Search results for "idia"
showing 10 items of 673 documents
Tridiagonality, supersymmetry and non self-adjoint Hamiltonians
2019
In this paper we consider some aspects of tridiagonal, non self-adjoint, Hamiltonians and of their supersymmetric counterparts. In particular, the problem of factorization is discussed, and it is shown how the analysis of the eigenstates of these Hamiltonians produce interesting recursion formulas giving rise to biorthogonal families of vectors. Some examples are proposed, and a connection with bi-squeezed states is analyzed.
La corte Costituzionale ammette poteri sostitutivi regionali: una scelta coerente con i principi di sussidiarietà e di leale collaborazione
2004
Pyrrolidine in Drug Discovery: A Versatile Scaffold for Novel Biologically Active Compounds
2021
AbstractThe five-membered pyrrolidine ring is one of the nitrogen heterocycles used widely by medicinal chemists to obtain compounds for the treatment of human diseases. The great interest in this saturated scaffold is enhanced by (1) the possibility to efficiently explore the pharmacophore space due to sp3-hybridization, (2) the contribution to the stereochemistry of the molecule, (3) and the increased three-dimensional (3D) coverage due to the non-planarity of the ring—a phenomenon called “pseudorotation”. In this review, we report bioactive molecules with target selectivity characterized by the pyrrolidine ring and its derivatives, including pyrrolizines, pyrrolidine-2-one, pyrrolidine-2…
Oral microbiome and systemic antineoplastics in cancer treatment:a systematic review
2021
Oral mucositis is one of the most common side effects in cancer patients receiving systemic antineoplastics. However, the underlying biological mechanisms leading to this condition are still unclear. For this reason, it has been hypothesised that systemic antineoplastics may cause an imbalance on the oral microbiota that subsequently triggers oral mucosa damage. A systematic review was performed following the PRISMA protocol and the PICO question established was: patients diagnosed with cancer, who are candidates for receiving systemic antineoplastics (P=Patients), that undergo oral microbiome determinations (I=Intervention), before and after systemic antineoplastics administration (C=Compa…
Microscopic features of the tunic in young Styela canopus (Tunicata, Styelidae)
The tunic is a unique tissue in metazoans covering the epidermis of ascidians and other tunicates. The tunic is a multifunctional tissue that provides support, mechanical rigidity, and protection against infection and predation. The outermost surface of it is covered by a thin continuous layer called tunic cuticle. The tunic cuticle density and integrity must be maintained during the growth of the animal after metamorphosis, as it represents the primary body surface barrier preventing the mechanical damage. Using transmission electronic microscopy we attempted to characterize the cuticle morphology of young Styela canopus, a solitary ascidian (Styelidae), in comparison with the cuticle arch…
The role of local and regional authorities in the implementation of the european social charter
2018
URL del artículo en la web de la Revista: https://www.upo.es/revistas/index.php/lex_social/article/view/3475/2749 Le présent article met l¿accent sur le fonctionnement et les avantages des deux mécanismes de contrôle de la Charte sociale européenne (système de rapports et procédure de réclamations collectives) en termes de progrès réalisés par les États Parties dans le domaine des droits sociaux avec une action primordiale des collectivités locales et régionales, permettant ainsi de forger une conscience européenne plus solide « par le bas ». En ce sens, dans le cadre du « Processus de Turin » pour la Charte sociale européenne, les collectivités territoriales peuvent exercer une influence p…
La legislazione regionale in materia di trasporti dopo la riforma Bassanini
2002
L'articolo esamina la legislazione regionale in materia di trasporti dopo la riforma Bassanini.
The diaptomid fauna of Israel (Copepoda, Calanoida, Diaptomidae), with notes on the systematics of Arctodiaptomus similis (Baird, 1859) and Arctodiap…
2014
Background: To date, only scarce information is available about the diaptomid copepods of the Middle East despite the ecological and biogeographical importance of the family Diaptomidae in the inland waters of the Holarctic region. Moreover, the taxonomic status of some of the taxa occurring in the area is in need of revision. We studied crustaceans collected from temporary and permanent lentic water bodies in Israel with the aim of providing an updated census of the diaptomid copepods occurring in the country. Furthermore, we morphologically and genetically analysed samples of Arctodiaptomus similis s.l. to shed light on its taxonomy. Results: Five diaptomid taxa were collected during this…
Role of IFN-gamma in immune responses to Candida albicans infections
2014
Candida albicans is the most frequent etiologic agent that causes opportunistic fungal infections called candidiasis, a disease whose systemic manifestation could prove fatal and whose incidence is increasing as a result of an expanding immunocompromised population. Here we review the role of interferon-gamma (IFN-γ) in host protection against invasive candidiasis. This cytokine plays an essential role in both the innate and adaptive arms of the immune response to candidiasis. We focus on recent progress on host-pathogen interactions leading to the production of IFN-γ by host cells. IFN-γ is produced by CD4 Th1, CD8, γδ T, and natural killer (NK) cells, essentially in response to both IL-12…
Effect of Three Different Aloe vera Gel-Based Edible Coatings on the Quality of Fresh-Cut “Hayward” Kiwifruits
2020
In recent years, the market for minimally processed fruit has increased. Fresh-cut fruits are characterized by a short shelf life due to the processing phases that accelerate the ripening courses. The aim of this work is to analyze the effect on the quality of fresh-cut Hayward kiwis of three different edible coatings based on (1) Aloe vera gel, (2) Aloe vera gel + hydroxypropyl methylcellulose and (3) Aloe vera gel + lemon essential oil. Fruit firmness, weight loss, color, soluble solids content, titratable acidity, microbial load and sensory analysis were evaluated as fresh after 2, 4, 7 and 10 days. Aloe vera gel and Aloe vera gel + lemon essential oil maintained the best values, as they…