Search results for "iNOS"

Inhibition of FcεRI-mediated Activation of Rat Basophilic Leukemia Cells by Clostridium difficile Toxin B (Monoglucosyltransferase)

1996

Abstract Treatment of rat basophilic leukemia (RBL) 2H3-hm1 cells with Clostridium difficile toxin B (2 ng/ml), which reportedly depolymerizes the actin cytoskeleton, blocked [3H]serotonin release induced by 2,4-dinitrophenyl-bovine serum albumin, carbachol, mastoparan, and reduced ionophore A23187-stimulated degranulation by about 55-60%. In lysates of RBL cells, toxin B 14C-glucosylated two major and one minor protein. By using two-dimensional gel electrophoresis and immunoblotting, RhoA and Cdc42 were identified as protein substrates of toxin B. In contrast to toxin B, Clostridium botulinum transferase C3 that selectively inactivates RhoA by ADP-ribosylation did not inhibit degranulation…

Infections caused by Pseudomonas aeruginosa: relatively frequent isolation of serogroup 12 from clinical specimens.

1985

Serological typing of P. aeruginosa is the most simple and reliable procedure recommended for ≪ in-house ≫ investigations and for studies of suspected outbreaks of infection by this microorganism. It is also a useful procedure in order to know serotype prevalence in a definite geografical area and to obtain indications about the more appropriate composition of polivalent anti-Pseudomonas vaccines. In the present report, we describe the relatively high frequency of isolation of serogroup 12 from patients in Palermo, Italy. Serogroup 12 is very rare in north-Europe and in the USA, and, as a consequence, it is not included in some vaccine preparations. In Palermo, strains belonging to this ser…

Chemical composition of the essential oil of Moluccella spinosa L. (Lamiaceae) collected wild in Sicily and its activity on microorganisms affecting …

2015

In this study the chemical composition of the essential oil from aerial parts of Moluccella spinosa L. collected in Sicily was evaluated by GC and GC-MS. The main components of M. spinosa L. were α-pinene (26.6%), caryophyllene oxide (16.8%) and β-caryophyllene (8.6%). A comparison with other studied oils of genus Moluccella is made. Antibacterial and antifungal activities against some microorganisms infesting historical textiles were also determined.

The synergistic effect of SAHA and parthenolide in MDA-MB231 breast cancer cells

2014

Abstract: The sesquiterpene lactone Parthenolide (PN) exerted a cytotoxic effect on MDA-MB231 cells, a triple-negative breast cancer (TNBC) cell line, but its effectiveness was scarce when employed at low doses. This represents an obstacle for a therapeutic utilization of PN. In order to overcome this difficulty we associated to PN the suberoylanilide hydroxamic acid (SAHA), an histone deacetylase inhibitor. Our results show that SAHA synergistically sensitized MDA-MB231 cells to the cytotoxic effect of PN. It is noteworthy that treatment with PN alone stimulated the survival pathway Akt/mTOR and the consequent nuclear translocation of Nrf2, while treatment with SAHA alone induced autophagi…

Attività Antiossidanti di Capparis Spinosa e Confronto tra Aree Vulcaniche del Mediterraneo

2012

Le isole Pelagie: un luogo straordinario anche per la fauna.

2015

Lampedusa e Linosa sono isole molto diverse fra loro, una calcarea, l’altra vulcanica; quindi è comprensibile che la fauna sia in buona parte differente. Tuttavia la maggioranza delle specie vi sono migrate attivamente o, nel caso di Lampedusa, rappresentano la testimonianza di un antico collegamento con la Tunisia. L’importanza faunistica delle Pelagie è dovuta ai taxa endemici ma anche alla presenza di specie africane al limite geografico della loro distribuzione (Lampedusa, di natura calcarea, si trova infatti sulla piattaforma continentale africana).

È possibile il biologico per le olive da mensa?

2017

La frontiera dell’olivicoltura biologica da mensa passa attraverso il controllo della mosca delle olive in aree pandacie a forte pressione del dittero. In queste aree è di grande ausilio l’irrigazione, che facendo raggiungere prima la pezzatura desiderata, consente di sfuggire in parte alle più dannose infestazioni d’inizio autunno; in assenza d’irrigazione, spesso le drupe, all’arrivo delle piogge, aumentano in volume insieme alle infestazioni. I mezzi di controllo suggeriti sono quasi totalmente volti a evitare l’attacco, mediante l’uccisione degli adulti (catture massali o “attract and kill”) o la repellenza (argille e composti del rame); se si esclude l’uccisione delle larve di prima …

The biological control applied in Citrus orchards against harmful exotic pests in Sicily (Italy)

2018

The citrus groves are injured by infestations caused by indigenous species or old and new phytophagous introduced. Several problems have found in the biological control a optimal solution that allowed a considerable reduction in the use of chemical products. In fact, applications of programs using biological methods has been more successful on citrus than in any other cropping system. Sicily (Italy), due to its location in the Mediterranean Sea, represents an island particularly rich flora and fauna with a characteristic biodiversity different from those of other countries and regions of Italy. It produces about 60% of the national citrus production with more areas of organic citrus groves.…

Rhagoletis cerasi (L.) in Western Sicily: presence, damages and control in cherry orchards.

2012

The research was carried out from 2006 to 2010 in 12 cherry orchards in Western Sicily, were Rhagoletis cerasi (L.), the cherry fly, represents a problem for medium late ripening cultivars. Presence and infestation of the dipteran were monitored on local cultivars and effectiveness of some products allowed in organic farming was tested compared with net bags. The presence of the cherry fly was recorded in all cherry orchards except in two recently planted and isolated. The infestation on fruits was not very high until the end of May. Pyrethrum and spinosad did not lower the infestation, on the contrary nets reduced it.

Strategie di controllo di Bactrocera oleae (Rossi) con metodi alternativi agli interventi convenzionali in oliveti biologici della Sicilia occidentale

2011

This work reports studies on the population dynamics and safe control strategies of Bactrocera oleae in four unsprayed olive groves of western Sicily from 2007 to 2010. The main management tools for B. oleae evaluated were the“Attract and Kill” lures (Ecotrap Vioryl), the use of sardines (traditional practice) and Nu-lure (innovative) and the spinosad (innovative) which is a selective insect control product produced by the fermentation of a naturally occurring soil bacterium, Saccharopolyspora spinosa. Flies trend were carried out by pheromone traps and the level of infestation counting the number of fruits with pest eggs, larvae and pupae and hole hatching. Results showed that in all olive…