Search results for "herb"
showing 10 items of 856 documents
P-glycoprotein and its inhibition in tumors by phytochemicals derived from Chinese herbs
2011
P-glycoprotein belongs to the family of ATP-binding cassette (ABC) transporters. It functions in cellular detoxification, pumping a wide range of xenobiotic compounds, including anticancer drugs out of the cell. In cancerous cells, P-glycoprotein confers resistance to a broad spectrum of anticancer agents, a phenomenon termed multidrug resistance. An attractive strategy for overcoming multidrug resistance is to block the transport function of P-glycoprotein and thus increase intracellular concentrations of anticancer drugs to lethal levels. Efforts to identify P-glycoprotein inhibitors have led to numerous candidates, none of which have passed clinical trials with cancer patients due to the…
New Eudesmanolides Related to Torrentin from Artemisia herba-alba subsp. valentina.
1991
The reinvestigation of aerial parts of A. herba- alba subsp. valentina afforded four new eudesmanolides, all of them closely related to torrentin. Their structures were deduced by spectroscopic and chemical methods
Toxicities by herbal medicines with emphasis to traditional Chinese medicine.
2011
It is estimated that three quarters of the world population rely on herbal and traditional medicine as a basis for primary health care. Therefore, it is one of the most important and challenging tasks for scientists working in drug research to investigate the efficacy of herbal medicine, to dissect favorable from adverse effects, to identify active principles in medicinal plants and to ban poisonous plants or contaminations from herbal mixtures. In the present review, some problems are critically discussed. Botanical misidentification or mislabeling of plant material can play a role for toxic reactions in humans. Some plant descriptions in traditional herbal medicine (e.g. traditional Chine…
The cool Galactic R Coronae Borealis variable DY Persei
2005
Results of first CCD photometry during the recent deep light decline, and high-resolution spectroscopy, are presented for DY Persei. The spectra show variable blueshifted features in the sodium D lines. The C lines are strong whereas neutron- capture elements are not enhanced. The isotopic 13 CN(2, 0) lines relative to 12 CN are of similar strength with those for the carbon star U Hya. All these confirm the RCB nature of DY Per and the existence of ejected clouds. At least two clouds are revealed at −197.3 and −143.0 km s −1 . A star was detected about 0. 4t o the west and 2 . 5 to the north from DY Per. This anonymous companion, with observed colour indices (B − V) = 0.68 and (V − R) � 1…
Quantum dots functionalised artificial peptides bioinspired to the D1 protein from the Photosystem II of Chlamydomonas reinhardtii for endocrine disr…
2021
Herein we describe the design and synthesis of novel artificial peptides mimicking the plastoquinone binding niche of the D1 protein from the green photosynthetic alga Chlamydomonas reinhardtii, also able to bind herbicides. In particular, molecular dynamics (MD) simulations were performed to model in silico the behaviour of three peptides, D1Pep70-H, D1Pep70-S264K and D1Pep70-S268C, as genetic variants with different affinity towards the photosynthetic herbicide atrazine. Then the photosynthetic peptides were functionalised with quantum dots for the development of a hybrid optosensor for the detection of atrazine, one of the most employed herbicides for weed control in agriculture as well …
Classification of Primula sect. Auricula (Primulaceae) based on two molecular data sets (ITS, AFLPs), morphology and geographical distribution
2004
On the basis of the study of c. 1100 herbarium specimens, field observations and molecular (ITS, AFLPs) evidence, Primula sect. Auricula is classified into two subsections, 25 species and six subspecies. Primula auricula L. ssp. widmerae (Pax) L. B. Zhang stat. nov., P. auricula Linn. ssp. tatriaca L. B. Zhang ssp. nov., and P. latifolia Lapeyr. ssp. cynoglossifolia (Widmer) L. B. Zhang stat. nov. are newly described or combined; P. auricula s.l. is divided into two species: P. auricula Linn. and P. balbisii Lehm., representing the northern and the southern populations of P. auricula s.l. resolved in the molecular study, respectively; P. cottia Widmer and P. balbisii Lehm. are recovered fro…
Empirical determination of Einstein A-coefficient ratios of bright [Fe II] lines
2014
The Einstein spontaneous rates (A-coefficients) of Fe+ lines have been computed by several authors with results that differ from each other by up to 40%. Consequently, models for line emissivities suffer from uncertainties that in turn affect the determination of the physical conditions at the base of line excitation. We provide an empirical determination of the A-coefficient ratios of bright [Fe II] lines that would represent both a valid benchmark for theoretical computations and a reference for the physical interpretation of the observed lines. With the ESO-Very Large Telescope X-shooter instrument between 3000 Å and 24700 Å, we obtained a spectrum of the bright Herbig-Haro object HH 1. …
Generation of radiative knots in a randomly pulsed protostellar jet. II. X-ray emission
2010
Protostellar jets are known to emit in a wide range of bands, from radio to IR to optical bands, and to date also about ten X-ray emitting jets have been detected, with a rate of discovery of about one per year. We aim at investigating the mechanism leading to the X-ray emission detected in protostellar jets and at constraining the physical parameters that describe the jet/ambient interaction by comparing our model predictions with observations. We perform 2D axisymmetric hydrodynamic simulations of the interaction between a supersonic jet and the ambient. The jet is described as a train of plasma blobs randomly ejected by the stellar source along the jet axis. We explore the parameter spac…
X-RAY EMISSION FROM PROTOSTELLAR JET HH 154: THE FIRST EVIDENCE OF A DIAMOND SHOCK?
2011
X-ray emission from about ten protostellar jets has been discovered and it appears as a feature common to the most energetic jets. Although X-ray emission seems to originate from shocks internal to jets, the mechanism forming these shocks remains controversial. One of the best studied X-ray jet is HH 154 that has been observed by Chandra over a time base of about 10 years. We analyze the Chandra observations of HH 154 by investigating the evolution of its X-ray source. We show that the X-ray emission consists of a bright stationary component and a faint elongated component. We interpret the observations by developing a hydrodynamic model describing a protostellar jet originating from a nozz…
The Complex Morphology of the X-ray and Optical Emission from HH 154: The Pulsed Jet Scenario
2009
We study the optical and X-ray emission from protostellar jets, focusing, in particular, on the case of HH 154. This project consists of two different and complementary approaches: the development of hydrodynamical models of the jet/ambient interaction, and the analysis of multi-wavelength observations. Comparing the results derived from the simulations with the observations we can infer the physical mechanisms leading to the complex morphology of the X-rays source observed at the base of HH 154.