Search results for "help"

Approximation problems in linear and non-linear analysis

2023

En esta tesis estudiamos problemas relacionados con aplicaciones de varios tipos que alcanzan su norma u operadores que alcanzan su radio numérico. Tras un capítulo introductorio donde se comentan las notaciones, los principales conceptos, y un resumen histórico del estado del arte, hay 4 capítulos de contenido matemático donde se estudian diversos tipos de problemas. En el capítulo 2, se estudian clases de operadores entre espacios de Banach tales que cuando casi alcanzan su norma (respectivamente, su radio numérico) en un punto (respectivamente, un estado), necesariamente la alcanzan en un punto cercano (respectivamente, en un estado cercano). Se obtienen resultados positivos para dominio…

Fostering brand engagement and value-laden trusted B2B relationships through digital content marketing

2019

Purpose The purpose of this paper is to explore how digital content marketing (DCM) users can be engaged with business-to-business (B2B) brands and determine how such engagement leads to value-laden trusted brand relationships. Design/methodology/approach Through an online survey, data were collected from the email marketing list of a large B2B brand, and the hypothesised research model was analysed using covariance-based structural equation modelling. Findings This paper identifies a bundle of helpful brand actions – providing relevant topics and ideas; approaching content with a problem solving orientation; as well as investing in efforts to interpret, analyse and explain topics through …

CXCR5 identifies a subset of Vgamma9 Vdelta2 T cells which secrete IL-4 and IL-10 and help B cells for antibody production.

2006

Vgamma9Vdelta2 T lymphocytes recognize nonpeptidic Ags and mount effector functions in cellular immune responses against microorganisms and tumors, but little is known about their role in Ab-mediated immune responses. We show here that expression of CXCR5 identifies a unique subset of Vgamma9Vdelta2 T cells which express the costimulatory molecules ICOS and CD40L, secrete IL-2, IL-4, and IL-10 and help B cells for Ab production. These properties portray CXCR5+ Vgamma9Vdelta2 T cells as a distinct memory T cell subset with B cell helper function.

Modification of the immune response against hepatitis B virus by the human immunodeficiency virus.

1989

Hepatitis B virus and the human immunodeficiency virus are similarly transmitted. Individuals with preexisting HIV infection have a higher chance to become HBsAg carriers than do anti-HIV negative persons. Cytotoxic T cells with specificity for HBcAg, that are under the control of HBcAg-specific helper T cells, are responsible for liver injury. There is good evidence that HIV infection lowers inflammatory activity, is associated with milder liver histology, high levels of viral replication and low seroconversion rates. In addition interferon alpha therapy is less effective in anti-HIV positive subjects. The immune response against HBsAg is helper T-cell dependent and vaccination against hep…

Hypoxia Positively Regulates the Expression of pH-Sensing G-Protein–Coupled Receptor OGR1 (GPR68)

2016

Background & Aims: A novel family of proton-sensing G-proteinâcoupled receptors, including ovarian cancer G-proteinâcoupled receptor 1 (OGR1) (GPR68) has been identified to play a role in pH homeostasis. Hypoxia is known to change tissue pH as a result of anaerobic glucose metabolism through the stabilization of hypoxia-inducible factor-1α. We investigated how hypoxia regulates the expression of OGR1 in the intestinal mucosa and associated cells. Methods: OGR1 expression in murine tumors, human colonic tissue, and myeloid cells was determined by quantitative reverse-transcription polymerase chain reaction. The influence of hypoxia on OGR1 expression was studied in monocytes/macrophages and…

Influence of type III bacterial secretion system on the interactions between plant and non pathogenic fluorescent Pseudomonads spp.

2010

No abstract

Interactions between a mycorrhiza helper bacterium and arbuscular mycorrhizas

2009

Pseudomonas fluorescens C7R12 was shown to promote arbuscular mycorrhization and to act as a ‘Mycorrhiza Helper Bacteria’ (MHB). The complex interactions between this model strain, Arbuscular Mycorrhizal (AM) fungi and host-plants were analysed by assessing the specificity of these interactions and by characterizing bacterial cell organization on mycorrhizal roots. Evaluation of the interaction specificity relied on the comparison of the bacterial effect on (i) the in vitro saprophytic growth of Glomus mosseae and Gigasopora rosea and (ii) the root colonization of two different plant species (Medicago truncatula and Lycopersicon esculentum) by the two AM fungal species. Characterization of …

Influence du système de sécrétion de type III bactérien dans les intéractions plantes-Pseudomonas spp. fluorescents non pathogènes

2012

http://prodinra.inra.fr/record/271693SPEEAEcolDurCT3; L’objectif de cette thèse a été de contribuer à faire progresser les connaissances sur les interactions bénéfiques entre les plantes et les microorganismes en évaluant la contribution des systèmes de sécrétion de type III (SST3). Une synthèse des connaissances disponibles relatives aux SST3 chez les Pseudomonas non pathogènes, saprotrophes ou mutualistes, montre que les SST3 ne sont pas cantonnés aux interactions parasites ou pathogènes avec les plantes. Dans la première étude expérimentale, nous avons utilisé différents génotypes de Medicago truncatula Gaertn. cv. Jemalong capables (Myc+) ou non (Myc-) d’établir une symbiose mycorhizien…

Analysis of virtual helps usage in a virtual environment for learning

2007

Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression.

2008

Background & Aims Foxp3-expressing regulatory T cells (Tregs) play a key role in the maintenance of the gut immune homeostasis, and an intact transforming growth factor (TGF)-β signaling is required for their function. In inflammatory bowel disease (IBD), the TGF-β signaling is impaired because of high expression of the inhibitory molecule Smad7. Although no intrinsic defects in Tregs function have been shown in IBD, it is still unknown whether colitogenic T cells are susceptible to Treg-mediated suppression. In this study, we have investigated whether IBD mucosal CD4+ T cells are resistant to Tregs and whether Smad7 is involved in this process. Methods IBD lamina propria mononuclear cells …