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The Association of Schools of Public Health in the European Region Statement on the Erosion of Public Health Systems
2021
Lièvre et lapin à Regourdou (Montignac-sur-Vézère, Dordogne, France) : études paléontologique et taphonomique de deux accumulations osseuses d’origin…
2015
Since the end of the nineteenth century, a great deal of work studyingsubsistence patterns of prehistoric societies in Western Europe has been done. During the Middle Paleolithic, humanswere interested in small game, particularly the Leporidae, taxa that were abundant in their territories. However,distinguishing the exact nature of their origin in an archaeological site is not an easy task, given that numerous agentscould be responsible for their accumulation (i.e., natural mortality, acquisition by humans and/or other terrestrialcarnivores, or even nocturnal or diurnal raptors). In this contribution, we put forth a new taphonomic and paleontologicalstudy of the leporids of Regourdou, a Mou…
Focal Cortical Lesions Induce Bidirectional Changes in the Excitability of Fast Spiking and Non Fast Spiking Cortical Interneurons
2014
A physiological brain function requires neuronal networks to operate within a well-defined range of activity. Indeed, alterations in neuronal excitability have been associated with several pathological conditions, ranging from epilepsy to neuropsychiatric disorders. Changes in inhibitory transmission are known to play a key role in the development of hyperexcitability. However it is largely unknown whether specific interneuronal subpopulations contribute differentially to such pathological condition. In the present study we investigated functional alterations of inhibitory interneurons embedded in a hyperexcitable cortical circuit at the border of chronically induced focal lesions in mouse …
Conferència: "La dedicació de Sanchis Guarner a la filologia"
2011
Conferència "La dedicació de Sanchis Guarner a la filologia", han intervingut els membres de l'IEC Joan Veny i Brauli Montoya, i també Vicent Simbor, de la Universitat de València, moderats per Antoni Ferrando, membre de l'IEC i professor de la Universitat de València.
Conferència "La figura humana de Sanchis Guarner en al seu temps"
2011
Conferència "La dedicació de Sanchis Guarner a la filologia". Homenatge al filòleg Manuel Sanchis Guarner.
Existence de points fixes enlacés à une orbite périodique d'un homéomorphisme du plan
1992
Let f be an orientation-preserving homeomorphism of the plane such that f-Id is contracting. Under these hypotheses, we establish the existence, for every periodic orbit, of a fixed point which has nonzero linking number with this periodic orbit.
Synaptic scaling generically stabilizes circuit connectivity
2011
Neural systems regulate synaptic plasticity avoiding overly strong growth or shrinkage of the connections, thereby keeping the circuit architecture operational. Accordingly, several experimental studies have shown that synaptic weights increase only in direct relation to their current value, resulting in reduced growth for stronger synapses [1]. It is, however, difficult to extract from these studies unequivocal evidence about the underlying biophysical mechanisms that control weight growth. The theoretical neurosciences have addressed this problem by exploring mechanisms for synaptic weight change that contain limiting factors to regulate growth [2]. The effectiveness of these mechanisms i…
Structural changes induced by daily music listening in the recovering brain after middle cerebral artery stroke: a voxel-based morphometry study
2014
[Abstract.] Music is a highly complex and versatile stimulus for the brain that engages many temporal, frontal, parietal, cerebellar, and subcortical areas involved in auditory, cognitive, emotional, and motor processing. Regular musical activities have been shown to effectively enhance the structure and function of many brain areas, making music a potential tool also in neuro- logical rehabilitation. In our previous randomized controlled study, we found that listening to music on a daily basis can improve cognitive recovery and improve mood after an acute mid- dle cerebral artery stroke. Extending this study, a voxel-based morphometry (VBM) analysis utilizing cost function masking was perf…
PINK1: a critical protein kinase in the molecular mechanisms involved in Cancer and Parkinson's disease
2012
El cáncer y la enfermedad de Parkinson (PD) son dos enfermedades en las que el mecanismo pato- fisiológico final no está completamente definido. Datos epidemiológicos indican que los pacientes con PD poseen bajo riesgo de cáncer, con la excepción de melanoma maligno y cánceres de piel, tiroides y mama, lo que sugiere una conexión funcional entre PD y cáncer. Apoyando esta conexión, la desregulación de la homeostasis mitocondrial es una característica importante en la patogénesis de ambas enfermedades. Recientemente, varios genes asociados a PD, tales como Parkin, LRRK2, DJ-1, y PINK1, han sido propuestos como moduladores de procesos cancerígenos. Mutaciones en el gen de PINK1 están asociada…
Participación ciudadana e inmigración: consideraciones políticas y jurídicas
2019
RESUMEN. La participación ciudadana es el elemento clave en la labor de integración de las personas migrantes. La perspectiva política y la jurídica de esta cuestión se estudian en el presente trabajo para concluir que el derecho humano a la participación ciudadana es la base sobre la que edificar las democracias del siglo XXI, que no podrán mantener la estructura de ciudadanías de dos velocidades que forman su sociedad. La integración ha de ser lo más completa posible, y ello implica un mayor reconocimiento de derechos a los migrantes, fundamentalmente en el escenario de la participación ciudadana.