Search results for "granuloma"
showing 10 items of 170 documents
Inflammatory pituitary lesions
2021
Abstract Inflammatory pituitary lesions are rare but important differential diagnoses of nonfunctioning pituitary masses. Primary hypophysitis as an autoimmune disorder has received increasing attention over the past decades. In the last decade, immune checkpoint inhibitor–induced hypophysitis has emerged as a new type of secondary hypophysitis. Various pituitary tumors may also cause secondary hypophysitis. Systemic, noninfectious granulomatous diseases that can involve the pituitary region include sarcoidosis, granulomatosis with polyangiitis, Langerhans cell histiocytosis, Erdheim-Chester disease, and Rosai-Dorfman disease. Furthermore, infectious diseases can affect the pituitary gland.…
Granulocytenfunktionsdefekte bei granulomat�ser muco-cutaner candidiasis
1975
Es wird uber einen 12jahrigen Jungen mit einer rezidivierenden mucocutanen Candidiasis berichtet, der an einer Cryptococcose verstarb. Bei diesem Kind wurden Defekte der unspezifischen Immunitat in Form eines Chemotaxis- und Phagocytosedefizits der polymorphkernigen Neutrophilen nachgewiesen, wahrend Immunglobuline und Komplementfaktoren sowie insbesondere die lymphocytenvermittelten Reaktionen im Normbereich lagen. Die Heterogenitat hinsichtlich der Atiopathogenese der granulomatosen muco-cutanen Candidiasis machen auch Funktionsprufungen der Granulocytenfunktionen erforderlich, zumal solche Defekte inzwischen mehrfach beobachtet wurden.
Model for Generation of Large Numbers of Primary, Inflammatory Skin-Derived Neutrophils, and Macrophages
2012
Tissue macrophages and inflammatory neutrophils represent important cells of the innate immune system responsible for various important tasks, i.e., elimination of pathogens and/or granuloma formation. Isolation of large numbers of primary phagocytes is vital for research with these cells. Within this protocol, we present a strategy for isolation of large numbers of inflammatory neutrophils and macrophages from murine skin that allows for follow-up in vivo or in vitro studies.
Granuloma piógeno en tapones lagrimales smart plug
2007
espanolCaso clinico: Mujer de 65 anos, diagnosticada de ojo seco, acude por aparicion de tumoracion en canto interno con sensacion de cuerpo extrano. Tres anos antes se le habian implantado tapones lagrimales SmartPlug en ambos puntos lagrimales inferiores. Se aprecio un granuloma en el punto lagrimal inferior izquierdo que se extirpo. Dos semanas despues presento una recidiva lo que obligo a extraer el implante quedandose desde entonces asintomatica. Discusion: Estamos ante un granuloma piogeno en un implante punctal SMART PLUG, complicacion descrita clasicamente con los implantes de silicona, debido posiblemente a la irritacion cronica de los detritus acumulados. Esta complicacion obliga …
Pioderma gangrenoso superficial como complicación de mamoplastia
2011
El Pioderma Gangrenoso (PG) es una rara enfermedad de etiología desconocida, sospechándose que pudiera ser debida a trastornos de autoinmunidad. Presentamos 2 casos de PG Granulomatoso en el postoperatorio mediato (3-6 semanas) en pacientes sometidas a mamoplastia (mastopexia con prótesis). Ambos casos se solucionaron mediante tratamiento con corticoesteroides.
A new pyrazolo pyrimidine derivative inhibitor of cyclooxygenase-2 with anti-angiogenic activity
2003
In a previous study, we reported a new pyrazolo pyrimidine derivative, N(4)-benzyl-N(6),N(6)-dimethyl-1-1(tert-butyl)-1H-pyrazolo[3,4-d]pyrimidine-6,4-diamine (DPP), which inhibited potently cyclooxygenase-2 activity in intact cell assays with minor activity against cyclooxygenase-1 (IC(50)=0.9 nM for cyclooxygenase-2 versus IC(50)=59.6 nM for cyclooxygenase-1). In the present work, this behaviour was confirmed in vivo by using the 24-h zymosan-injected mouse air pouch model (ID(50)=1.36 nM/pouch for prostaglandin E(2) level). We also studied the possible beneficial effect of DPP in the angiogenesis-dependent murine air pouch granuloma and rat paw carrageenan-induced hyperalgesia models. DP…
Queilitis granulomatosa de Miescher: presentación de cinco casos
2004
La queilitis granulomatosa de Miescher (QG), consiste en la aparición de edema labial recurrente en uno o ambos labios, el cual puede llegar a ser persistente. Ha sido considerada tradicionalmente, como una forma monosintomática del síndrome de Melkersson Rosenthal, descrito como la asociación de edema labial y/o facial recurrente, parálisis facial recidivante y lengua fisurada. El objetivo de este trabajo es presentar una serie de 5 casos diagnosticados clínica e histopatológicamente de QG, que acudieron a la consulta de la Unidad Docente de Medicina Bucal de la Universidad de Murcia. Se realizó un estudio completo de estos pacientes, valoramos la edad y el sexo, antecedentes familiares, l…
A case of bowel schistosomiasis that did not adhere to the endoscopic findings.
2005
Diagnostic techniques and multidisciplinary approach in idiopathic granulomatous mastitis: A revision of the literature
2019
Idiopathic granulomatous mastitis (IGM) is a chronic benign inflammatory disease of the breast that may mimic breast cancer. It is most common in parous young fertile women, although it can occur in nulliparous women and in men. IGM is an idiopathic disease due to the influence of some environmental factors in genetically predisposed subjects. Several pathogenic hypothesis have been proposed in the last years (autoimmune, hormonal, infective genesis). IGM presents as a painful palpable mass located in one of the two udders. The skin is usually normal but could present signs of inflammation with or without lymph nodes involvement. Ultrasonography, mammography, magnetic resonance can be diagn…
CROHN'S DISEASE AND EXTRAINTESTINAL GRANULOMATOUS LESIONS
2018
Crohn's disease (CD) is an inflammatory bowel disease with a multifactorial etiology. Clinical features include mucosal erosion, diarrhea, weight loss and other complications such as formation of granuloma. in CD, granuloma is a non-neoplastic epithelioid lesio, formed by a compact aggregate of histiocytes with the absence of a central necrosis, however, the correlation amomg CD and the formation of granulomas is unknown. Many casesof granulomas in the extracellular site, related to Cd, have been reported in the literature. These granulomas, at times, rapresented the only visible manifestation of the pathology. extra intestinal granuloma have been found on ovaries, lungs, male genitalia, fe…