Search results for "hardware"
showing 10 items of 1372 documents
From microbial proteomics to synthetic biology: Amycolatopsis balhimycina case
2012
Actinomycetes, filamentous Gram-positive bacteria, are usually exploited as bio-farms naturally producing a wide range of small biologically active metabolites, such as antibiotics, extensively used in medicine, food-industry, chemistry and bio-remediation strategies. The development of high throughput technologies, like proteomics, allows functional genomic studies aimed at shedding light on molecular mechanisms controlling the production of useful compounds and macromolecules. Differential proteomic analyses, performed by using Two Dimensional PolyAcrylamide Gel Electrophoresis (2D-PAGE) coupled to mass spectrometry (MS) procedures, revealed novel links between balhimycin production (a va…
Drying kinetics and physico-chemical quality of mango slices
2019
Mango (Mangifera indica L.) is an important tropical fruit consumed worldwide and grown in Italy only in Sicily, where the areas of the Tyrrhenian coast have proved to be suitable to produce valuable fruits. Mango fruit has a pleasant aroma and taste, which are important qualities for consumer’s sensorial acceptance. However, they are highly perishable, prone to progressive undesired changes if stored untreated, resulting in around 25% postharvest losses, which is further increased during storage and transportation. An alternative for reducing the above-mentioned undesired changes is the dehydration of the cut fruit, which reduce the fruit water activity, thereby avoiding the deteriorative …
Graphene nanosystems as supports in siRNA Delivery
2018
The nature of graphene-based nanosystems, as well as the possibility to synthesize them at low cost, have made them in the last few years, an interesting proposition in tumour therapy as a drug delivery system. Here, a reduced form of graphene oxide (RGO) has been synthesized and conjugated with a specific antibody for active targeting against tumour cells (RGOY). Furthermore, its bi-dimensional nature permits also p- p stacking interactions with planar molecules like siRNA (RGOY-siRNA). All these nano-complexes were characterized by DLS and DSC analysis, TEM and Raman spectroscopy and their biocompatibility was demonstrated by viability assay on cell line ECV 304. The system is able to be …
Formulation of Different Chitosan Hydrogels for Cartilage Tissue Repair
2014
Different formulations of Chitosan/sulphate and Chitosan/PEGDE were produced by physical and chemical reticulation to obtain hydrogels with better physiochemical properties. The hydrogels were analyzed – in terms of their non-toxicity, proliferative, differentiative, inflammatory and immunology responses. Commercial grade Chitosan (Sigma) was solubilized and purified by progressive filtrations. Then, the polymer was freeze-dried in a water soluble cationic form. A physical hydrogel was prepared by mixing a 3 % w/w water solution of the a.m. polymer with different stoichiometric ratios of (SO4=) 1/0.5;1/0.75;1/1 respectively. The hydrogels were cross-linked in multiwells. The chemical hydrog…
Fabrication and characterization of nanostructured Ni and Pd electrodes for hydrogen evolution reaction (HER) in water-alkaline electrolyzer
2017
In the field of water-alkaline electrolyzer, the development of nanoporous low cost nickel electrodes is one of the potential approaches to increase electrocatalytic activity. Template electrodeposition is a facile and cheap technique for obtaining Ni nanowires (NWs) with high surface area. These nanostructures were fabricated by a two-step procedure. In the first step, a Ni compact layer was deposited on one side of the template where a gold film was previously sputtered, while, in the second-step, an ordered array of Ni-NWs was obtained by electrodeposition inside the template channels. The NWs were firmly connected to the underlying Ni layer, acting as a current collector. In order to en…
Growth and Electrochemical Performance of Lead and Lead Oxide Nanowire Arrays as Electrodes for Lead-Acid Batteries
2013
n this work, we present the growth and electrochemical performance of nanostructured lead and lead oxide electrodes for lead-acid batteries. The electrodes were obtained by template electrodeposition in polycarbonate membranes, acting as template. Electrochemical tests were conducted at constant current in 5M aqueous solution of sulphuric acid, after assembling nanostructured lead and lead oxide electrodes in a zero-gap configuration using a commercially available separator. The main advantages of these electrodes are the high specific energy and power density, and the wide surface area, about 70 times higher than the geometrical one. These features allowed high discharge rates, up to 20C. …
Hold-in, Pull-in and Lock-in Ranges for Phase-locked Loop with Tangential Characteristic of the Phase Detector
2019
In the present paper the phase-locked loop (PLL), an electric circuit widely used in telecommunications and computer architectures is considered. A new modification of the PLL with tangential phase detector characteristic and active proportionally-integrating (PI) filter is introduced. Hold-in, pull-in and lock-in ranges for given circuit are studied rigorously. It is shown that lock-in range of the new PLL model is infinite, compared to the finite lock-in range of the classical PLL. peerReviewed
Design and simulation of QCA-based 3-bit binary to gray and vice versa code converter in reversible and non-reversible mode
2022
The current Very Large-Scale Integration (VLSI) technology has reached its peak due to the fundamental physical limits of Complementary Metal-Oxide-Semiconductor (CMOS). Quantum-dot Cellular Automata (QCA) is considered a proper alternative to CMOS technology in digital circuit design. QCA has features like low power, small area, and high speed in nanoscale digital circuit design. A code converter is a circuit that converts a determined code to another one. Code converters such as Binary to Gray, Gray to Binary, and Binary to BCD converters have a crucial role in fast signal processing in digital systems. Also, code converters are used as a base unit for data transmission into the Arithmeti…
New Capabilities of the FLUKA Multi-Purpose Code
2022
We would like to deeply thank the CERN Knowledge Transfer and Legal Service teams for their essential and extended support. Our appreciation also goes to the FLUKA.CERN Collaboration Board members for their strong commitment.
A virtual reality system for the treatment of stress-related disorders: A preliminary analysis of efficacy compared to a standard cognitive behaviora…
2011
This paper presents preliminary efficacy data in a controlled study of the use of a virtual reality (VR) system for treating stress-related disorders (Post-Traumatic Stress Disorder, or PTSD; Pathological Grief, or PG; and Adjustment Disorders, or AD). ''EMMA's World'' is a VR application in which patients can explore negative experiences to the degree required for their specific therapeutic needs. To accomplish therapeutic goals, a series of virtual elements is customized to be meaningful to the user; the elements contain the fundamental emotional components that the person must confront. Thirty-nine participants diagnosed with PTSD (N=10), PG (N=16), and AD (N=13) were randomly assigned t…