Search results for "ibi"
showing 10 items of 13473 documents
I TETTI VERDI DI TIPO ESTENSIVO: BIODIVERSITÀ AD ALTA QUOTA
2016
Le città sono state paragonate da Odum a degli organismi eterotrofi che basano la loro crescita ed espansione sull’uso indiscriminato di risorse e sono causa di perdita irreversibile e frammentazione degli habitat naturali. I tetti verdi rappresentano uno strumento essenziale di mitigazione e compensazione ambientale all’interno del tessuto urbano dove, l’alta densità edilizia e l’elevato disturbo antropico concedono poco spazio alle dinamiche naturali. In particolare, i tetti verdi per la biodiversità caratterizzati da mosaici di micro-habitat diversi e contigui tra loro, possano ospitare specie con caratteristiche morfo-funzionali diverse. L’approccio noto come habitat template, consiste …
The museum setup in the benedictine dormitory of monreale: The artworks of Santa Maria Del Bosco and the textile artefacts of the Cathedral, Sicily, …
2018
The recent decision to convert the Benedictine Dormitory in Monreale into an exhibition site offers the opportunity to enjoy the whole monumental complex where the wonderful cloister is the core attraction. It is on this site that the Norman Cathedral stands, brightly decorated with golden mosaics. The new exhibition has gathered together the artworks from the ruined abbey of Santa Maria del Bosco in Calatamauro and added them to the artefacts already exhibited at the Diocesan Museum. They include marble gravestones from the 16th-17th century church and those dating to the 18th century; one stone is in polychrome marble of the family of the canons, Candes and Donato; another was used for th…
Progetto di restauro, per la fruizione e la valorizzazione della chiesa di Santa Maria in Valverde
2021
The essay presents the methodological process used for the analysis of the state of conservation and of the accessibility problems present in the church of Santa Maria in Valverde in Palermo, built in the 17th century. XVII, above previous stratifications. Furthermore, the essay shows a proposal for restoration and accessibility to the same church which in the past had a churchyard that was eliminated after the mid-twentieth century to connect the street levels. The research was conducted within the Restoration and Theory and History of Restoration Laboratory and involved the students of the LM4 course in Architecture of the Palermo Department. The suggested solution was to rebuild a new ch…
Pressure-Dependent Tuning of Photoluminescence and Size Distribution of Carbon Nanodots for Theranostic Anticancer Applications
2020
Carbon nanodots (CDs) have recently attracted attention in the field of nanomedicine because of the biocompatibility, cost-effective nature, high specific surface, good near infrared (NIR) photothermal conversion into heat and tunable fluorescence properties, which have paved the way toward incorporating use of CDs into innovative anticancer theranostic platforms. However, a reliable synthesis of CDs with established and controlled physiochemical proprieties is precluded owing to the lack of full manipulation of thermodynamic parameters during the synthesis, thus limiting their use in real world medical applications. Herein, we developed a robust solvothermal protocol which allow fine contr…
Estudio del mecanismo de reacción e inhibición de cisteína proteasas mediante métodos multiescala
2022
En esta tesis doctoral se realizaron estudios computacionales para las enzimas caspasa-1 y la 3CLpro del SARS-CoV-2. Estas enzimas pertenecen a la familia de las cisteína proteasas, las cuales hidrolizan sus respectivos sustratos rompiendo un enlace peptídico en particular. En esta reacción interviene una diada catalítica conformada por un par Cis-His. La caspasa-1 fue seleccionada debido a su importancia farmacológica en la enfermedad de Alzheimer, y la enzima 3CLpro del SARS-CoV-2 por estar involucrada en el proceso de replicación del virus responsable de la enfermedad del COVID-19. Para ambas se realizaron estudios que ayudaron a racionalizar el mecanismo de reacción con su sustrato natu…
The (im)possible success of disadvantaged students. Reflections on education, migration and social change
2019
The paper focuses on the ?unexpected pathways? of successful students with an immigrant background: these biographical routes, that seems socially impossible, raise theoretical issues around the individual-society, actor-structure relationship. Disadvantaged students who succeed represent a sociological challenge in the attempt to understand atypical situations and to identify the institutional processes and the structural opportunities that facilitate them, reducing ethnic inequalities in education. This framework is the starting point of the Su.Per. project (Success in educational pathways of students with immigrant background), based on the collection of written autobiographies of 65 imm…
Thiazole Analogues of the Marine Alkaloid Nortopsentin as Inhibitors of Bacterial Biofilm Formation
2020
Anti-virulence strategy is currently considered a promising approach to overcome the global threat of the antibiotic resistance. Among different bacterial virulence factors, the biofilm formation is recognized as one of the most relevant. Considering the high and growing percentage of multi-drug resistant infections that are biofilm-mediated, new therapeutic agents capable of counteracting the formation of biofilms are urgently required. In this scenario, a new series of 18 thiazole derivatives was efficiently synthesized and evaluated for its ability to inhibit biofilm formation against the Gram-positive bacterial reference strains Staphylococcus aureus ATCC 25923 and S. aureus ATCC 6538 a…
Synthesis, antiproliferative activity, and in silico insights of new 3-benzoylamino-benzo[ b ]thiophene derivatives
2014
A new series of 3-benzoylamino-5-imidazol-5-yl-benzo[b]thiophenes and the parent amino derivatives were synthesized and screened as antitumor agents. All tested compounds showed concentration-dependent antiproliferative activity profile against HeLa cell line, exhibiting GI50 values in the low micromolar range. The most active compounds were tested in cell cycle perturbation experiments. A rapid accumulation of cells in the G2/M phase, with a concomitant reduction of cells in both the S and G0/G1 phases, was observed, suggesting that cell exposure to selected derivatives produces mitotic failure. To rationalize the biological results, the 3-benzoylamino-benzo[b]thiophenes were analyzed thro…
Adolescents' credibility justifications when evaluating online texts.
2022
AbstractResearch has shown that students differ in their abilities to evaluate the credibility of online texts, and, in general, many perform poorly on online evaluation tasks. This study extended current knowledge by examining students’ abilities to justify the credibility of online texts from different perspectives, thus providing a more nuanced understanding of students’ credibility evaluation ability. We examined how upper secondary school students (N = 73; aged 16 to 17) evaluated author expertise, author intention, the publication venue, and the quality of evidence when reading four texts about the effects of sugar consumption in a web-based environment. Additionally, we examined how …
Translation and dealing with “the other” in scholarly research and publishing:
2022
Although languages other than English, along with various forms of translation, are intrinsic to multilingual researchers’ scholarly activities, they generally remain less visible in English-medium publications. In this discussion paper, I explore this topic from a broader sociopolitical perspective by looking at the use and function of translation in various stages of research and writing for publication. Drawing on recent studies on multilingualism in academia and my own experience as a teacher of research communication, I argue that in the academic context, translation cannot be seen as a mere linguistic act or a communication tool as it is inextricably tied to complex and multilayered c…