Search results for "hbv"
showing 5 items of 95 documents
Hepatitis B virus in diabetic patients
1980
The presence of HBV markers was determined in 149 serum samples obtained from diabetic patients and was compared with a normal population. Diabetics have the same incidence of HBsAg but significantly higher anti-HBc antibodies. These differences were seen in the group of diabetics on oral hypoglycemic therapy. These results cannot yet be explained.
Isolated Anti-HBc: Significance and Management.
2019
Hepatitis B virus (HBV) infection is prevalent worldwide and is associated with dramatic levels of morbidity and mortality. Isolated anti-HBc (IAHBc) is a particular serological pattern that is commonly found in immunocompromised patients. There is ongoing debate regarding the management of patients with IAHBc. Herein, we summarize the current guidelines and the newest evidence. The frequency of IAHBc is variable, with a higher prevalence in some populations, such as persons living with HIV and others immunocompromised patients. The risk of HBV reactivation depends on host factors (including immunosuppression) and viral factors. It is now well established that immunocompromised patients can…
Recommendations for the prevention, diagnosis, and treatment of chronic hepatitis B and C in special population groups (migrants, intravenous drug us…
2011
Abstract The global spread of hepatitis B virus (HBV) and hepatitis C virus (HCV), their high chronicity rates and their progression to cirrhosis and hepatocellular carcinoma, are major public health problems. Research and intervention programmes for special population groups are needed in order to assess their infection risk and set up suitable prevention and control strategies. Aim of this paper is to give health care professionals information on HBV and HCV infections amongst migrants, drug users and prison inmates. The manuscript is an official Position Paper on behalf of the following Scientific Societies: Italian Association for the Study of the Liver (A.I.S.F.), Italian Society of In…
Cilvēka nātrija tauroholāta ko-transportējoša polipeptīda klonēšana un ekspresija zīdītāju šūnās
2015
Neskatoties uz to, ka ir izstrādāta droša un efektīva hepatīta B vakcīna, kā arī vesela rinda pret hepatīta B vīrusu (HBV) vērstu ķīmisku līdzekļu, pasaulē ir >350 miljonu hronisko HBV nēsātāju, no kuriem 1 miljons mirst katru gadu. Galvenais jaunu terapijas veidu izstrādāšanas kavēklis ir efektīvas HBV infekciju un replikāciju nodrošinošas in vitro modeļsistēmas trūkums. Pateicoties revolucionāram atklājumam par NTCP (sodium taurocholate cotransporting peptide) lomu HBV infekcijas procesā pašlaik tiek aktīvi izstrādātās jaunās HBV in vitro infekcijas modeļsistēmas. Mūsu darbā NTCP receptoru ekspresējošo šūnu iegūšanai tika izmantota efektīva Semliki Meža vīrusa (SFV) replikona ekspresijas …
Thermal and thermo-oxidative stability and kinetics of decomposition of PHBV/sisal composites
2017
The decomposition behaviours of composites made of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) and sisal were assessed in terms of thermal stability and decomposition kinetics, under inert and oxidative conditions, by means of multi-rate linear non-isothermal thermogravimetric experiments. A statistical design of experiments was applied to study the influence of the addition of sisal (0-10-20-30%wt), the presence coupling agent (Yes/No) and the applied conditions of work (inert or oxidative). An improvement of the thermal and thermo-oxidative stability of PHBV with the addition of sisal was observed for all cases. An accurate methodology based on iso-conversional methods was applied…