Search results for "hormone"
showing 10 items of 2056 documents
Glucagon-like peptidi-2 action and GLP-2 receptor expression in stomach of mice fed a high fat diet or fasted.
2011
Are gut hormones responsible for the decrease of appetitive behaviour for sweet and fatty foods after gastric bypass surgery?
2013
WOS: 000321389200211; International audience; Introduction: Gastric bypass surgery (RYGB) decreases preference for sweet and fatty foods, but the underlying mechanism is not known. This study aimed to investigate the role of the exaggerated satiety gut hormone release on appetitive reward of sweet and fatty taste after RYGB. Method: 13 patients that have undergone previous RYGB surgery (>6 months) and 13 normal weight controls participated in a double-blind placebo-controlled trial comparing the effect of subcutaneous injections of somatostatin analogue (octreotide) which blocks satiety gut hormone responses, and saline (control) on the appetitive reward value of sweet-fat candies. Appetiti…
Sex steroid hormone receptors, their ligands, and nuclear and non-nuclear pathways
2015
The ability of a cell to respond to a particular hormone depends on the presence of specific receptors for those hormones. Once the hormone has bound to its receptor, and following structural and biochemical modifications to the receptor, it separates from cytoplasmic chaperone proteins, thereby exposing the nuclear localization sequences that result in the activation of the receptor and initiation of the biological actions of the hormone on the target cell. In addition, recent work has demonstrated new pathways of steroid signaling through orphan and cell surface receptors that contribute to more rapid, “non-nuclear” or non-transcriptional effects of steroid hormones, often involving G-pro…
LH administration as a potential strategy for ovarian protection and female fertility preservation against highly gonadotoxic chemotherapy
2022
Els ovaris contenen una reserva de fol·licles no renovable, que produeixen un únic ovòcit fecundable a cada cicle menstrual al llarg de l'etapa reproductiva femenina (15-49 anys), però que disminueix progressivament amb l'edat. Per tant, els factors que afecten negativament la dotació de fol·licles provocaran una reducció significativa de la vida reproductiva en la dona. Les teràpies oncològiques basades en l'administració de quimioteràpia alquilant s'utilitzen habitualment per a tractar els càncers ginecològics en pacients joves, però amb freqüència acceleren l'esgotament de la reserva fol·licular i l'aparició de la menopausa. Els efectes secundaris de la quimioteràpia sobre la fertilitat,…
Plausible Role of Estrogens in Pathogenesis, Progression and Therapy of Lung Cancer
2021
Malignant neoplasms are among the most common diseases and are responsible for the majority of deaths in the developed world. In contrast to men, available data show a clear upward trend in the incidence of lung cancer in women, making it almost as prevalent as breast cancer. Women might be more susceptible to the carcinogenic effect of tobacco smoke than men. Furthermore, available data indicate a much more frequent mutation of the tumor suppressor gene-p53 in non-small cell lung cancer (NSCLC) female patients compared to males. Another important factor, however, might lie in the female sex hormones, whose mitogenic or carcinogenic effect is well known. Epidemiologic data show a correlatio…
Maternally‐transferred thyroid hormones and life‐history variation in birds
2022
1. In vertebrates, thyroid hormones (THs) play an important role in the regulation of growth, development, metabolism, photoperiodic responses and migration. Maternally transferred THs are important for normal early-phase embryonic development when embryos are not able to produce endogenous THs. Previous studies have shown that variation in maternal THs within the physiological range can influence offspring phenotype. 2. Given the essential functions of maternal THs in development and metabolism, THs may be a mediator of life-history variation across species. 3. We tested the hypothesis that differences in life histories are associated with differences in maternal TH transfer across species…
Obtaining and research of callus mass of Gentiana lutea L roots
2015
The results of introduction to the culture in vitro Gentiana lutea L. are provided. The influence of phytohormones on growth processes of plant cells is researched, the optimal conditions for cultivation of Gentiana lutea L. are defined and chosen. Biomass extract is obtained and is researched on the presence in it the biologically active substances and antimicrobial activity.
Motherhood‐induced gene expression in the mouse medial amygdala: Changes induced by pregnancy and lactation but not by pup stimuli
2021
During lactation, adult female mice display aggressive responses toward male intrud-ers, triggered by male- derived chemosensory signals. This aggressive behavior is not shown by pup- sensitized virgin females sharing pup care with dams. The genetic mechanisms underlying the switch from attraction to aggression are unknown. In this work, we investigate the differential gene expression in lactating females ex-pressing maternal aggression compared to pup- sensitized virgin females in the me-dial amygdala (Me), a key neural structure integrating chemosensory and hormonal information. The results showed 197 genes upregulated in dams, including genes encoding hormones such as prolactin, growth h…
Growth-associated variation in body size, hormonal status, physical performance characteristics and perceptual-motor skills in Finnish young soccer p…
2013
Acute hormonal and muscular responses and recovery : chronic adaptations to single session combined strength and endurance training with regard to or…
2012
Combining both strength (S) and endurance (E) exercise loadings into a single training session can be considered to be of interest e.g. for time management purposes. However, the first loading in a combined session tends to produce notable acute fatigue responses, which can lead to the second loading being performed in a compromised state. Research on fatigue and recovery from a combined session with different loading orders is currently scarce, with even less attention given to the acute responses. Thus, this study investigated the long-term adaptations in the acute responses of a combined strength and endurance loading and whether or not there is an order effect. A total of 29 male subjec…