Search results for "health care facilities"
showing 10 items of 163 documents
Colorectal Cancer in Elderly Patients: From Best Supportive Care to Cure
2013
Colorectal cancer is one of the major causes of cancer mortality in the elderly population (median age at diagnosis of 71 years) in Western Countries. Moreover patients with metastatic disease are often elderly with significant co- morbidities. Unfortunately, elderly patients are often untreated and under-represented in clinical trials, even if most clinical trials that have included this setting of population have shown similar survival rates and toxicities to younger patients. Age itself should not be considered for candidacy to chemotherapy but it should be taken in consideration the great heterogeneity of co-morbidities present in the elderly population. Therefore, the best treatment st…
Hospital and outpatient models for Hematopoietic Stem Cell Transplantation: A systematic review of comparative studies for health outcomes, experienc…
2021
The number of Hematopoietic Stem Cell Transplantations has risen in the past 20 years. The practice of outpatient Hematopoietic Stem Cell Transplantation programs is increasing in an attempt to improve the quality of patient care and reduce the demand for hospital admission. A systematic review of 29 comparative studies between in-hospital and outpatient treatment of Hematopoietic Stem Cell Transplantation, with no restriction by outpatient regime was conducted. This study aims to analyse the current evidence on the effects of the outpatient model on patient-centred outcomes, comparing both in-hospital and outpatient models for autologous and allogeneic HSCT using the Triple Aim framework: …
Prevalence of burnout in a sample of Brazilian teachers
2011
Background and Objectives: Burnout is a psychological response to chronic work-related stress of an interpersonal and emotional nature. Brazilian law have already contemplated burnout syndrome as a mental and behavioural disorder related to work. The aim of this study was to identify the prevalence of burnout in a sample of Brazilian teachers. Methods: The sample was composed of 714 teachers from 8 schools in Porto Alegre and its metropolitan area (Brazil). The levels of burnout were evaluated by the Spanish Burnout Inventory, educational version (SBI-Ed). In addition, Psychosomatic disorders were estimated by the UNIPSICO subscale. Results: The percentage of participants who indicated high…
Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics
2021
To date, computational approaches have been recognized as a key component in drug design and discovery workflows. Developed to help researchers save time and reduce costs, several computational tools have been developed and implemented in the last twenty years. At present, they are routinely used to identify a therapeutic target, understand ligand–protein and protein–protein interactions, and identify orthosteric and allosteric binding sites, but their primary use remains the identification of hits through ligand-based and structure-based virtual screening and the optimization of lead compounds, followed by the estimation of the binding free energy. The repurposing of an old drug for the tr…
Pheromone-induced odour learning in newborn rabbits: action, development and adaptive function
2012
Communication orale; International audience
The mediating role of feelings of guilt in the relationship between burnout and the consumption of tobacco and alcohol
2014
Earlier studies have shown that feelings of guilt appear to be involved in the burnout process. However, the exact nature of the relationship between burnout, feelings of guilt, and tobacco and alcohol use is unclear. The purpose of this study was to analyze the role of feelings of guilt in the relationship between burnout and the consumption of tobacco and alcohol. Role conflict, Role clarity, and Feedback were included as predictors of burnout. The sample of this cross-sectional study consisted of 260 Chilean administration and customer service workers. Hypotheses were tested using a path model. The hypothesized model (i.e., Indolence to guilt to tobacco/alcohol use) showed an adequate da…
Internal Public Audit in the Financial Crisis Context
2013
Abstract The financial crisis effects have left their mark on the area of internal audit, but the attention on the responsibility that internal auditors could have in preventing the onset of such a crisis is quite low. Audit plays a vital role in the entities functioning by contributing to economic credibility. In this paper we have presented the role and objectives of internal audit, the organization and activity of internal audit in local government in Romania, the outsourced system and how it helped in preventing and/or managing the economic downturn.
Development of School and Sport Burnout in Adolescent Student-Athletes: A Longitudinal Mixed-Methods Study.
2018
We investigated the development of school and sport burnout in adolescent student-athletes (N Time 1 = 391, N Time 2 = 373) during their first year in upper secondary school using an embedded mixed-methods design. The questionnaire-based data were analyzed with growth mixture modeling and four burnout profiles were identified among student-athletes. From the found burnout profiles, two were typical for the interviewed subsample of elite athletes (n = 17), that is, burnout risk and non risk profiles. We generated rich descriptions of well-being and ill-being, showing that elite athletes in two burnout profiles differed in their experienced demands and resources related to individual and envi…
The short-term efficacy and safety of artificial total disc replacement for selected patients with lumbar degenerative disc disease compared with ant…
2018
PurposeTo systematically compare the efficacy and safety of lumbar total disc replacement (TDR) with the efficacy and safety of anterior lumbar interbody fusion (ALIF) for the treatment of lumbar degenerative disc disease (LDDD).MethodsThe electronic databases PubMed, Web of Science and the Cochrane Library were searched for the period from the establishment of the databases to March 2018. The peer-reviewed articles that investigate the safety and efficacy of TDR and ALIF were retrieved under the given search terms. Quality assessment must be done independently by two authors according to each item of criterion. The statistical analyses were performed using RevMan (version 5.3) and Stata (v…
Relationships between burnout and role ambiguity, role conflict and employee absenteeism among health workers
2014
The aim of this research was to analyze the influence of some psychosocial risk factors in the development of burnout and to analyze the influence of this phenomenon on employee absenteeism. The study sample included 142 health care workers. The data analysis included descriptive statistics and multiple linear regression models. The results confirmed the influence of role ambiguity and role conflict on burnout [F (2.139) = 26.720; p < .001], but the influence of burnout on employee absenteeism was not confirmed. However, a significant and positive relationship has been shown between burnout and employee absenteeism (β = 0.197; p < .05). In conclusion, the findings of this study support the …