedicine.medical_specialtyConsensusOral hygieneRemovable prosthodontics03 medical and health sciencesstomatognathic systemSDG 3 - Good Health and Well-beingGeneral DentistryPhysicianscare-dependent older adultsHumansGeneral DentistryAgedbusiness.industryConflict of interest030206 dentistryFocus groupstomatognathic diseasesinstitutionalised older adultsGeriatric oral careFamily medicineddc:618.97Oral health careGeriatrics and GerontologybusinessOlder peopleDelivery of Health CareGerodontologyREFERENCES
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Correlation of wood-based components and dewatering properties of waste activated sludge from pulp and paper industry.

2010

Large amounts of wet sludge are produced annually in municipal and industrial wastewater treatment. Already in pulp and paper industry, more than ten million tons of primary sludge, waste activated sludge, and de-inking sludge is generated. Waste activated sludge contains large quantities of bound water, which is difficult to dewater. Low water content would be a matter of high calorific value in incineration but it also has effects on the volume and the quality of the matter to be handled in sludge disposal. In this research waste activated sludges from different pulp and paper mills were chemically characterised and dewatered. Correlations of chemical composition and dewatering properties…

characterisationPaperEnvironmental EngineeringIndustrial WasteIndustrial wastewater treatment/dk/atira/pure/sustainabledevelopmentgoals/sustainable_cities_and_communitiespulp and paper industrywood-based componentsWater Science and TechnologyWaste managementSewageWaterPulp and paper industryDewateringWoodSDG 11 - Sustainable Cities and CommunitiesMixed liquor suspended solidsIncinerationWaste treatmentsludgeActivated sludgeEnvironmental scienceSewage treatmentSludgedewateringWater science and technology : a journal of the International Association on Water Pollution Research
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Increased sulfate availability in saline water promotes hydrogen sulfide production in fish organic waste

2020

The risk of hydrogen sulfide (H2S) production can be a challenge in marine land-based recirculating aquaculture systems (RAS). Hydrogen sulfide is a toxic gas that can cause massive fish mortality even at low concentrations, and in addition, serious odour problems in the surroundings. It is a bacterial by-product originating from the degradation of organic matter in sulfur-rich waters such as marine waters. In order to hinder H2S production in marine land-based RAS, more information on the H2S production conditions and the associated microbiology is needed. In this study, the production of H2S from rainbow trout (Oncorhynchus mykiss) organic waste was examined using a novel H2S measurement …

chemistry.chemical_classificationChemistryHydrogen sulfideBiodegradable wasteAquatic Scienceequipment and suppliesSaline waterSulfateSulfate reducing bacteria/dk/atira/pure/sustainabledevelopmentgoals/life_below_waterSalinitychemistry.chemical_compoundEnvironmental chemistryOrganic matterSeawaterSeawaterOrganic matterSDG 14 - Life Below WaterSulfate-reducing bacteriaSulfateHydrogen sulfideAquacultural Engineering
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Influence of patient-related factors on intraoperative blood loss during double opposing Z-plasty Furlow palatoplasty and buccal fat pad coverage:A p…

2022

Background: Surgical procedures including palatoplasty have a risk for complications. The aim of this study was to investigate the intraoperative and early postoperative blood loss using the buccal fat pad (BFP) during cleft lip and/or cleft palate (CL/P) surgery. Material and Methods: This prospective study included a total of 109 patients with cleft palate (CP) during a three-month period of treatment at Hasanuddin University Dental Hospital (permanent center) and charity trips in rural parts of Eastern Indonesia. All patients were treated with DOZ Furlow technique combined with BFP graft. Before and after surgery, the total amount of intraoperative blood loss was calculated by measuring …

cleft palateBuccal fat padSDG 3 - Good Health and Well-being/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingcomplicationcleft lippalatoplastyGeneral DentistryUNESCO:CIENCIAS MÉDICAS
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