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Taste of Fat and Obesity: Different Hypotheses and Our Point of View
2022
Obesity results from a temporary or prolonged positive energy balance due to an alteration in the homeostatic feedback of energy balance. Food, with its discriminative and hedonic qualities, is a key element of reward-based energy intake. An alteration in the brain reward system for highly palatable energy-rich foods, comprised of fat and carbohydrates, could be one of the main factors involved in the development of obesity by increasing the attractiveness and consumption of fat-rich foods. This would induce, in turn, a decrease in the taste of fat. A better understanding of the altered reward system in obesity may open the door to a new era for the diagnosis, management and treatment of th…
Effect of Non-Surgical Periodontal Treatment on Oxidative Stress Markers in Leukocytes and Their Interaction with the Endothelium in Obese Subjects w…
2020
Aim: The primary objective of this pilot study was to evaluate the effect of non-surgical periodontal treatment. The secondary aim was to evaluate the effect of dietary therapy on both parameters of oxidative stress in leukocytes and leukocyte-endothelial cell interactions in an obese population. Methods: This was a pilot study with a before-and-after design. Forty-nine obese subjects with periodontitis were randomized by means of the minimization method and assigned to one of two groups, one of which underwent dietary therapy while the other did not. All the subjects underwent non-surgical periodontal treatment. We determined periodontal, inflammatory and oxidative stress parameters&mdash
The corticotrophin-releasing factor/urocortin system regulates white fat browning in mice through paracrine mechanisms.
2015
Objectives:\ud The corticotrophin-releasing factor (CRF)/urocortin system is expressed in the adipose tissue of mammals, but its functional role in this tissue remains unknown.\ud \ud Methods:\ud Pharmacological manipulation of the activity of CRF receptors, CRF1 and CRF2, was performed in 3T3L1 white pre-adipocytes and T37i brown pre-adipocytes during in vitro differentiation. The expression of genes of the CRF/urocortin system and of markers of white and brown adipocytes was evaluated along with mitochondrial biogenesis and cellular oxygen consumption. Metabolic evaluation of corticosterone-deficient or supplemented Crhr1-null (Crhr1−/−) mice and their wild-type controls was performed alo…
High-Fat Diet Induces Pre-Diabetes and Distinct Sex-Specific Metabolic Alterations in Negr1-Deficient Mice
2021
In the large GWAS studies, NEGR1 gene has been one of the most significant gene loci for body mass phenotype. The purpose of the current study was to clarify the role of NEGR1 in the maintenance of systemic metabolism, including glucose homeostasis, by using both male and female Negr1−/− mice receiving a standard or high fat diet (HFD). We found that 6 weeks of HFD leads to higher levels of blood glucose in Negr1−/− mice. In the glucose tolerance test, HFD induced phenotype difference only in male mice
Fighting the Consequences of the COVID-19 Pandemic: Mindfulness, Exercise, and Nutrition Practices to Reduce Eating Disorders and Promote Sustainabil…
2023
Over the past two years, the world’s population has been tested by the COVID-19 health emergency. This has changed population habits worldwide by encouraging a sedentary lifestyle and overnutrition. Isolation and reduction of social life, for most of the population, was mandatory but it quickly became a new lifestyle. Nowadays, we are encountering the consequences with an increase in nutritional associated disorders and conditions that cause illnesses in the general population. These disorders include diet excesses that lead to obesity and diet deficiencies and malnutrition which could rapidly lead to death. These eating disorders are very complex to manage because they become mental disord…
Le petit appétit du grand âge
2018
National audience
Vieillissement, adaptation alimentaire au grand âge et petit appétit : le petit mangeur âgé
2018
Atteindre un âge canonique de 100 ans avec toutes les fonctions cognitives et physiques de l'âge adulte est le souhait de chacun. Pour autant, avec le vieillissement, l'héritage génétique, les conditions de vie durant la vie adulte et certains accidents de la vie peuvent faire basculer des personnes âgées plus rapidement que d'autres vers la dépendance, la dénutrition, la fragilité. Simone de Beauvoir écrivait « la sénescence n'est pas une pente que chacun descend à la même vitesse. C'est une volée de marches irrégulières que certains dégringolent plus vite que d'autres ». Le vieillissement a ses surprises et pour un même âge de 90 ans, alors que certains peuvent rivaliser avec les plus jeu…
A person-oriented approach to maternal homework involvement during the transition to lower secondary school
2022
This study examined patterns of mothers' homework involvement (n = 680 in Grade 6 and 665 in Grade 7) and changes in them during 12-year-old Finnish adolescents' (n = 848; 391 boys) transition to lower secondary school. Moreover, the extent to which adolescents' motivational behavior and prior academic achievement predicted these patterns was examined. The latent transition analyses identified four relatively stable latent patterns of maternal homework involvement in Grades 6 and 7: averagely involved, psychologically controlling and intrusive, noninvolved, and intrusive monitoring and helping. The higher task avoidance and the poorer achievement adolescents showed, the more likely their mo…
Fostering the relationship between home and school : a case study of a senior secondary school in the Gambia
2011
The study examines the extent to which the relationship between home and school affects students’ academic achievements. A senior secondary school in The Gambia was chosen for this study. The focus of the research was to identify and describe intentionally designed programs and practices that foster the involvement of home in school activities and its important outcomes for the stakeholders (home and school). A qualitative method using semi-structured interviews was used to collect the data from the school principal, four English language teachers and ten parents in order to explore the nature and the degree of support they provide for students. The data was analyzed by the researcher using…
The interplay between maternal homework involvement, task-avoidance, and achievement among adolescents.
2021
This study examined three aspects of maternal homework involvement (i.e., the quantity, quality, and source of initiative) and their direct and indirect associations with adolescents’ task-avoidant behavior in homework situations and academic achievement. The sample consisted of Finnish mothers and their adolescents who were transitioning from primary to lower secondary school. Mothers rated the quantity of their homework involvement (i.e., monitoring and help), quality of their homework involvement (i.e., autonomy support and psychological control), and source of initiative (i.e., mother- vs. adolescent-initiated monitoring and help) at the beginning of Grade 6. They also reported on adole…