Search results for "ichen"

showing 10 items of 338 documents

Quality of life in erosive oral lichen planus patients treated with clobetasol mucoadhesive formulations – a pilot study

2017

Oral lichen planus OLP Clobetasol quality of life
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Where do you live? North versus Central-South differences in relation to Italian patients with oral lichen planus: a cross-sectional study from the S…

2022

Abstract Background Oral lichen planus (OLP) is an immune-mediated inflammatory chronic disease of the oral mucosa, with different patterns of clinical manifestations which range from keratotic manifestations (K-OLP) to predominantly non-keratotic lesions (nK-OLP). The aim of the study was to analyze the differences in the clinical, psychological profile and symptoms between Italian patients of the North and Central-South with K-OLP and nK-OLP. Methods 270 K-OLP and 270 nK-OLP patients were recruited in 15 Italian universities. The Numeric Rating Scale (NRS), Total Pain Rating Index (T-PRI), Hamilton Rating Scales for Depression and for Anxiety (HAM-D and HAM-A), Pittsburgh Sleep Quality In…

OralCross-Sectional StudieLichen PlanusItaly; Oral lichen planus; Pain; Psychological profile; Sleep disturbancesSleep disturbancePainSleep disturbancesAnxietySettore MED/28 - MALATTIE ODONTOSTOMATOLOGICHECross-Sectional StudiesOral lichen planuItalyPsychological profileItaly; Oral lichen planus; Pain; Psychological profile; Sleep disturbances; Anxiety; Cross-Sectional Studies; Humans; Pain; Pathology Oral; Lichen Planus OralOral lichen planusPathologyPathology OralHumansGeneral DentistryHumanLichen Planus Oral
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Assessment of sleep disturbance in oral lichen planus and validation of PSQI: A case-control multicenter study from the SIPMO (Italian Society of Ora…

2021

Background: The wellbeing of oral lichen planus patients (OLPs) may be strongly influenced by a poor quality of sleep (QoS) and psychological impairment. The aims were to analyze the prevalence of sleep disturbance, anxiety, and depression in OLPs and to validate the Pittsburgh Sleep Quality Index (PSQI) in OLPs. Methods: Three hundred keratotic OLPs (K-OLPs), 300 with predominant non-keratotic OLP (nK-OLPs), and 300 controls were recruited in 15 Italian universities. The PSQI, Epworth Sleepiness Scale (ESS), Hamilton Rating Scales for Depression and Anxiety (HAM-D and HAM-A), Numeric Rating Scale (NRS), and Total Pain Rating Index (T-PRI) were administered. Results: Oral lichen planus pati…

OralSleep Wake DisordersCancer Researchmedicine.medical_specialtyanxiety; insomnia; mood disturbance; oral lichen planus; sleep disturbance; Anxiety; Case-Control Studies; Depression; Female; Humans; Pathology Oral; Reproducibility of Results; Sleep; Surveys and Questionnaires; Lichen Planus Oral; Sleep Wake DisordersinsomniaReproducibility of Resultoral lichen planuPathology and Forensic MedicineSettore MED/28 - MALATTIE ODONTOSTOMATOLOGICHEPittsburgh Sleep Quality Indexoral lichen planusstomatognathic systemSurveys and QuestionnairesInsomniamedicineNumeric Rating ScalePathologySurveys and QuestionnaireHumansanxiety; insomnia; mood disturbance; oral lichen planus; sleep disturbancemood disturbanceSleep disorderbusiness.industryDepressionEpworth Sleepiness ScaleLichen PlanusReproducibility of ResultsRating scales for depressionmedicine.diseaseanxietysleep disturbancehumanitiesstomatognathic diseasesOtorhinolaryngologyCase-Control StudiesPathology OralPhysical therapyPeriodonticsAnxietyOral lichen planusFemaleOral Surgerymedicine.symptomCase-Control StudiebusinessSleepHumanLichen Planus Oral
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Efficacy of ozonized water for the treatment of erosive oral lichen planus : a randomized controlled study

2020

Background Management of erosive Oral Lichen Planus (eOLP) is challenging. Currently, topical corticosteroids are widely used as first-line therapy, but they might be associated with side-effects and incomplete clinical response. Among non-pharmacological strategies, ozone at low medical concentration has proven to induce a mild activation of protective anti-oxidant pathways, thus exerting therapeutic effects in many inflammatory diseases. The aim of this randomized controlled study was to investigate the effectiveness of ozonized water in association with conventional topical corticosteroids for the treatment of eOLP. Material and Methods Fifty-one patients were included in the study and r…

Oralmedicine.medical_specialtyLichensmedicine.drug_classAdministration TopicalPlacebo treatmentLichenGastroenterologyOLPlaw.invention03 medical and health sciencesErosive oral lichen planusOzone0302 clinical medicineRandomized controlled trialChronic Disease; Humans; Lichen Planus Oral; Water; LichenlawAdrenal Cortex HormonesInternal medicineMedicineHumansGeneral DentistryOral Medicine and Pathologybusiness.industrySize reductionResearchTherapeutic effectLichen PlanusWater030206 dentistry:CIENCIAS MÉDICAS [UNESCO]TreatmentOtorhinolaryngologyChronic DiseaseUNESCO::CIENCIAS MÉDICASOral rinsesCorticosteroidBetamethasoneSurgeryOral Lichen PlanusbusinessOLP; Oral Lichen Planus; Ozone; Treatmentmedicine.drugLichen Planus Oral
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Validation of microRNA expression profile in Oral Lichenoid Disease through cytological samples

2019

Background To validate oral exfoliative cytology in the analysis of the microRNA expression profile in Oral Lichenoid Disease (OLD).

Pathologymedicine.medical_specialtyDiseaseReal-Time Polymerase Chain Reaction03 medical and health sciences0302 clinical medicinemicroRNABiopsymedicineTaqManHumansOral mucosaGeneral DentistryOral Medicine and Pathologymedicine.diagnostic_testbusiness.industryGene Expression ProfilingResearch030206 dentistryMicroRNA Expression ProfileSmall interfering RNA:CIENCIAS MÉDICAS [UNESCO]Gene expression profilingMicroRNAsstomatognathic diseasesmedicine.anatomical_structureReal-time polymerase chain reactionOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASEpigeneticsSurgeryLichen planusbusinessMouth Diseases
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Cytomorphometric analysis of squames from oral premalignant and malignant lesions

2011

Objective: Oral cytology is becoming increasingly important in the early diagnosis of oral cancer, including epithelial atypia. The aim of this study is to assess the whether the cytoplasmic diameter, nuclear diameter and their nuclear to cytoplasmic ratio are reliable parameters in exfoliative cytology in detecting premalignant and malignant lesions. Study design: Cell and nuclear diameter were measured from the squames of normal buccal mucosal and of oral leukoplakia, oral submucous fibrosis, oral lichen planus which were histologically benign and oral squamous cell carcinoma were measured using an ocular micrometer disc. The nuclear to cytoplasmic ratio in each of these were deduced from…

Pathologymedicine.medical_specialtyOcular micrometerbusiness.industryCancerOdontologíaBuccal administrationEpithelial atypiamedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludOral leukoplakiastomatognathic diseasesOral submucous fibrosisCytologyUNESCO::CIENCIAS MÉDICASMedicineOral lichen planusbusinessGeneral Dentistry
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Prevalence of oral lichen planus among a sample of the Egyptian population

2015

Objectives: To report on the prevalence of oral lichen planus among a sample of the Egyptian population. Study Design: 4470 Egyptian patients, aged 15-75 years, were seen at the outpatient clinic at the Faculty of Oral and Dental Medicine, Cairo University, Egypt. 31.25 % of these patients were males and 68.75% were females. Oral mucosal lesions consistent with oral lichen planus (OLP) were identified both clinically and confirmed histo - logically (in atypical cases) so that the prevalence of oral lichen planus in this study is 1.43%. Results: 64 patients were diagnosed with OLP (20 males and 44 females). The average age of the affected group was 48.07 years. Associated skin lesions were d…

Pathologymedicine.medical_specialtyPopulationOdontologíaLesionstomatognathic systemDiabetes mellitusmedicineOutpatient clinicBasal celleducationGeneral Dentistryeducation.field_of_studyOral Medicine and Pathologyintegumentary systembusiness.industryResearchCirculating antibodiesOral mucosal lesionsmedicine.disease:CIENCIAS MÉDICAS [UNESCO]DermatologyCiencias de la saludstomatognathic diseasesUNESCO::CIENCIAS MÉDICASOral lichen planusmedicine.symptombusiness
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A retrospective study of 171 patients with oral lichen planus in the East Bohemia - Czech Republic - single center experience.

2014

Objectives: Oral lichen planus is chronic inflammatory disease with a high prevalence in the population. This study describes the epidemiological and clinical characteristics of group of patients with oral lichen planus in the Czech Republic. Material and Methods: Data was taken from the medical records of 171 patients referred to the Oral Medicine Unit at the University Hospital in Hradec Kralove with histologically confirmed clinical diagnosis of oral lichen planus in the period 2003 – 2013. The data were retrospectively reviewed. Results: Of the 171 patients, 116 (67.8%) were women and 55 (32.2%) were men. The mean age was 55.2 ± 12.4 years (range of 85.0 – 20.9). The reticular form was …

Pathologymedicine.medical_specialtyPopulationOdontologíaSingle CenterAsymptomaticstomatognathic systemEpidemiologyMedicineeducationGeneral Dentistryeducation.field_of_studyOral Medicine and Pathologybusiness.industryResearchRetrospective cohort studymedicine.disease:CIENCIAS MÉDICAS [UNESCO]DermatologyCiencias de la saludDesquamative gingivitisstomatognathic diseasesUNESCO::CIENCIAS MÉDICASOral lichen planusmedicine.symptombusinessOral medicineJournal of clinical and experimental dentistry
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Efficacy of photodynamic therapy in vulvar lichen sclerosus treatment based on immunohistochemical analysis of CD34, CD44, myelin basic protein, and …

2010

Introduction:Lichen sclerosus (LS) is a chronic skin and mucosa inflammatory disease. It affects mainly the female anogenital area especially in postmenopausal period. The main symptoms include pruritus, burning, pain, sometimes urinary problems, or difficulties in defecation. Usually, porcelain-white plaques are seen in the skin and mucosa. The etiology and pathogenesis of LS are still uncertain. There are some research studies on possible genetic predisposition, yet autoimmune, hormonal, or infectious factors are not excluded. The typical treatment of LS is mainly pharmacological, although the alternative treatment method used in LS is photodynamic therapy (PDT), which is noninvasive tech…

Pathologymedicine.medical_specialtyProliferation indexmedicine.medical_treatmentPhotodynamic therapyAntigens CD34Lichen sclerosusVulvar Lichen SclerosusPhotodynamic therapyVulvaPathogenesisGenetic predispositionmedicineHumansVulvar Lichen Sclerosusbiologybusiness.industryObstetrics and GynecologyMyelin Basic ProteinMiddle Agedmedicine.diseaseLichen sclerosusImmunohistochemistryMyelin basic proteinHyaluronan ReceptorsKi-67 AntigenTreatment OutcomeOncologyPhotochemotherapybiology.proteinImmunohistochemistryFemalebusinessInternational Journal of Gynecological Cancer
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Cytometric analysis of oral scrapings of patients with oral lichen planus

2011

A. Acha-Sagredo, Y. Jimenez, J. V. Bagan, M. A. Echebarria-Goicouria and J. M. Aguirre-Utric analysis of oral scrapings of patients with oral lichen planus Objective:  Aneuploidy has been associated with malignant and premalignant oral lesions. In the past few years, its application in oral precancerous lesions and its prognostic meaning have been controversial issues. The aim of our study was to characterize alterations in DNA content by automated DNA image cytometry in oral scrapings of patients with oral lichen planus. Methods:  Cytological samples from 40 patients clinicopathologically diagnosed with oral lichen planus were analysed by DNA image cytometry. Results:  All the cases were c…

Pathologymedicine.medical_specialtyeducation.field_of_studyHistologyintegumentary systembusiness.industryPopulationAneuploidyDna indexGeneral Medicinemedicine.diseasePathology and Forensic Medicinestomatognathic diseasesstomatognathic systemmedicineOral lichen planusskin and connective tissue diseasesbusinesseducationDNA Image CytometryCytopathology
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