Search results for "gut"
showing 10 items of 605 documents
Cities and their effects on free-living and host-associated microbes
2023
Mikrobit ovat oleellisen tärkeitä elämälle maapallolla, ja niitä esiintyy vapaina ympäristössä tai isäntäorganismeissa tukien ekosysteemien ja/tai isäntien normaalia toimintaa. Ihminen vaikuttaa lähes kaikkiin planeettamme elinympäristöihin aiheuttaen niiden häviämistä ja huonontumista (mukaan lukien kaupunkien rakentaminen) sekä ympäristöjen saastumista ja ilmastonmuutosta. Mikrobiyhteisöjen (kutsutaan myös mikrobiotaksi, mukaan lukien bakteerit ja sienet) odotetaan reagoivan näihin ihmisen aiheuttamiin valintapaineisiin sopeutumalla muuttuvaan ympäristöön. Siten ihmisen aiheuttamat muutokset ympäristössä voivat muovata mikrobiyhteisöjä (sekä vapaasti eläviä että isäntiin liittyviä) muutta…
The Metabolic Sensor GPR43 Receptor Plays a Role in the Control of Klebsiella pneumoniae Infection in the Lung
2018
Pneumonia is one of the leading causes of death and mortality worldwide. The inflammatory responses that follow respiratory infections are protective leading to pathogen clearance but can also be deleterious if unregulated. The microbiota is known to be an important protective barrier against infections, mediating both direct inhibitory effects against the potential pathogen and also regulating the immune responses contributing to a proper clearance of the pathogen and return to homeostasis. GPR43 is one receptor for acetate, a microbiota metabolite shown to induce and to regulate important immune functions. Here, we addressed the role of GPR43 signaling during pulmonary bacterial infection…
Baseline Gut Microbiota Composition Is Associated With Schistosoma mansoni Infection Burden in Rodent Models
2020
In spite of growing evidence supporting the occurrence of complex interactions between Schistosoma and gut bacteria in mice and humans, no data is yet available on whether worm-mediated changes in microbiota composition are dependent on the baseline gut microbial profile of the vertebrate host. In addition, the impact of such changes on the susceptibility to, and pathophysiology of, schistosomiasis remains largely unexplored. In this study, mice colonized with gut microbial populations from a human donor (HMA mice), as well as microbiota-wild type (WT) animals, were infected with Schistosoma mansoni, and alterations of their gut microbial profiles at 50 days post-infection were compared to …
Nuevas claves para la lectura de Cornelia Bororquia (1801)
2003
En los últimos años del siglo XVIII y principios del siglo XIX la vigencia del pensamiento éclairé fomenta un clima favorable a la supresión del Santo Oficio; la censura del Santo Tribunal es el eje central de Cornelia Bororquia o la víctima de la Inquisición (1801), novela del ex-trinitario Luis Gutiérrez que narra la indefensión de una muchacha en las cárceles de la Inquisición. La novela argumenta en favor de la tolerancia religiosa y en la línea de un cristianismo ilustrado, pero no alcanza el tono radical de otros españoles expatriados. Mientras que el exilio de José Marchena radicaliza su discurso político y su sueño de una sociedad sin clases, la vía de Luis Gutiérrez es más reformad…
Metabolomics as a Promising Resource Identifying Potential Biomarkers for Inflammatory Bowel Disease
2021
Inflammatory bowel disease (IBD) is a relapsing chronic disorder of the gastrointestinal tract characterized by disruption of epithelial barrier function and excessive immune response to gut microbiota. The lack of biomarkers providing early diagnosis or defining the status of the pathology difficulties an accurate assessment of the disease. Given the different metabolomic profiles observed in IBD patients, metabolomics may reveal prime candidates to be studied, which may help in understanding the pathology and identifying novel therapeutic targets. In this review, we summarize the most current advances describing the promising metabolites such as lipids or amino acids found through untarge…
Gutters egne refleksjoner omkring hvorfor de avsluttet videregående opplæring, og hva som skal til for å fullføre utdanning : En kvalitativ studie ba…
2018
Masteroppgave psykisk helsearbeid ME504 - Universitetet i Agder 2018 Throughout our working carrier we have met youth who had dropped out from upper secondary school with that consequence that they stand without work or education. We wish to approach the phenomenon dropouts from the perspective of the youth, here boys, to try to find out more about how they think of their own possibilities. This study is part of a research project at the University of Agder and represents a contribution to the research group “Ung i Sør”. The purpose of this study is to increase understanding around how boys explain the causes behind their choice to dropout and what they express can contribute to returning t…
New models in particle and astroparticle physics: consequences for dark matter and LHC
2013
226 páginas. Tesis Doctoral del Departamento de Física Teórica, de la Universidad de Valencia.
Dissimilar Regulation of Antimicrobial Proteins in the Midgut of Spodoptera exigua Larvae Challenged with Bacillus thuringiensis Toxins or Baculoviru…
2015
Antimicrobial peptides (AMPs) and lysozymes are the main effectors of the insect immune system, and they are involved in both local and systemic responses. Among local responses, midgut immune reaction plays an important role in fighting pathogens that reach the insect body through the oral route, as do many microorganisms used in pest control. Under this point of view, understanding how insects defend themselves locally during the first phases of infections caused by food-borne pathogens is important to further improve microbial control strategies. In the present study, we analyzed the transcriptional response of AMPs and lysozymes in the midgut of Spodoptera exigua (Lepidoptera: Noctuidae…
Individual differences in behavioral consistency are related to sequential access to resources and body condition in a producer-scrounger game
2014
Investigating the evolution of consistent between-individual behavioral differences necessitates to explain the emergence of within-individual consistency. Relying on a recent mathematical model, we here test the prediction that the emergence of differences in within-individual consistency is related to the sequential access to resources in a frequency-dependent foraging game. To this end we used flocks of zebra finches (Taeniopygia guttata) engaged in a producer-scrounger foraging game. Tactic investment (i.e., the proportion of hops with the head down) significantly predicted successful tactic use (i.e., the proportion of seeds produced). In support of predictions, we found that individua…
Data from: Pairing context determines condition-dependence of song rate in a monogamous passerine bird
2013
Condition-dependence of male ornaments is thought to provide honest signals on which females can base their sexual choice for genetic quality. Recent studies show that condition-dependence patterns can vary within populations. Although long-term association is thought to promote honest signalling, no study has explored the influence of pairing context on the condition-dependence of male ornaments. In this study, we assessed the influence of natural variation in body condition on song rate in zebra finches (Taeniopygia guttata) in three different situations: during short and long encounters with an unfamiliar female, and within heterosexual mated pairs. We found consistent individual differe…