Search results for "iho"

Hydrological post-processing based on approximate Bayesian computation (ABC)

2019

[EN] This study introduces a method to quantify the conditional predictive uncertainty in hydrological post-processing contexts when it is cumbersome to calculate the likelihood (intractable likelihood). Sometimes, it can be difficult to calculate the likelihood itself in hydrological modelling, specially working with complex models or with ungauged catchments. Therefore, we propose the ABC post-processor that exchanges the requirement of calculating the likelihood function by the use of some sufficient summary statistics and synthetic datasets. The aim is to show that the conditional predictive distribution is qualitatively similar produced by the exact predictive (MCMC post-processor) or …

Iterative continuous maximum-likelihood reconstruction method

1992

GWideCodeML: A python package for testing evolutionary hypotheses at the genome-wide level

2020

One of the most widely used programs for detecting positive selection, at the molecular level, is the program codeml, which is implemented in the Phylogenetic Analysis by Maximum Likelihood (PAML) package. However, it has a limitation when it comes to genome-wide studies, as it runs on a gene-by-gene basis. Furthermore, the size of such studies will depend on the number of orthologous genes the genomes have income and these are often restricted to only account for instances where a one-to-one relationship is observed between the genomes. In this work, we present GWideCodeML, a Python package, which runs a genome-wide codeml with the option of parallelization. To maximize the number of analy…

Digital skills and application use among Finnish home care workers in the eldercare sector

2021

This chapter explores the role digital skills, interest in technology, and social support have in home care workers’ use of digital applications at work. The empirical research is based on the 2019 University of Jyväskylä survey study on eldercare work (N = 6,903), drawn from the members of four majors trade unions in Finland. In this chapter, a sub-sample of home care workers (n = 1,398) is used in the analyses. Structural equation models are used to estimate the direct and indirect effects of available technology support, digital skills, and interest in technology on the actual use of various digital applications at work. According to the results, technology support has no direct effect o…

Independent Validation of Sepsis Index for Sepsis Screening in the Emergency Department

2021

(1) Background: The early detection of sepsis is still challenging, and there is an urgent need for biomarkers that could identify patients at a high risk of developing it. We recently developed an index, namely the Sepsis Index (SI), based on the combination of two CBC parameters: monocyte distribution width (MDW) and mean monocyte volume (MMV). In this study, we sought to independently validate the performance of SI as a tool for the early detection of patients at a high risk of sepsis in the Emergency Department (ED). (2) Methods: We enrolled all consecutive patients attending the ED with a request of the CBC. MDW and MMV were measured on samples collected in K3-EDTA tubes on the UniCel …

L'art de prolonger la vie humaine

1799

Orģinālnosaukums "Kunst das menschliche Leben zu verlängern"

Temporal and spatial diversification of the African disjunct genus Androcymbium (Colchicaceae)

2009

Abstract The genus Androcymbium (Colchicaceae) includes 57 species that are distributed in the extreme northern and southern portions of Africa, mainly in regions with a Mediterranean climate. We present the first phylogeographic analysis of the genus with species from all five of its distribution areas (North Africa, Horn of Africa, Namibia, western South Africa, and eastern South Africa). We used sequence data from six chloroplast regions and one nuclear region. Phylogeographic reconstructions were conducted using both parsimony and Bayesian inference methods. Molecular dating estimates using a Bayesian approach suggest a middle Miocene (13.4 ± 1.5 mya) origin of the genus; this approach …

Miega ilguma un kvalitātes saistība ar pašnovērtētām uzmanības problēmām pieaugušo populācijā

2019

Šī pētījuma mērķis bija izpētīt, vai pastāv dzimumatšķirības miega ilgumam, miega kvalitātei un pašnovērtētām uzmanības problēmām, kā arī, vai pastāv saistības starp miega ilgumu, miega kvalitāti, pašnovērtētām uzmanības problēmām un respondentu vecumu pieaugušo populācijā. Pētījuma izlase sastāv no 113 abu dzimumu indivīdiem vecumā no 21 līdz 55 gadiem (M=28,9, SD=7,58), kuri elektroniskā veidā aizpildīja anketu, kas sastāvēja no Pitsburgas Miega Kvalitātes indeksa un Uzmanības un Snieguma Pašnovērtēšanas aptaujas. Rezultāti rāda, ka dzimumatšķirības eksistē tikai miega efektivitātes rādītājā – sievietēm ir nepieciešams mazāk laika, lai aizmigtu, un viņas miegā pavada ilgāku laiku. Pašnovē…

The complete mitochondrial genome of Bactrocera biguttula (Bezzi) (Diptera: Tephritidae) and phylogenetic relationships with other Dacini

2018

Bactrocera biguttula is an African olive fruit fly that does not attack cultivated olives but rather develops in the fruits of wild species of Olea and Noronhia. The complete mitochondrial genome of an individual specimen was characterized in comparison to other Bactrocera. The phylogenetic relationships of B. biguttula with other Dacini were investigated, with special focus on B. oleae, an agricultural pest known to attack cultivated and wild olives. The sequence had a total length of 15,829 bp, and included the typical features of insect mitogenomes, similarly to the other Bactrocera analysed. Start codons included ATG, ATC, ATT, and TCG (in COI). The majority of stop codons (TAA) were fu…

Selection on Coding Regions Determined Hox7 Genes Evolution

2003

The important role of Hox genes in determining the regionalization of the body plan of the vertebrates makes them invaluable candidates for evolutionary analyses regarding functional and morphological innovation. Gene duplication and gene loss led to a variable number of Hox genes in different vertebrate lineages. The evolutionary forces determining the conservation or loss of Hox genes are poorly understood. In this study, we show that variable selective pressures acted on Hox7 genes in different evolutionary lineages, with episodes of positive selection occurring after gene duplications. Tests for functional divergence in paralogs detected significant differentiation in a region known to …