Search results for "iNOS"

Segmentation and Navigation Support of Clinical Data Sets to Simulate the Bronchoscopy and Rhinoscopy

2007

A training and simulation system for therapy planning is developed based on patient specific imaging data. A real endoscope is used for navigation through the virtual patient. For this purpose sensors were built in the endoscope in order to track the translation, rotation and the angle of the distal end. Pre-processing (segmentation, tissue characterization) speeds-up the volume rendering up to real-time. Collision detection enables a realistic fly through the virtual patient.

Algorithms for skiascopy measurement automatization

2014

Automatic dynamic infrared retinoscope was developed, which allows to run procedure at a much higher rate. Our system uses a USB image sensor with up to 180 Hz refresh rate equipped with a long focus objective and 850 nm infrared light emitting diode as light source. Two servo motors driven by microprocessor control the rotation of semitransparent mirror and motion of retinoscope chassis. Image of eye pupil reflex is captured via software and analyzed along the horizontal plane. Algorithm for automatic accommodative state analysis is developed based on the intensity changes of the fundus reflex.

Contamination of a hospital plumbing system by persister cells of a copper-tolerant high-risk clone of Pseudomonas aeruginosa

2019

Abstract Background Pseudomonas aeruginosa (PA) is an important opportunistic pathogen that thrives best in the distal elements of plumbing and waste-water systems. Although nosocomial outbreaks of PA have been associated with water sources, the role of the plumbing system of healthcare premises as a reservoir for this pathogen is still unclear. Materials and methods We collected water samples from 12 technical areas, distant from any medical activity, in a teaching hospital in France once a week for 11 weeks. We used a method that resuscitates persister cells because of the nutrient-poor conditions and the presence of inhibitors (e.g. chlorine and copper ions). Briefly, water was sampled i…

Risk of bacillus cereus and pseudomonas aeruginosa nosocomial infections in a burns centre: the microbiological monitoring of water supplies for a pr…

1995

Opportunist bacteria are a potentially very serious problem in hospital burns units, particularly where the quantity and quality of water supplies may not be reliable, and patients are especially vulnerable. A programme of routine microbiological monitoring is described which minimises the risk to patients.

Formation of Levan from Raffinose by Levansucrase ofZymomonas mobilis

2004

Levansucrase (EC 2.4.1.10.) of Zymomonas mobilis 113S can perform the polymerisation of fructose moiety from raffinose to levan concomitantly with a release of non-catabolised melibiose into the medium. The kinetic parameters of the levansucrase-catalysed reaction provide even higher reaction velocities on raffinose as compared to sucrose, particularly at low substrate concentrations. A decreased value in the number of the average molecular mass (Mn = 1693 kDa), an increased intrinsic viscosity (η = 49.47 cm3/g), and a diminished Huggin's constant (K' = 0.67) are intrinsic to the levan synthesis from raffinose, indicating certain structural peculiarities compared to a polysaccharide obtaine…

Giant Epitheliomas: our clinical experience

2012

Combined Bacteriophage and Antibiotic Treatment Prevents Pseudomonas aeruginosa Infection of Wild Type and cftr- Epithelial Cells

2020

International audience; With the increase of infections due to multidrug resistant bacterial pathogens and the shortage of antimicrobial molecules with novel targets, interest in bacteriophages as a therapeutic option has regained much attraction. Before the launch of future clinical trials, in vitro studies are required to better evaluate the efficacies and potential pitfalls of such therapies. Here we studied in an ex vivo human airway epithelial cell line model the efficacy of phage and ciprofloxacin alone and in combination to treat infection by Pseudomonas aeruginosa. The Calu-3 cell line and the isogenic CFTR knock down cell line (cftr-) infected apically with P. aeruginosa strain PAO…

Erythrina viarum Tod. (Leguminosae) from the Palermo Botanical Garden

2011

The type of Erythrina viarum Tod. (Leguminosae) is designated and the relationship between this and other species of Erythrina Sect. Caffrae Codd is investigated. The correct name of E. viarum is E. caffra Thunb.

Expresión diferencial de proteínas en el íleon de ratón asociadas con el desarrollo de infecciones crónicas por Echinostoma caproni

2015

Entre las enfermedades parasitarias que afectan a la humanidad, las helmintiasis intestinales destacan por su gran morbilidad, ya que actualmente afectan a más de 2000 millones de personas y causan grandes pérdidas económicas relacionadas con la ganadería y la veterinaria. Echinostoma caproni es un trematodo intestinal que, por sus características, es utilizado en numerosos estudios como modelo experimental para determinar los factores por los que se resuelve una infección aguda o se desarrolla una infección crónica causada por helmintos intestinales. En este trabajo se analizó la expresión diferencial de proteínas durante una primoinfección, después de un tratamiento farmacológico y durant…

Extracellular Hsp70 Enhances Mesoangioblast Migration via an Autocrine Signaling Pathway

2016

Mouse mesoangioblasts are vessel-associated progenitor stem cells endowed with the ability of multipotent mesoderm differentiation. Therefore, they represent a promising tool in the regeneration of injured tissues. Several studies have demonstrated that homing of mesoangioblasts into blood and injured tissues are mainly controlled by cytokines/chemokines and other inflammatory factors. However, little is known about the molecular mechanisms regulating their ability to traverse the extracellular matrix (ECM). Here, we demonstrate that membrane vesicles released by mesoangioblasts contain Hsp70, and that the released Hsp70 is able to interact by an autocrine mechanism with Toll-like receptor …