Search results for "hole"

showing 10 items of 2900 documents

P2‐220: Cholesterol and amyloid‐beta: Evidence for a cross‐talk between astrocytes and neuronal cells

2011

medicine.medical_specialtybiologyEpidemiologyAmyloid betaChemistryCholesterolHealth PolicyPsychiatry and Mental healthCellular and Molecular Neurosciencechemistry.chemical_compoundEndocrinologyDevelopmental NeuroscienceInternal medicinebiology.proteinmedicineNeurology (clinical)Geriatrics and GerontologyAlzheimer's & Dementia
researchProduct

ATHEROSCLEROSIS AND MARKERS OF INFLAMMATION IN PATIENTS WITH METABOLIC SYNDROME

2005

medicine.medical_specialtybiologybusiness.industryC-reactive proteinInflammationFibrinogenmedicine.diseaseTunica intimamedicine.anatomical_structureInternal medicineImmunologyInternal Medicinemedicinebiology.proteinCardiologyIn patientMyocardial infarctionmedicine.symptomMetabolic syndromebusinessNational Cholesterol Education Programmedicine.drug
researchProduct

Vascular atherosclerotic disease: evaluation of the whole-blood filterability and red cell membrane microrheological pattern after intravenous admini…

1990

SummaryA study was carried out in 10 patients with vascular atherosclerotic disease to investigate the effects of a single dose of 300 mg pentoxifylline, given by intravenous infusion over 30 minutes, on various macrorheological and nzicrorheological parameters. Measurements were made at baseline, at the end of the intravenous infusion and again 30 minutes later of whole-blood filterability, erythrocyte membrane fluidity (using pyrene as probe) and transverse fluidity gradient (using fluorescent fatty acids as probes). The results showed that there was a significant variation in whole-blood filterability and the red cell membrane fluidity gradient after pentoxifylline. No difference, howeve…

medicine.medical_specialtybusiness.industryArteriosclerosisMembrane FluidityErythrocyte MembraneAtherosclerotic diseaseGeneral MedicinePharmacologyMiddle AgedBlood ViscosityRed cell membraneSurgeryPentoxifyllineErythrocyte membraneErythrocyte DeformabilityInjections IntravenousmedicineMembrane fluidityHumansPentoxifyllinebusinessRheologymedicine.drugWhole bloodAgedCurrent medical research and opinion
researchProduct

Response to treatment and occurrence of cardiovascular (CV) complications in patients with autosomal recessive hypercholesterolemia (ARH): A retrospe…

2016

medicine.medical_specialtybusiness.industryAutosomal Recessive HypercholesterolemiaInternal medicineRetrospective analysisMedicineIn patientCardiology and Cardiovascular MedicinebusinessResponse to treatmentSurgeryAtherosclerosis
researchProduct

The prevalence of cardiovascular risk factors and cardiovascular disease among primary care patients in Poland: results from the LIPIDOGRAM2015 study

2020

Abstract Background Cardiovascular disease (CVD) is currently one of the leading cause of mortality in the European Union. Well-established, modifiable cardiovascular (CV) risk factors include hypertension (HTN), hypercholesterolaemia, diabetes mellitus (DM), obesity, low activity levels, poor diet and smoking. There are no current estimates on the prevalence of CV risk factors among Polish patients solely in the primary care setting. Methods A nationwide cross-sectional study, LIPIDOGRAM2015, was carried out in Poland in the 4th quarter of 2015 and 1st and 2nd quarters of 2016. 438 primary care physicians enrolled 13,724 adult patients that sought medical care for any medical reason in pri…

medicine.medical_specialtybusiness.industryCholesterolDiseaseOverweightmedicine.diseaseObesitychemistry.chemical_compoundBlood pressurechemistryDiabetes mellitusInternal medicineEpidemiologymedicinemedia_common.cataloged_instancemedicine.symptomEuropean unionCardiology and Cardiovascular Medicinebusinessmedia_commonEuropean Heart Journal
researchProduct

2214Prevalence and severity of coronary disease in patients with familial hypercholesterolemia hospitalized for an acute myocardial infarction: data …

2019

Abstract Aim Individuals with heterozygous familial hypercholesterolemia (FH) are at high risk of early myocardial infarction (MI). However, coronary artery disease (CAD) burden of FH remains not well described. From a large database of a regional registry of acute MI, we aimed to address prevalence of FH and severity of CAD. Methods Consecutive patients hospitalized with MI in a multicentre database from 2001–2017 were considered. An algorithm, adapted from Dutch Lipid Clinic Network criteria, was built upon 4 variables (LDL-cholesterol (LDL-C) and lipid lowering agents, premature and family history of CAD) to identify FH probabilities. Results Among the 11624 patients included in the surv…

medicine.medical_specialtybusiness.industryCoronary arteriosclerosisFamilial hypercholesterolemiaCoronary diseasemedicine.diseaseEzetimibeInternal medicineDiabetes mellitusEpidemiologymedicineIn patientMyocardial infarctionCardiology and Cardiovascular Medicinebusinessmedicine.drugEuropean Heart Journal
researchProduct

Oxidative stress and early organ damage in essential hypertension

2001

medicine.medical_specialtybusiness.industryDNA damagemedicine.diseaseEssential hypertensionLeft ventricular hypertrophymedicine.disease_causechemistry.chemical_compoundEndocrinologychemistryInternal medicineInternal MedicinemedicineGlutathione disulfideDeoxyguanosineMicroalbuminuriabusinessOxidative stressWhole bloodAmerican Journal of Hypertension
researchProduct

Insulin resistance and familial dyslipidaemias

1999

medicine.medical_specialtybusiness.industryEndocrinology Diabetes and MetabolismHypercholesterolemiaHyperlipidemia Familial CombinedHyperlipidemiasLipid Metabolismmedicine.diseaseHyperlipoproteinemia Type IVEndocrinologyInsulin resistanceEndocrinologyInternal medicineInternal MedicinemedicineHumansInsulin ResistancebusinessDiabetes, Obesity and Metabolism
researchProduct

Keyhole Suboccipital Endoscopic-Assisted Microsurgical Approach for Management of Pineal Region Tumors

2019

medicine.medical_specialtybusiness.industryEndoscopic assistedMedicineRadiologybusinessKeyholePineal region tumors29th Annual Meeting North American Skull Base Society
researchProduct

Lomitapide treatment highly affects lipoprotein profile and HDL functionality in patients with familial hypercholesterolemia

2015

medicine.medical_specialtybusiness.industryFamilial hypercholesterolemiamedicine.diseaseLomitapidechemistry.chemical_compoundEndocrinologychemistryInternal medicinemedicineIn patientHdl functionalityCardiology and Cardiovascular MedicinebusinessLipoproteinAtherosclerosis
researchProduct