Search results for "hospitalization"

showing 10 items of 463 documents

Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-l…

2009

Udgivelsesdato: 2009-Jun-20 BACKGROUND: Rosiglitazone is an insulin sensitiser used in combination with metformin, a sulfonylurea, or both, for lowering blood glucose in people with type 2 diabetes. We assessed cardiovascular outcomes after addition of rosiglitazone to either metformin or sulfonylurea compared with the combination of the two over 5-7 years of follow-up. We also assessed comparative safety. METHODS: In a multicentre, open-label trial, 4447 patients with type 2 diabetes on metformin or sulfonylurea monotherapy with mean haemoglobin A(1c) (HbA(1c)) of 7.9% were randomly assigned to addition of rosiglitazone (n=2220) or to a combination of metformin and sulfonylurea (active con…

MaleMyocardial InfarctionAdministration OralType 2 diabeteslaw.inventionFractures BoneRandomized controlled triallawNeoplasmsClinical endpointMyocardial infarctionrosiglitazone; cardiovascular outcomesProspective StudiesDiureticsGeneral MedicineMiddle AgedMetforminMetforminHospitalizationStrokeDrug Therapy CombinationFemaleRosiglitazonemedicine.drugmedicine.medical_specialtyRosiglitazoneSex FactorsInternal medicineDiabetes mellitusmedicineHumansHypoglycemic AgentsAngina UnstableDiabetes Rosiglitazone Cardiovascular RiskHemoglobin A GlycosylatedGlycated HemoglobinHeart FailureIntention-to-treat analysisbusiness.industryBody WeightCholesterol HDLCholesterol LDLtype 2 diabetes; rosiglitazonemedicine.diseaseDrug UtilizationSurgerySulfonylurea CompoundsDiabetes Mellitus Type 2ThiazolidinedionesHydroxymethylglutaryl-CoA Reductase InhibitorsbusinessLancet (London, England)
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Analysis of risk and prognostic factors in a population of pediatric patients hospitalized for acute malnutrition at the Chiulo hospital, Angola

2021

Abstract Background Malnutrition is a multifactorial pathology in which genetic, epigenetic, cultural, environmental, socio-economic factors interact with each other. The impact that this disease has on the health of children worldwide is dramatic. Severe acute malnutrition in particular is a disease affecting nearly 20 million preschool children worldwide, most of them in Africa and South East Asia. Objectives This work aims to investigate potential prognostic factors in the clinical evolution of acute malnutrition and potential risk factors for the development of the disease. Methods Our study was carried out at the “Hospital da Missão Catolica do Chiulo”, in Angola, where the NGO Doctors…

MaleNutrition EducationPopulationSevere Acute MalnutritionBreastfeedingBreastfeedingDiseasePrognostic factorsChild Nutrition DisordersPediatricsRJ1-570Environmental healthHumansMedicineeducationWastingPrognostic factorFamily Characteristicseducation.field_of_studyFamily unitSub-Saharan Africabusiness.industryWasting.ResearchBody WeightInfantPrognosismedicine.diseaseBody HeightWastingHospitalizationMalnutritionAngolaRisk factorsFood SecuritySevere acute malnutritionChild PreschoolFemaleRisk factormedicine.symptombusinessItalian Journal of Pediatrics
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Point of view of the Italians pediatric scientific societies about the pediatric care during the COVID-19 lockdown: What has changed and future prosp…

2020

Abstract Background The coronavirus disease 2019 (COVID-19) is currently rare in children and they seem to have a milder disease course and better prognosis than adults. However, SARS-Cov-2 pandemic has indirectly caused problems in pediatric medical assistance. In view of this we wanted to draw a picture of what happened during health emergency and analyze future prospects for restarting. Methods We involved the Italian pediatric scientific societies institutionally collected in the Italian Federation of Associations and Scientific Societies of the Pediatric Area (FIARPED); We sent a questionnaire to all scientific societies about the pediatric care activity during the COVID-19 emergency a…

MaleOutcome AssessmentPediatricsPatient Care PlanningSurveys and QuestionnairesPandemicOutcome Assessment Health CareAmbulatory CareMedicineViralChildChildrenSocieties MedicalPediatricEmergency Servicelcsh:RJ1-570children; COVID-19; pediatric assistance; telemedicineSettore MED/38TelemedicineHospitalizationOutpatient visitsItalySettore MED/38 - PEDIATRIA GENERALE E SPECIALISTICAQuarantineContinuity of careFemalePediatric careCoronavirus InfectionsEmergency Service HospitalHumanAdultmedicine.medical_specialtyTelemedicineCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pneumonia ViralDisease courseHospitalMedicalHumansPandemicsInfection ControlPediatric assistancePandemicbusiness.industryCoronavirus InfectionCOVID-19lcsh:PediatricsPneumoniaHealth CareFamily medicineChildren; COVID-19; Pediatric assistance; Telemedicine; Adult; Ambulatory Care; Child; Coronavirus Infections; Delivery of Health Care; Emergency Service Hospital; Female; Hospitalization; Humans; Infection Control; Italy; Male; Outcome Assessment Health Care; Pandemics; Patient Care Planning; Pediatrics; Pneumonia Viral; Quarantine; Societies Medical; Telemedicine; Surveys and QuestionnairesbusinessSocietiesDelivery of Health Care
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Utility of Urine Neutrophil Gelatinase-Associated Lipocalin for Worsening Renal Function during Hospitalization for Acute Heart Failure: Primary Find…

2019

ABSTRACT Background: Worsening renal function (WRF) during acute heart failure (AHF) occurs frequently and has been associated with adverse outcomes, though this association has been questioned. WRF is now evaluated by function and injury. We evaluated whether urine neutrophil gelatinase-associated lipocalin (uNGAL) is superior to creatinine for prediction and prognosis of WRF in patients with AHF. Methods and Results: We performed a multicenter, international, prospective cohort of patients with AHF requiring IV diuretics. The primary outcome was whether uNGAL predicted development of WRF, defined as a sustained increase in creatinine of 0.5 mg/dL or ≥50% above first value or initiation of…

MalePROGNOSISInternationalitymedicine.medical_treatmentUrine030204 cardiovascular system & hematologyKidneyKidney Function TestsGastroenterologyTHERAPYCohort Studieschemistry.chemical_compound0302 clinical medicine030212 general & internal medicineProspective StudiesProspective cohort studyDAMAGERISKAged 80 and overAcute kidney injuryIMPAIRMENTAcute Kidney InjuryMiddle Aged3. Good healthHospitalizationbiomarkerAcute heart failure; biomarker; worsening renal functionFemaleCardiology and Cardiovascular MedicineGlomerular Filtration Ratemedicine.medical_specialtyRenal functionDIAGNOSIS03 medical and health sciencesLipocalin-2Internal medicineSTRATIFICATIONmedicineMANAGEMENTHumansRenal replacement therapyAdverse effectAgedHeart FailureCreatininebusiness.industryMORTALITYAcute heart failuremedicine.diseasechemistryHeart failureworsening renal functionbusinessBiomarkersJournal of cardiac failure
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Is there a right place to pace the right ventricle? Evaluation of apical and septal positions in a pacemaker population: Study protocol for a prospec…

2014

Abstract Introduction The main objective of research in pacemaker therapy has been to provide the best physiologic way to pace the heart. Despite the good results provided by right ventricular pacing minimization and by biventricular pacing in specific subsets of heart failure patients, these options present many limitations for standard pacemaker recipients. In these patients, pacing the right ventricle at alternative sites could result in a lower degree of left intraventricular dyssynchrony. Despite the lack of strong evidence and the difficulty in placing and accurately classifying the final lead position, pacing at alternative right ventricular sites seems to have become a standard proc…

MalePacemaker Artificialmedicine.medical_specialtyHeart Ventriclesmedicine.medical_treatmentPopulationCardiac resynchronization therapySTUDY DESIGNSeverity of Illness IndexInternal medicinePACEMAKERmedicineHumansSingle-Blind MethodPharmacology (medical)Prospective StudieseducationVentricular dyssynchronyHeart Failureeducation.field_of_studyEjection fractionDYSSYNCHRONYbusiness.industryGeneral Medicinemedicine.diseaseImplantable cardioverter-defibrillatorHospitalizationmedicine.anatomical_structureEchocardiographyResearch DesignVentriclePACEMAKER; STUDY DESIGN; DYSSYNCHRONYHeart failureQuality of LifeCardiologyEnd-diastolic volumeFemalebusinessContemporary Clinical Trials
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Surveillance Data for Eight Consecutive Influenza Seasons in Sicily, Italy

2019

Influenza A and B outbreaks occur each year with different activity and molecular patterns. To date, knowledge of seasonal epidemiology remains a prerequisite not only to put in place the most effective immunization strategy against influenza but also to identify population groups at higher risk of developing serious complications. A retrospective analysis of influenza surveillance data from 2010 to 2018 aimed to explore the epidemiology of influenza in Sicily, at the primary care and hospital level. Overall, 6,740 patients with acute respiratory infection were tested, of which 3,032 (45.0%) were positive for influenza. The relative proportion of type A and B viruses markedly varied across …

MalePediatricsCommunityDiseaseSettore MED/42 - Igiene Generale E ApplicataSeverity of Illness IndexDisease Outbreakslaw.inventionRisk FactorslawEpidemiologyChildRespiratory Tract InfectionsSicilyeducation.field_of_studyVaccinationRespiratory infectionArticlesMiddle AgedIntensive care unitHospitalizationIntensive Care UnitsInfectious DiseasesMolecular surveillanceInfluenza A virusChild PreschoolEpidemiological MonitoringFemaleSeasonsAdultmedicine.medical_specialtyAdolescentPopulationYoung AdultVirologyInfluenza HumanmedicineHumanseducationAgedRetrospective Studiesbusiness.industryInfantOutbreakmedicine.diseaseObesityInfluenzaInfluenza B virusImmunizationParasitologyRisk factorbusinessThe American Journal of Tropical Medicine and Hygiene
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Rising Stroke Incidence in Young Adults: More Epidemiological Evidence, More Questions to Be Answered

2016

Studies have reported increasing incidence of ischemic stroke in adults younger than 50 to 55 years. Information on temporal trends of other stroke subtypes and transient ischemic attack (TIA) is sparse. The aim of this study was to investigate temporal trends of the incidence of hospitalizations for TIA and stroke including sex- and subtype-specific trends in young adults aged 15 to 30 years.From the Danish National Patient Register, we identified all cases of first-ever stroke and TIA (age 15-30 years) in Denmark, who were hospitalized during the study period of 1994 to 2012. Incidence rates and estimated annual percentage changes (EAPCs) were estimated by using Poisson regression. During…

MalePediatricsDenmarkPrevalencepopulation030204 cardiovascular system & hematologyburden0302 clinical medicineRisk FactorsCardiovascular DiseaseEpidemiologyMedicinePoisson DistributionRegistriesYoung adultStrokeComputingMilieux_MISCELLANEOUSOriginal ResearchIncidence (epidemiology)[ SDV.MHEP.CSC ] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemstroke3. Good healthEditorialIschemic Attack TransientRegression AnalysisFemaleepidemiologyFranceCardiology and Cardiovascular MedicineStroke incidencehospitalizationAdulttrendsmedicine.medical_specialtyacute ischemic strokeAdolescentprevalencenationwide inpatient sample03 medical and health sciencesYoung Adult[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemHumanscardiovascular diseasesSex DistributionCerebral HemorrhageIschemic Strokebusiness.industryyoungEditorialsSubarachnoid Hemorrhagemedicine.diseasetransient ischemic attackincidenceCerebrovascular Disease/Strokebusiness030217 neurology & neurosurgery
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Personal and Environmental Risk Factors at Birth and Hospital Admission: Direct and Vitamin D-Mediated Effects on Bronchiolitis Hospitalization in It…

2021

Seasonal variations in UV-B radiation may influence vitamin D status, and this, in turn, may influence the risk of bronchiolitis hospitalization. The aim of this study was using a causal inference approach to investigate, simultaneously, the interrelationships between personal and environmental risk factors at birth/hospital admission (RFBH), serum vitamin D levels and bronchiolitis hospitalization. A total of 63 children (&lt

MalePediatricsHealth Toxicology and Mutagenesislcsh:Medicinevitamin Dchemistry.chemical_compoundSettore MED/38 - Pediatria Generale E Specialistica0302 clinical medicinePregnancyRisk Factors030212 general & internal medicineChildseasonalityGestational ageVitaminsHospitalsHospitalizationItalyChild PreschoolHospital admissionBronchiolitisPremature BirthFemaleSeasonsVitaminmedicine.medical_specialtyUltraviolet RaysBirth weightGestational AgeEnvironmentLower riskArticle03 medical and health sciencesEnvironmental risk030225 pediatricsmedicineVitamin D and neurologyHumansmediation analysisbusiness.industrylcsh:RPublic Health Environmental and Occupational HealthInfant NewbornInfantmediation analysimedicine.diseasebronchiolitis hospitalizationchemistryBronchiolitisbusinessInternational Journal of Environmental Research and Public Health
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e-Health-based management of patients receiving oral anticoagulation therapy: results from the observational thrombEVAL study

2017

Essentials e-Health based health care by an expert centre may advance management of oral anticoagulation. Outcome of patients was compared between an e-health based coagulation service and regular care. Patients in the coagulation service cohort experienced a significantly better clinical outcome. Lower risk for adverse events was related to anticoagulation-specific and non-specific outcome. SummaryBackground Management of oral anticoagulation (OAC) therapy is essential to minimize adverse events in patients receiving vitamin K-antagonists (VKAs). Data on the effect of e-health-based anticoagulation management systems on the clinical outcome of OAC patients are limited. Objectives To compar…

MalePediatricsVitamin KAdministration OralComorbidity030204 cardiovascular system & hematologyRate ratioSERVICE0302 clinical medicineRisk FactorsGermanyUSUAL MEDICAL-CAREClinical endpointProspective Studies030212 general & internal medicineAged 80 and overOUTCOMESHazard ratioDABIGATRANHematologyMiddle AgedHospitalizationTreatment OutcomeCohortdelivery of healthcareFemaleepidemiologyPatient SafetytelemedicineCohort studymedicine.drugmedicine.medical_specialtyanticoagulantsHemorrhageLower riskpatient outcome assessmentWARFARIN03 medical and health sciencesThromboembolismmedicineNONVALVULAR ATRIAL-FIBRILLATIONHumansQUALITYInternational Normalized RatioAdverse effectBlood CoagulationMETAANALYSISAgedProportional Hazards ModelsRivaroxabanbusiness.industrySTROKE PREVENTIONRIVAROXABANbusinessFollow-Up Studies
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Paediatric intensive care admissions for respiratory syncytial virus bronchiolitis in France: results of a retrospective survey and evaluation of the…

2012

SUMMARYThe purpose of this study was to describe the characteristics of patients with bronchiolitis admitted to a paediatric intensive care unit (PICU), and to evaluate a national registry of hospitalizations (Programme de Médicalisation des Systèmes d'Information; PMSI) as a potential source of epidemiological data. Of the 49 French PICUs invited to take part in a retrospective survey of children aged <2 years who were hospitalized during the 2005–2006 epidemic season, 24 agreed to participate. Overall, 467 children were enrolled: 75% were aged <2 months, 76% had positive respiratory syncytial virus (RSV) tests, 34·9% required non-invasive ventilation, 36·6% were mechanically ventila…

MalePediatricsmedicine.medical_specialtyDatabases FactualEpidemiologymedicine.medical_treatment[ SDV.MHEP.PED ] Life Sciences [q-bio]/Human health and pathology/PediatricsRespiratory Syncytial Virus InfectionsIntensive Care Units Pediatric03 medical and health sciencesDatabases0302 clinical medicine030225 pediatricsEpidemiologymedicineBronchiolitis ViralHumans030212 general & internal medicineViralFactualRetrospective StudiesMechanical ventilationPediatric[SDV.MHEP.PED]Life Sciences [q-bio]/Human health and pathology/Pediatricsbusiness.industryMortality rateRespirationRespiratory diseaseInfant NewbornInfantReproducibility of ResultsRetrospective cohort studymedicine.diseaseNewbornRespiration Artificial3. Good healthRespiratory Syncytial VirusesHospitalizationIntensive Care UnitsInfectious DiseasesBronchopulmonary dysplasiaBronchiolitisArtificialBreathingBronchiolitisFemaleFrancebusiness
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