Search results for "hsc"
showing 10 items of 123 documents
Nuclear Translocation of Papillomavirus Minor Capsid Protein L2 Requires Hsc70
2004
ABSTRACT Minor capsid protein L2 of papillomaviruses plays an essential role in virus assembly by recruiting viral components to PML bodies, the proposed sites of virus morphogenesis. We demonstrate here that the function of L2 in virus assembly requires the chaperone Hsc70. Hsc70 was found dispersed in naturally infected keratinocytes and cultured cells. A dramatic relocation of Hsc70 from the cytoplasm to PML bodies was induced in these cells by L2 expression. Hsc70-L2 complex formation was confirmed by coimmunoprecipitation. The complex was modulated by the cochaperones Hip and Bag-1, which stabilize and destabilize Hsc70-substrate complexes, respectively. Cytoplasmic depletion of Hsc70 …
GLOBAL DELAY TIME FOR GENERAL DISTRIBUTED NETWORKS WITH APPLICATIONS TO TIMING ANALYSIS OF DIGITAL MOS INTEGRATED CIRCUITS
1989
We consider here a general nerwork composed by n‐distributed parameters lines (with telegraph‐equations models) and m‐capacitors, all connected by a resistive multiport. An asymptotic stability property drives us to define and evaluate a global parameter (“λ‐delay time”) which describes the speed of signals propagation through the network. Because of its simplicity of calculation and its tightness, the given upper bound of the λ‐delay time is useful in timing analysis of MOS integrated chips.
Die landwirthschaftlich-chemische Versuchsstation am Polytechnikum zu Riga, Lief. 2
1877
Bericht über die Thätigkeit in den Jahren 1874/75 und 1875/76.
Finnish vocational education and training in comparison: Strengths and weaknesses
2014
International journal for research in vocational education and training 1 (2014) 2, S. 81-106
The Time Response of Glass Resistive Plate Chambers to Heavily Ionizing Particles
2007
The HARP system of resistive plate chambers (RPCs) was designed to perform particle identification by the measurement of the difference in the time-of-flight of different particles. In previous papers an apparent discrepancy was shown between the response of the RPCs to minimum ionizing pions and heavily ionizing protons. Using the kinematics of elastic scattering off a hydrogen target a controlled beam of low momentum recoil protons was directed onto the chambers. With this method the trajectory and momentum, and hence the time-of-flight of the protons can be precisely predicted without need for a measurement of momentum of the protons. It is demonstrated that the measurement of the time-o…
Sea urchin embryos as an in vivo model for the assessment of manganese toxicity: developmental and stress response effects.
2009
In the marine environment increasing concentrations of bio-available compounds often result from anthropogenic activities. Among metal ions, manganese represents a new emergent factor in environmental contamination. Here, we studied the effects of manganese on Paracentrotus lividus sea urchin embryos using biological and biochemical approaches for the analysis of impact on development, tissue accumulation and stress markers. Embryos were continuously exposed from fertilization to manganese at concentrations ranging from 1.0 to 61.6 mg l(-1), monitored for developmental abnormalities at 48 h after fertilization, and used for atomic spectrometric analysis at various times from 6 to 72 h. We f…
Quasi-digital conversion for resistive devices: application in GMR-based IC current sensors
2013
Resistive devices, including sensors, are used in a huge range of applications within different scenarios. When a complete system is considered, a quasi-digital output is often recommendable. If the conversion is operated at device level, some problems such as noise disturbs, insertion losses and so on, can be reduced. In this work, we describe a resistance-tofrequency (R-f) converter with a suggested application in low current monitoring by means of GiantMagnetoResistance (GMR) sensors. Specific devices have been designed and microfabricated. The system has been tested by means of discrete components with a PCB. The complete microsystem monolithic integration in a standard CMOS technology …
STRUCTURAL OPTIMIZATION OF INNOVATIVE RUDDER FOR HSC
2012
Currently, directional and stability control systems (rudders and flaps) of high speed craft (HSC) are made by steel box-shaped elements. This is mainly caused by the high hydrodynamic stresses applied on these elements due to the high cruising speed of HSC. In order to reduce the weight of these elements and to increase the resistance to external corrosive action, innovative manufacturing technologies and new materials are studied. In this paper, innovative hybrid steel-composite rudder are presented to use in high speed craft.
Metastable memristive lines for signal transmission and information processing applications
2016
Traditional studies of memristive devices have mainly focused on their applications in nonvolatile information storage and information processing. Here, we demonstrate that the third fundamental component of information technologies-the transfer of information-can also be employed with memristive devices. For this purpose, we introduce a metastable memristive circuit. Combining metastable memristive circuits into a line, one obtains an architecture capable of transferring a signal edge from one space location to another. We emphasize that the suggested metastable memristive lines employ only resistive circuit components. Moreover, their networks (for example, Y-connected lines) have an info…