Search results for "illness"

showing 10 items of 1529 documents

Spatial Properties of Mismatch Negativity in Patients with Disorders of Consciousness

2018

In recent decades, event-related potentials have been used for the clinical electrophysiological assessment of patients with disorders of consciousness (DOCs). In this paper, an oddball paradigm with two types of frequencydeviant stimulus (standard stimuli were pure tones of 1000 Hz; small deviant stimuli were pure tones of 1050 Hz; large deviant stimuli were pure tones of 1200 Hz) was applied to elicit mismatch negativity (MMN) in 30 patients with DOCs diagnosed using the JFK Coma Recovery ScaleRevised (CRS-R). The results showed that the peak amplitudes of MMN elicited by both large and small deviant stimuli were significantly different from baseline. In terms of the spatial properties of…

MaleMismatch negativityPhysiologyMismatch negativityNeuropsychological TestsAudiologyElectroencephalographySeverity of Illness Indexvegetative stateCorrelation0302 clinical medicineLevel of consciousnessDisorder of consciousnessEEGEvoked PotentialsOddball paradigmMinimally conscious stateVegetative statemedicine.diagnostic_testGeneral Neuroscience05 social sciencesMinimally conscious stateElectroencephalographyGeneral MedicineMiddle Agedtajuttomuusdisorder of consciousnessAuditory PerceptionConsciousness DisordersOriginal ArticleFemalePsychologyAdultmedicine.medical_specialtyAdolescentWavelet AnalysisStimulus (physiology)behavioral disciplines and activities050105 experimental psychology03 medical and health sciencesmedicineHumans0501 psychology and cognitive sciencesAgedmedicine.diseaseminimally conscious stateElectrophysiologyAcoustic StimulationBrain Injuriestajunnan tasopoikkeavuusnegatiivisuus030217 neurology & neurosurgery
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A Comparison of 2 Mitral Annuloplasty Rings for Severe Ischemic Mitral Regurgitation: Clinical and Echocardiographic Outcomes.

2016

Controversies regarding the choice of annuloplasty rings for treatment of ischemic mitral regurgitation still exist. Aim of the study is to compare early performance of 2 different rings in terms of rest and exercise echocardiographic parameters (transmitral gradient, systolic pulmonary artery pressure, and mitral valve area), clinical outcomes, and recurrence of mitral regurgitation. From January 2008 till December 2013, prospectively collected data of patients who underwent coronary artery bypass grafting and undersizing mitral valve annuloplasty for severe chronic ischemic mitral regurgitation at our Institution were reviewed. A total of 93 patients were identified; among them 44 had sem…

MaleMitral Valve AnnuloplastyTime FactorsMyocardial IschemiaHemodynamics030204 cardiovascular system & hematologySeverity of Illness IndexVentricular Function Left0302 clinical medicinePostoperative ComplicationsRecurrenceMitral valve annuloplastyMitral valve030212 general & internal medicineHospital MortalityHeart Valve Prosthesis ImplantationExercise ToleranceIschemic mitral regurgitationMitral Valve InsufficiencyGeneral MedicineMiddle Agedmedicine.anatomical_structureTreatment OutcomeItalyHeart Valve ProsthesisCardiologyMitral ValveFemaleCardiology and Cardiovascular MedicineArteryEchocardiography StressPulmonary and Respiratory Medicinemedicine.medical_specialtyProsthesis Design03 medical and health sciencesInternal medicinemedicine.arterymedicineHumansMitral AnnuloplastyAgedRetrospective StudiesMitral regurgitationbusiness.industryRecovery of FunctionSurgeryPulmonary arteryChronic DiseaseExercise TestSurgerybusinessSeminars in thoracic and cardiovascular surgery
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Six-minute walk test in moderate to severe heart failure with preserved ejection fraction: Useful for functional capacity assessment?

2015

Despite improvements in medical treatment and prevention, heart failure (HF) remains a major cause of morbidity and mortality worldwide [1]. Currently, HF with preserved ejection fraction (HFpEF) has become the most prevalent form of HF in elderly patients [2,3]. The cardinal features in HF, aside from left ventricular systolic function, are exertional dyspnea and reduced aerobic capacity. Although the most accurate expression of exercise tolerance and severity in HF is measured by peak oxygen uptake (peak VO2), its assessment is not widely available in daily clinical practice.  This work was supported in part by grants from: Sociedad Española de Cardiología: Investigación Clínica en Cardio…

MaleModerate to severeGerontologySIX MINUTE WALKmedicine.medical_specialtyCapacity assessmentSix-minute walk testWalking030204 cardiovascular system & hematologySeverity of Illness Index03 medical and health sciences0302 clinical medicineInternal medicinemedicineHumans030212 general & internal medicinePeak VO2AgedHeart Failurebusiness.industryDisease progressionStroke VolumeStroke volumemedicine.diseaseHeart failure with preserved ejection fractionHeart failureDisease ProgressionExercise TestCardiologyFunctional capacity assessmentFemaleCardiology and Cardiovascular MedicinePeak vo2Heart failure with preserved ejection fractionbusinessInternational Journal of Cardiology
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Hypomineralized Second Primary Molars as Predictor of Molar Incisor Hypomineralization

2016

AbstractMolar incisor hypomineralization (MIH) is a developmental defect of dental enamel that shares features with hypomineralized second primary molars (HSPM). Prior to permanent tooth eruption, second primary molars could have predictive value for permanent molar and incisor hypomineralization. To assess this possible relationship, a cross-sectional study was conducted in a sample of 414 children aged 8 and 9 years from the INMA cohort in Valencia (Spain). A calibrated examiner (linear-weighted Kappa 0.83) performed the intraoral examinations at the University of Valencia between November 2013 and 2014, applying the diagnostic criteria for MIH and HSPM adopted by the European Academy of …

MaleMolarDentistrySeverity of Illness IndexLikelihood ratios in diagnostic testingArticle03 medical and health sciences0302 clinical medicineIncisorPredictive Value of TestsOdds RatioPrevalenceHumansMedicine030212 general & internal medicineChildOrthodonticsMultidisciplinaryDentitionbusiness.industry030206 dentistryOdds ratioMolar Incisor HypomineralizationMolarIncisorCross-Sectional Studiesmedicine.anatomical_structurePredictive value of testsCohortDental Enamel HypoplasiaFemalebusiness
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Impact of temporomandibular disorders on the stomatognathic system in children

2017

Background To evaluate the EMG activity and thickness of right masseter (RM), left masseter (LM), right temporal (RT) and left temporal (LT) muscles and bite force in children with temporomandibular disorders (TMD). Material and Methods Forty five children (mean age 8.8 years; 22 boys and 23 girls) were examined on the basis of the RDC/TMD and the Faces Pain Scale-Revised (FPS-R) was used to determine the level of severity of the signs and symptoms of TMD, resulting in four groups: GI - without TMD (n=10); GII - with mild TMD (n=18), GIII: with moderate TMD (n=12) and GIV: with severe TMD (n=5). The data of electromyographic activity, maximum bite force and muscle thickness were tabulated a…

MaleMolarDentistryTemporal MuscleElectromyographySeverity of Illness IndexBite Force03 medical and health sciences0302 clinical medicineSeverity of illnessHumansMedicineChildStomatognathic SystemGeneral Dentistrymedicine.diagnostic_testElectromyographyMasseter Musclebusiness.industryResearch030206 dentistryTemporomandibular Joint DisordersMedically compromised patients in Dentistry:CIENCIAS MÉDICAS [UNESCO]Masticatory forceBite force quotientstomatognathic diseasesStomatognathic systemOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASLateralityFemaleSurgeryAnalysis of variancebusinesshuman activities030217 neurology & neurosurgery
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Molecular surveillance of pandemic influenza A(H1N1) viruses circulating in Italy from May 2009 to February 2010: association between haemagglutinin …

2010

Haemagglutinin sequences of pandemic influenza A(H1N1) viruses circulating in Italy were examined, focusing on amino acid changes at position 222 because of its suggested pathogenic relevance. Among 169 patients, the D222G substitution was detected in three of 52 (5.8%) severe cases and in one of 117 (0.9%) mild cases, whereas the D222E mutation was more frequent and evenly distributed in mild (31.6%) and severe cases (38.4%). A cluster of D222E viruses among school children confirms reported human-to-human transmission of viruses mutated at amino acid position 222.

MaleMolecular surveillance; Pandemic influenza A(H1N1); Haemagglutinin mutations; Italy from May 2009 to February 2010pandemic influenzasurveillance of pandemic influenza A(H1N1); Molecular surveillance; pandemic influenzaEpidemiologyvirusesHaemagglutinin mutationssurveillance of pandemic influenza A(H1N1)Settore MED/42 - Igiene Generale E Applicatamedicine.disease_causeSeverity of Illness IndexInfluenza A Virus H1N1 SubtypePandemic influenza A(H1N1)PandemicInfluenza A VirusA(H1N1)ChildMutationReverse Transcriptase Polymerase Chain ReactionTransmission (medicine)Adolescent; Adult; Age Distribution; Aged; Amino Acid Substitution; Child; Child Preschool; Female; Hemagglutinins; Humans; Infant; Influenza A Virus H1N1 Subtype; Influenza Human; Italy; Male; Middle Aged; Mutation; Population Surveillance; Reverse Transcriptase Polymerase Chain Reaction; Severity of Illness Index; Sex Distribution; Young Adult; PandemicsMiddle AgedItaly from May 2009 to February 2010Molecular surveillance; pandemic influenza; A(H1N1); Italy; haemagglutinin mutationsHemagglutininsMolecular surveillanceItalyChild PreschoolPopulation SurveillanceFemaleHumanAdultAdolescentBiologyDisease clusterDisease courseYoung AdultAge DistributionVirologyInfluenza HumanmedicineHumansH1N1 SubtypeSex DistributionPreschoolhaemagglutinin mutationsPandemicsAgedMolecular epidemiologyPublic Health Environmental and Occupational HealthPandemic influenzaInfantVirologyInfluenzaMutational analysisAmino Acid SubstitutionMutationEurosurveillance
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Is it wrong to deliberately conceive or give birth to a child with mental retardation?

2002

This paper discusses the issues of deciding to have a child with mental retardation, and of terminating a pregnancy when the future child is known to have the same disability. I discuss these problems by criticizing a utilitarian argument, namely, that one should act in a way that results in less suffering and less limited opportunity in the world. My argument is that future parents ought to assume a strong responsibility towards the well-being of their prospective children when they decide to reproduce. The moral point in cases in which our acts affect the well-being of future children should be expressed strictly in terms of parents' culpability. Future children thus do not have current m…

MaleMoral ObligationsParentsHealth Knowledge Attitudes PracticeWrongful LifeAbortionArgumentPregnancyIntellectual DisabilityEugenicsmedicineWrongful lifeHumansSociologyBioethical IssuesGenetic TestingChildPhilosophical methodologySocial ResponsibilityGeneral MedicineMental illnessmedicine.diseasehumanitiesDisabled ChildrenPhilosophyIssues ethics and legal aspectsFemaleEthical TheorySocial responsibilitySocial psychologyAbortion EugenicCulpabilityThe Journal of medicine and philosophy
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Fatigue, Physical Disability and Self-Efficacy as Predictors of the Acceptance of Illness and Health-Related Quality of Life in Patients with Multipl…

2021

Multiple sclerosis (MS) is a chronic progressive demyelinating disease of the central nervous system that leads to permanent disability and many neurological symptoms, making everyday functioning difficult. The predictors of the acceptance of illness and the health-related quality of life in people with MS include the degree of disability, neurological symptoms and psychosocial factors, such as personal resources. The aim of our study is to determine the relationships among disability, fatigue, self-efficacy, acceptance of illness and quality of life. The study group consisted of 137 people diagnosed with multiple sclerosis—73 women and 64 men. EDSS, GNDS, LSES, AIS and MSIS-29 were u…

MaleMultiple Sclerosisacceptance of illnessHealth Toxicology and MutagenesisPublic Health Environmental and Occupational HealthRSelf EfficacyArticledisabilityquality of lifeMedicineHumansDisabled PersonsFemalefatiguemultiple sclerosis; fatigue; disability; self-efficacy; acceptance of illness; quality of lifeself-efficacyInternational journal of environmental research and public health
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Management of elderly patients suffering from cancer: Assessment of perceived burden and of quality of life of primary caregivers

2017

International audience; Objective: To evaluate the perceived burden and the quality of life (QoL) at 3 and 6 months of the primary caregiver (PC) of patients aged 70 and over suffering from cancer and the predictors of QoL in this population.Methods: In this prospective observational study, 98 patients aged 70 and older with cancer and 96 PCs were included between 01/06/2014 and 18/03/2015. The Medical Outcomes Study 12-item Short Form Health Survey (SF-12) was used to assess the QoL of PCs and the Zarit Burden Interview (ZBI) was used to measure the perceived burden at 3 and 6 months. The major determinants of QoL were identified using mixed linear models for the dimensions of the SF-12 th…

MaleMultivariate analysisActivities of daily livingTime Factors0302 clinical medicineQuality of lifeCost of IllnessNeoplasmsSurveys and QuestionnairesActivities of Daily Living030212 general & internal medicineLongitudinal StudiesProspective StudiesProspective cohort studyPrimary caregiverAged 80 and overeducation.field_of_studyFamily caregivers[SDV.MHEP.GEG]Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontologyillnessAge FactorsMiddle Agedcomprehensive geriatric assessmentolder patientshumanities3. Good healthcomorbidityOncologyCaregivers030220 oncology & carcinogenesisdepressionDisease ProgressionimpactFemalefamily caregiversoncology consultationQuality of lifemedicine.medical_specialtyGeriatric oncology consultationPopulationBurden[ SDV.MHEP.GEG ] Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontology03 medical and health sciencesmedicineHumanscareeducationbreast-cancerbusiness.industrymedicine.diseaseComorbidityPhysical therapyObservational studyGeriatrics and Gerontologybusiness
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End Cutaneous Ureterostomy for the Management of Severe Hydronephrosis

2007

Purpose: Although rarely indicated, surgical treatment of severe megaureter can pose a formidable technical challenge, especially in the small infant. We present our experience and outcomes with end cutaneous ureterostomy as a temporizing adjunct to future ureteral reimplantation. Materials and Methods: We performed a retrospective cohort study of patients who underwent end cutaneous ureterostomy between 1993 and 2005. Patient demographics, surgical details and outcomes were recorded. Results: A total of 29 patients (22 males, 7 females) underwent diversion of 34 renal units. Primary megaureter was diagnosed in 15 patients (17 renal units). Secondary megaureter was found in 10 patients (12 …

MaleNephrologymedicine.medical_specialtyMegaureterUrologymedicine.medical_treatmentDermatologic Surgical ProceduresHydronephrosisSeverity of Illness IndexVesicoureteral refluxCohort StudiesUreterostomyInternal medicinemedicineHumansChildHydronephrosisUreterostomyRetrospective Studiesbusiness.industryUrinary diversionInfantRetrospective cohort studymedicine.diseaseSurgeryChild PreschoolFemaleureterostomy urinary diversion hydronephrosisbusinessKidney diseaseJournal of Urology
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