Search results for "ideal"

Assessing optimal water quality monitoring network in road construction using integrated information-theoretic techniques

2020

Author´s accepted manuscript. The environmental impacts of road construction on the aquatic environment necessitate the monitoring of receiving water quality. The main contribution of the paper is developing a feasible methodology for spatial optimization of the water quality monitoring network (WQMN) in surface water during road construction using the field data. First, using the Canadian Council of Ministers of the Environment (CCME) method, the water quality index (WQI) was computed in each potential monitoring station during construction. Then, the integrated form of the information-theoretic techniques consists of the transinformation entropy (TE), and the value of information (VOI) we…

Evolutionary conservation advice for despotic populations: habitat heterogeneity favours conflict and reduces productivity in Seychelles magpie robins

2010

Individual preferences for good habitat are often thought to have a beneficial stabilizing effect for populations. However, if individuals preferentially compete for better-quality territories, these may become hotspots of conflict. We show that, in an endangered species, this process decreases the productivity of favoured territories to the extent that differences in productivity between territories disappear. Unlike predictions from current demographic theory on site-dependent population regulation (ideal despotic distribution), we show that population productivity is reduced if resources are distributed unevenly in space. Competition for high-quality habitat can thus have detrimental con…

An Algebraic Derivation of Chao’s Estimator of the Number of Species in a Community Highlights the Condition Allowing Chao to Deliver Centered Estima…

2014

Anne Chao proposed a very popular, nonparametric estimator of the species richness of a community, on the basis of a limited size sampling of this community. This expression was originally derived on a statistical basis as a lower-bound estimate of the number of missing species in the sample and provides accordingly a minimal threshold for the estimation of the total species richness of the community. Hereafter, we propose an alternative, algebraic derivation of Chao’s estimator, demonstrating thereby that Chao’s formulation may also provide centered estimates (and not only a lower bound threshold), provided that the sampled communities satisfy a specific type of SAD (species abundance dist…

Habitat assessment by parasitoids: consequences for population distribution

2006

International audience; The ideal free distribution (IFD) is a stable distribution of competitors among resource patches. For equally efficient competitors, equilibrium is reached when the per capita rate of intake equalizes across patches. The seminal version of the IFD assumes omniscience, but populations may still converge toward the equilibrium provided that competitors 1) accurately assess their environment by learning and 2) remain for an optimal (rate-maximizing) time on each encountered patch. In the companion article (Tentelier C, Desouhant E, Fauvergue X. 2006. Habitat assessment by parasitoids: mechanisms for patch time allocation. Behav Ecol. Forthcoming), it is shown that the p…

Coarse-grained models of double-stranded DNA based on experimentally determined knotting probabilities

2018

Abstract To accurately model double-stranded DNA in a manner that is computationally efficient, coarse-grained models of DNA are introduced, where model parameters are selected by fitting the spectrum of observable DNA knots: We develop a general method to fit free parameters of coarse-grained chain models by comparing experimentally obtained knotting probabilities of short DNA chains to knotting probabilities that are computed in Monte Carlo simulations, resulting in coarse-grained DNA models which are tailored to reflect DNA topology in the best possible way. The method is exemplified by fitting ideal chain models as well as a bead-spring model with excluded volume interactions, to model …

Characterization of the first-in-class T-cell-engaging bispecific single-chain antibody for targeted immunotherapy of solid tumors expressing the onc…

2015

abstract The fetal tight junction molecule claudin 6 (CLDN6) is virtually absent from any normal tissue, whereas it is aberrantly and frequently expressed in various cancers of high medical need. We engineered 6PHU3, a T-cell-engaging bispecific single chain molecule (bi-(scFv)2) with anti-CD3/anti-CLDN6 specificities, and characterized its pharmacodynamic properties. Our data show that upon engagement by 6PHU3, T cells strongly upregulate cytotoxicity and activation markers, proliferate and acquire an effector phenotype. 6PHU3 exerts potent killing of cancer cells in vitro with EC50 values in the pg/mL range. Subcutaneous xenograft tumors in NSG mice engrafted with human PBMCs are eradicat…

The Breast Size Satisfaction Survey (BSSS): Breast size dissatisfaction and its antecedents and outcomes in women from 40 nations

2020

The Breast Size Satisfaction Survey (BSSS) was established to assess women's breast size dissatisfaction and breasted experiences from a cross-national perspective. A total of 18,541 women were recruited from 61 research sites across 40 nations and completed measures of current-ideal breast size discrepancy, as well as measures of theorised antecedents (personality, Western and local media exposure, and proxies of socioeconomic status) and outcomes (weight and appearance dissatisfaction, breast awareness, and psychological well-being). in the total dataset, 47.5 % of women wanted larger breasts than they currently had, 23.2 % wanted smaller breasts, and 29.3 % were satisfied with their curr…

2018

Representative, legislative and deliberative assemblies are commonly called parliaments. The three types of assemblies share many procedures and practices, and the Inter-Parliamentary Union include...

Contesting Cultural Heritage: Decolonizing the Tropenmuseum as an Intervention in the Dutch/European Memory Complex

2019

AbstractThe chapter discusses how (post-)immigrant activism in the Netherlands currently impacts Dutch and European cultural heritage and their cultural archive and memory complex. The discussion focuses on the Tropenmuseum and the way postcolonial (post)immigrants carried out interventions there, resulting in new ways of visually and textually representing the colonial past. Though the end result is not a final ideal decolonized situation, it did evince de-essentializing processes in which intersectional perspectives are taken up. The interventions coincide with other national and international protests and processes, making it part of a project or movement that produces decolonial counter…

The New Soviet Man With a Female Body: Mother, Teacher, Tractor Driver…

2020

Naujojo žmogaus sukūrimo idėjos užuomazgų galima rasti senovės Graikijoje ir Romoje, taip pat utopistų, švietėjų kūriniuose, teologiniuose tekstuose, tačiau ši ideologema galutinai susiformavo XIX a. pabaigoje, o bandymai ją realizuoti praktiškai sietini su (para)totalitarizmo įsigalėjimu. Vienas iš žinomiausių tokių bandymų pavyzdžių – siekis sukurti Naująjį sovietinį žmogų. Šis bandymas nuo kitų skiriasi komunistine ideologija, kuri kiekvienam reiškiniui suteikia „papildomų reikšmių ar funkcijų“ (Prozorov, 2013, p. 210). Kitaip tariant, visus dalykus SSRS galima suprasti ir paaiškinti tik diktatūros tikslu – utopinė ateities visuomenė „komunizmas“, kurios vardu valstybė viską ir visus reg…