Search results for "hemoglobiini"
showing 5 items of 5 documents
Aptamer-embedded DNA origami cage for detecting (glycated) hemoglobin with a surface plasmon resonance sensor
2020
DNA origami-based cages functionalized with aptamer motifs, were used to detect hemoglobin and glycated hemoglobin. The binding between the cages and hemoglobin was monitored using a surface plasmon resonance (SPR) sensor. One DNA strand in the nano-cage was replaced with an aptamer that demonstrated a high affinity to hemoglobin (Hb) or glycated hemoglobin (gHb). Three types of the DNA nano-cages designed to fit the size and shape of hemoglobin were evaluated: one without an aptamer, one with the Hb-affinity aptamer (HA) and one with the gHb-affinity aptamer (GHA). Both DNA nano-cages embedded with HA and GHA showed significantly more stable binding with Hb and gHb by 5 and 9 times, respec…
Haemoglobin, iron status and lung function of adolescents participating in organised sports in the Finnish Health Promoting Sports Club Study
2020
ObjectivesTo compare laboratory test results and lung function of adolescent organised sports participants (SP) with non-participants (NP).MethodsIn this cross-sectional study, laboratory tests (haemoglobin, iron status), and flow-volume spirometry were performed on SP youths (199 boys, 203 girls) and their NP peers (62 boys, 114 girls) aged 14–17.ResultsHaemoglobin concentration <120/130 g/L was found in 5.8% of SP and 5.1% NP (OR 1.20, 95% CI 0.54 to 2.68). Ferritin concentration below 15 µg/L was found in 22.7% of both SP and NP girls. Among boys ferritin <30 µg/L was found in 26.5% of SP and 30.2% of NP (OR 0.76, 95% CI 0.40 to 1.47). Among SP iron supplement use was reported by 3…
VHb-siirtogeenin vaikutukset geenimuunnellun nieriän (Salvelinus alpinus) hapenkulutukseen ja kasvuun
2012
Nieriä (Salvelinus alpinus) on arvostettu laji sekä urheilukalastuksessa että ruokakalana. Vähentyneiden populaatioiden ja viljelyssä havaittujen ongelmien takia sitä ei kuitenkaan Suomessa voida taloudellisesti hyödyntää parhaalla mahdollisella tavalla. Ilmastonmuutos voi hankaloittaa ennestään nieriän viljelyä, sillä se on kylmän veden laji. Tulevaisuudessa voi siirtogeenisten lajien käyttö ruokakalana olla mahdollista niiden uusien ominaisuuksien ja tehokkaamman viljelyn takia. Tässä tutkimuksessa selvitettiin miten bakteerihemoglobiinia (VHb) koodaava VHb-siirtogeeni vaikuttaa nieriän hapenkulutukseen ja kasvuun. Geenin vaikutuksia tutkittiin mittaamalla kalojen hapenkulutusta kolmessa …
Hemoglobin mass and performance responses during 4 weeks of normobaric “live high–train low and high”
2023
Purpose To investigate whether 4 weeks of normobaric “live high–train low and high” (LHTLH) causes different hematological, cardiorespiratory, and sea-level performance changes compared to living and training in normoxia during a preparation season. Methods Nineteen (13 women, 6 men) cross-country skiers competing at the national or international level completed a 28-day period (∼18 h day−1) of LHTLH in normobaric hypoxia of ∼2400 m (LHTLH group) including two 1 h low-intensity training sessions per week in normobaric hypoxia of 2500 m while continuing their normal training program in normoxia. Hemoglobin mass (Hbmass) was assessed using a carbon monoxide rebreathing method. Time to exhaust…
Impact of Energy Availability, Health and Sex on Hemoglobin Mass Responses Following Live-High–Train-High Altitude Training in Elite Female and Male …
2018
Purpose: The authors investigated the effects of sex, energy availability (EA), and health status on the change in hemoglobin mass (ΔHbmass) in elite endurance athletes over ∼3–4 wk of live-high–train-high altitude training in Flagstaff, AZ (2135 m; n = 27 women; n = 21 men; 27% 2016 Olympians). Methods: Precamp and postcamp Hbmass (optimized carbon monoxide rebreathing method) and iron status were measured, EA was estimated via food and training logs, and a Low Energy Availability in Females Questionnaire (LEAFQ) and a general injury/illness questionnaire were completed. Hypoxic exposure (h) was calculated with low (600 h) groupings. Results: Absolute and relative percentage ΔHbmass was si…