Search results for "hypertrophy"

Effect of Prolonged Physical Training on the Development of Connective Tissues in Growing Mice

1975

A rapid progress has taken place in the field of connective tissue chemistry during recent years. The structure and metabolism of collagen, elastin, glycosaminoglycans and pro-. teoglycans of different connective tissues have been extensively investigated. One of the main observations has been that large differences exist between various connective tissues [12]. For example, four different forms of collagen have been identified. The collagens in bone, cartilage, skin and basement membrane have either different amino acid composition in the a-chains or contain one or two similar a-chains in the triple helix. The scope of the connective tissue research has been extended also to skeletal muscl…

Association between biomarkers of inflammation and left ventricular hypertrophy in moderate chronic kidney disease.

2007

Aims: Left ventricular hyper- trophy (LVH) is a predictor for cardiovascu- lar mortality, and it is considered to be a surro- gate marker of preclinical cardiovascular dis- ease. This study aimed at evaluating whether fetuin-A plasma levels are decreased in pa- tients with moderate chronic kidney disease (CKD) and their linkage to plasma concentra- tions of hs-C-reactive protein (CRP), cardio- trophyn-1 (CT-1), tumor necrosis factor- (TNF-), propeptide of collagen Type I (PIP) and to LVH. Material and methods: We enrolled 64 moderate CKD and 55 essential hypertensives (EH) with normal renal func- tion as controls. All the patients underwent an echocardiographic examination; plasma sam- ples…

Hypertrophic adaptations of lower limb muscles in response to three different resistance training regimens

2020

Introduction: The research tested the effects of training in three different load zones. The hypothesis is that this type of training can provide more complete hypertrophic gains compared to workouts performed in a specific, single load area. Materials and methods: 37 participants were divided into 4 groups (SE; S; E; C). The first group trained simultaneously with high loads and low repetitions and with low loads and high repetitions; the second group trained in the high load condition, the third with low loads and high repetitions brought to the point of fatigue and the last control group had not practiced any type of training. The participants performed the training program 3 times a wee…

Retraction: Alcohol consumption and hormonal alterations related to muscle hypertrophy: a review

2014

Detrimental effects of acute and chronic alcohol (ethanol) consumption on human physiology are well documented in the literature. These adversely influence neural, metabolic, cardiovascular, and thermoregulatory functions. However, the side effects of ethanol consumption on hormonal fluctuations and subsequent related skeletal muscle alterations have received less attention and as such are not entirely understood. The focus of this review is to identify the side effects of ethanol consumption on the major hormones related to muscle metabolism and clarify how the hormonal profiles are altered by such consumption.

Neuromuscular Adaptations after Blood Flow Restriction Training Combined with Nutritional Supplementation: A Preliminary Study

2019

Blood fl ow restriction training (BFRT) has been shown to be an eff ective alternative technique to conventional resistance training to increase skeletal muscle hypertrophy and strength. However, neuromuscular response to BFRT in combination with nutritional supplementation has rarely been studied. Th e purpose of this study was to investigate the eff ects of BFRT combined with creatine monohydrate (CrM) and/or hydroxymethyl butyrate (HMB) on skeletal muscle size and strength. Fift een healthy males were randomly divided into three groups: a) BFRT without supplementation (C-BFR); b) BFRT with CrM supplementation (0.3 g / kg-1) (CrM-BFR); and c) BFRT with CrM (0.3 g / kg-1) and HMB (3 g) sup…

Optical coherence tomography in congenital hypertrophy of the retinal pigment epithelium.

2014

Oxidant stress and endothelial activation in hypertensive patients with and without left ventricular hypertrophy

2006

Cerebrovascular involvement in fabry disease: current status of knowledge.

2014

Fabry disease (FD) is a rare and highly debilitating lysosomal storage disorder that results from a total lack of, or deficiency in, the enzyme α-galactosidase A (α-Gal A) because of mutations in the GLA gene.1 FD is inherited as an X-linked trait; many of the male patients develop a classic severe phenotype with early onset of symptoms, whereas heterozygous females exhibit phenotypes ranging from asymptomatic to major involvement of vital organs.2 Most families inherit private mutations; to date, >600 mutations have been identified and are listed in the online FD database (Fabry-database.org).3 The deficiency in α-Gal A causes the accumulation of globotriaosylceramide (GL-3; also abbreviat…

Sudden death in water: Diagnostic challenges

2016

Abstract The authors report a case of sudden death in a breath-holding diver and highlight the forensic diagnostic difficulties in opining the cause of sudden death in water. The autopsy showed increased thickness of the left ventricular wall with a distinct pattern of concentric hypertrophy, evident particularly in the subaortic interventricular septum. Histological examination revealed diffuse interstitial fibrosis and associated findings of multifocal myocyte disarray especially evident in the subaortic interventricular septum. The analysis and discussion of this case made it possible to attribute sudden death to a lethal arrhythmia following myocyte disarray and hypoxia caused by breath…

Usefulness of DNA quantification in diagnosis of hypertrophic cardiomyopathies

2006

Hypertrophic cardiomyopathies (HCM) are a frequent cause of sudden death in both young people and adults. Different cardiomyopathies can be distinguished according to the etiological agent and, although there are morphological differences too, alterations in the quantity of DNA in the cardiomyocytes may play an important role in their pathogenesis and evolution. To understand the characteristics and the behaviour of the DNA index in hypertrophic cardiomyopathies, we have studied thirty cases (10 primaries or essential, 10 hypertensives and 10 toxic) and compared the results with those obtained for 10 macroscopically normal hearts. The results showed that the different cardiomyopathies were …