6533b831fe1ef96bd1299b4b

RESEARCH PRODUCT

Paediatric intensive care admissions for respiratory syncytial virus bronchiolitis in France: results of a retrospective survey and evaluation of the validity of a medical information system programme

Anne-laure SoillyJean-bernard GouyonMarianne GrimaldiO. DesplanchesCyril Ferdynus

subject

MalePediatricsmedicine.medical_specialtyDatabases FactualEpidemiologymedicine.medical_treatment[ SDV.MHEP.PED ] Life Sciences [q-bio]/Human health and pathology/PediatricsRespiratory Syncytial Virus InfectionsIntensive Care Units Pediatric03 medical and health sciencesDatabases0302 clinical medicine030225 pediatricsEpidemiologymedicineBronchiolitis ViralHumans030212 general & internal medicineViralFactualRetrospective StudiesMechanical ventilationPediatric[SDV.MHEP.PED]Life Sciences [q-bio]/Human health and pathology/Pediatricsbusiness.industryMortality rateRespirationRespiratory diseaseInfant NewbornInfantReproducibility of ResultsRetrospective cohort studymedicine.diseaseNewbornRespiration Artificial3. Good healthRespiratory Syncytial VirusesHospitalizationIntensive Care UnitsInfectious DiseasesBronchopulmonary dysplasiaBronchiolitisArtificialBreathingBronchiolitisFemaleFrancebusiness

description

SUMMARYThe purpose of this study was to describe the characteristics of patients with bronchiolitis admitted to a paediatric intensive care unit (PICU), and to evaluate a national registry of hospitalizations (Programme de Médicalisation des Systèmes d'Information; PMSI) as a potential source of epidemiological data. Of the 49 French PICUs invited to take part in a retrospective survey of children aged <2 years who were hospitalized during the 2005–2006 epidemic season, 24 agreed to participate. Overall, 467 children were enrolled: 75% were aged <2 months, 76% had positive respiratory syncytial virus (RSV) tests, 34·9% required non-invasive ventilation, 36·6% were mechanically ventilated, and six infants died. The main neonatal characteristics were: prematurity (31·9%), respiratory disease (16·5%), congenital heart disease (6·4%), receiving mechanical ventilation (11·6%), and bronchopulmonary dysplasia at day 28 (3·8%). For bronchiolitis episode, the kappa coefficient between the survey and PMSI data was good only for mechanical ventilation (0·63) and the death rate (0·86).

http://hal.univ-reunion.fr/hal-01194213