Search results for "iNOS"
showing 10 items of 2075 documents
A case report of double etiology of ecthyma gangrenosum
2019
Abstract Rationale: Ecthyma gangrenosum is a cutaneous infection, most commonly occurring during sepsis evolution with Pseudomonas aeruginosa on an immunocompromised background. There have been rare case reports in previously healthy children and rarer are the cases with double etiology. Patient concerns: We present the case of a female Caucasian patient, aged 1 year and 8 months, who developed severe sepsis during flu evolution with predominant respiratory and cerebral manifestations. On admission, at skin level, there was noticed a necrotic coccygeal ulceration (with rapid increasing dimensions 0.5/0.5 cm in 24 hours), and with the transformation from a dry necrosis in a sphacelus at the …
Shanghai Fever: Not Only an Asian Disease
2022
Objectives: To describe a case of Shanghai fever disease and to analyze other published reports in non-Asiatic countries, defining clinical characteristics and highlighting that this is not only an Asian disease. Study design: A computerized search without language restriction was conducted using PubMed and Scopus; all references listed were hand-searched to identify any other relevant literature. An article was considered eligible for inclusion in the systematic review if it reported cases with Shanghai fever described in non-Asiatic countries. Our case was also included in the analysis. Results: Ten articles reporting 10 cases of Shanghai fever disease were considered. Fever, diarrhea and…
Effect of a cyanobacterial diet on the competition between rotifers: a case study in Lake Albufera of Valencia, Spain
2019
espanolBrachionus havanaensis se distribuye predominantemente en las regiones Neartica y Neotropical. Ahora se encuentra incluso en las regiones Paleartica y Oriental. Durante el verano de 2015, encontramos altas densidades (> 500 ind./l) de esta especie y bajas abundancias de Brachionus angularis en la laguna de la Albufera, donde la cianobacteria (Microcystis aeruginosa) fue dominante en la comunidad de fitoplancton. Nuestra hipotesis fue que la cianobacteria era toxica para B. angularis pero no para B. havanaensis, por lo que este ultimo superaria al primero en presencia de dicha cianobacteria. Para probar la hipotesis, realizamos experimentos de competencia entre estas dos especies de r…
Response to salinity stress of Rhizobium leguminosarum bv. viciae strains in the presence of different legume host plants
2011
We investigated the effect of residual salts from the previous summer’s irrigation on two non-irrigated cover crops—broad bean and common vetch—and on their rhizobial symbiontics. Before sowing, seeds were inoculated with a salt-tolerant strain and a salt-sensitive strain of Rhizobium leguminosarum biovar viciae. An increase in the electrical conductivity of the saturated-soil extract from 2.0 dS m−1 to 6.0 dS m−1 caused a severe reduction of broad bean biomass, while growth of common vetch was almost unaffected by the salinity level. Our results clearly indicate that common vetch as a cover crop may increase the availability of nitrogen in soil more than broad bean also in saline environme…
Visual defects in subjects with Down’s syndrome
1995
Because the incidence of other visual defects is much higher in cases of Down’s syndrome than in individuals with other forms of retardation (Gardiner, 1967; Aitchison et al., 1990), we tested the color vision of a population of Down’s syndrome patients, using Ishihara plates and the Davico anomaloscope. The Down’s syndrome group had a significantly higher proportion of color deficiencies than either normal controls or a matched mentally retarded population. Refractive errors were corrected with static retinoscopy, and spatial contrast sensitivity was measured with the Vistech test.
Zileņu (Vaccinium uliginosum L.), melleņu (Vaccinium myrtillus L.) un krūmelleņu (Vaccinium corymbosum) ķīmiskais sastāvs un bioloģiskā aktivitāte
2015
Zileņu Vaccinium uliginosum L. un melleņu Vaccinium myrtillus L. izplatība ir Eiropas ziemeļu augsto purvu un mitro mežu areālā, skuju koku un jaukto koku mežos, īpaši retainēs un izcirtumos, savukārt krūmellenes Vaccinium corymbosum tiek audzētas kā kultūraugi. Ķīmiskais sastāvs un bioloģiskā aktivitāte, kā arī dažādu vitamīnu un vielu saturs, ogās ir ļoti augsts. Zilās ogas potenciāli labvēlīgi iedarbojas uz cilvēku veselību gan kā profilakses līdzeklis, gan kā ārstniecības līdzeklis. Neskatoties uz zileņu labajām īpašībām, cilvēku vidū lielāku popularitāti ir ieguvušas mellenes un krūmmellenes, kura bieži tiek jauktas ar zileni, tāpēc Vaccinium uliginosum L. ir maz pētīta suga. Bakalaura…
Nuclear calcium signaling by inositol trisphosphate in GH3 pituitary cells
2008
It has been proposed that nuclear and cytosolic Ca2+ ([Ca2+]N and [Ca2+]C) may be regulated independently. We address here the issue of whether inositol trisphosphate (IP3) can, bypassing changes of [Ca2+]C, produce direct release of Ca2+ into the nucleoplasm. We have used targeted aequorins to selectively measure and compare the changes in [Ca2+]C and [Ca2+]N induced by IP3 in GH3 pituitary cells. Heparin, an IP3 inhibitor that does not permeate the nuclear pores, abolished the [Ca2+]C peaks but inhibited only partly the [Ca2+]N peaks. The permeant inhibitor 2-aminoethoxy-diphenyl-borate (2-APB) blocked both responses. Removal of ATP also inhibited more strongly the [Ca2+]C than [Ca2+]N pe…
Prolactin supplementation to culture medium improves beta-cell survival
2010
OBJECTIVES.: Recent studies demonstrated that prolactin (PRL) has beneficial effects on β cells for islet transplantation. We examined the effect of human recombinant PRL (rhPRL) supplementation to the culture media to determine its potential use in the context of clinical islet transplantation. MATERIALS AND METHODS.: Each human islet isolated from 14 deceased multiorgan donors was cultured in Miami modified media-1 supplemented with or without rhPRL (500 μg/L) for 48 hr. β-Cell survival and proliferation (BrdU and Ki-67) were determined by laser scanning cytometry. The cytoprotective effects of rhPRL against noxious stimuli were assessed by flow cytometry (tetramethylrhodamine ethyl ester…
Comparative study of molecular processes and factors affecting endometrial function in subfertile patients with uterine disorders
2021
El endometrio humano es un tejido dinámico y complejo que solo es receptivo al embrión durante un corto periodo de tiempo. Por lo tanto, la identificación de trastornos y factores que impidan que el endometrio adquiera un fenotipo receptivo es crucial para poder prevenir fallos de implantación embrionaria y aumentar las tasas de embarazo. Los trastornos uterinos son complejos, multifactoriales y poligénicos y a menudo comprometen la fertilidad femenina, aunque se desconoce con exactitud cómo afectan a la adquisición de la receptividad endometrial. Además, estos trastornos carecen actualmente de un tratamiento efectivo, a menudo presentan comorbilidad entre ellos y su incidencia aumenta con …
Alquinilación conjugada enantioselectiva de compuestos carbonílicos a,b-insaturados
2015
En los últimos años se ha dedicado un considerable esfuerzo hacia el desarrollo de reacciones de adición conjugada catalítica enantioselectiva de alquinos terminales a compuestos electrofílicos proquirales. Estos procedimientos proporcionan una forma sencilla de sintetizar compuestos con un centro estereogénico propargílico. Existen numerosos ejemplos de reacciones de alquinilación a compuestos carbonílicos e iminas, obteniendo alcoholes y aminas propargílicas respectivamente. Sin embargo, la alquinilación de compuestos carbonílicos α,β-insaturados ha sido menos estudiada. En los capítulos introductorios de la presente tesis se encuentra un estudio detallado de la bibliografía más relevante…