Search results for "imination"

showing 10 items of 605 documents

Le sentiment de discrimination des descendants d'immigrés : reflet d'une orientation contrariée et d'un chômage persistant

2012

National audience; La discrimination est analysée ici en croisant les perceptions des jeunes avec la réalité de leur insertion sur le marché du travail et de leur parcours d'éducation. Une orientation contrariée en fin de troisième a un impact sur les trajectoires ultérieures, comme l'obtention d'un emploi. Certes, le chômage est lié au niveau d'études, mais les descendants d'immigrés originaires du Maghreb ou d'Afrique subsaharienne y sont surexposés, mettant en relief une discrimination à l'embauche, discrimination vivement ressentie par les jeunes eux-mêmes.

050402 sociology[SHS.EDU]Humanities and Social Sciences/Education05 social sciences[SHS.EDU] Humanities and Social Sciences/EducationInsertion professionnelle050301 educationOcean EngineeringEnfant de migrant[ SHS.EDU ] Humanities and Social Sciences/Education16. Peace & justiceOrientation scolaire et professionnelle0504 sociologyChômageDiscriminationJeunePerception10. No inequality0503 education
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An extensive pattern of atypical neural speech-sound discrimination in newborns at risk of dyslexia.

2019

Objective: Identifying early signs of developmental dyslexia, associated with deficient speech-sound processing, is paramount to establish early interventions. We aimed to find early speech-sound processing deficiencies in dyslexia, expecting diminished and atypically lateralized event-related potentials (ERP) and mismatch responses (MMR) in newborns at dyslexia risk. Methods: ERPs were recorded to a pseudoword and its variants (vowel-duration, vowel-identity, and syllable-frequency changes) from 88 newborns at high or no familial risk. The response significance was tested, and group, laterality, and frontality effects were assessed with repeated-measures ANOVA. Results: An early positive a…

6162 Cognitive scienceMaleSpeech soundAudiologyEvent-related potential (ERP)Dyslexia0302 clinical medicineEARLY LANGUAGE-ACQUISITIONnewbornMedicineFAMILIAL RISKAuditoryBRAIN RESPONSES05 social sciencesevent-related potential (ERP)ElectroencephalographySensory SystemsLanguage developmentNeurologyLateralityEvoked Potentials AuditorySpeech PerceptionFemaleAnalysis of variancespeech soundpsychological phenomena and processesmedicine.medical_specialty515 PsychologyMISMATCH NEGATIVITY MMNCORTICAL RESPONSESEVENT-RELATED POTENTIALSGENETIC RISKbehavioral disciplines and activities050105 experimental psychology03 medical and health sciencesSpeech discriminationEvent-related potentialPhoneticsPhysiology (medical)Vowelotorhinolaryngologic diseasesdysleksiaHumansSpeech0501 psychology and cognitive sciencesauditoryAUDITORY-DISCRIMINATIONMismatch response (MMR)vastasyntyneetAuditory Cortexbusiness.industrypuheääni3112 NeurosciencesDyslexiaInfant NewbornNewbornmismatch response (MMR)medicine.diseaseta3124PseudowordPHONEME MISMATCHAcoustic StimulationDEVELOPMENTAL DYSLEXIANeurology (clinical)business030217 neurology & neurosurgeryClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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Discriminación indirecta por pertenencia a minoría nacional : denegación de prestación de viudedad en el caso de matrimonio celebrado según el rito g…

2021

The commented sentence rejects that the Muñoz Díaz doctrine is applicable to all cases of gypsy marriage. In addition, it considers that the denial of effects to the union celebrated according to said rite is not discriminatory. This conclusion is discussed, understanding that the analysis of the singularities of the gypsy people must lead to the conclusion of the existence of indirect discrimination.

:CIENCIAS JURÍDICAS [UNESCO]Indirect discriminationviudedadgypsy rite 1032 1051understanding that the analysis of the singularities of the gypsy people must lead to the conclusion of the existence of indirect discrimination. Discriminación indirectaminoría nacionalrito gitano2070-8157 22082 Revista Boliviana de Derecho 584568 2021 32 8055248 Discriminación indirecta por pertenencia a minoría nacional denegación de prestación de viudedad en el caso de matrimonio celebrado según el rito gitano. Comentario de la STC de España 1/2021UNESCO::CIENCIAS JURÍDICASAntonio The commented sentence rejects that the Muñoz Díaz doctrine is applicable to all cases of gypsy marriage. In additionwidowhoodde 25 de enero) Folgoso Olmoit considers that the denial of effects to the union celebrated according to said rite is not discriminatory. This conclusion is discussednational minority
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Different approaches to marriage downgrading : from an anti-elusive measure to an antidiscriminatory claim

2021

The essay focuses on the different mechanisms of marriage downgrading. Given the principle of ?cross-border continuity? of statuses, limits to this continuity are sometimes admitted and they are placed through downgrading mechanisms. That can occour in the case of same-sex marriages transcription in a Member State which does not allow such marriages, but which does allow samesex registered partnerships. Downgrading mechanism has an anti-elusive function, but it is not without problems in terms of discrimination on the grounds of sexual orientation. A different approach is taken in the case of an opposite-sex couple requesting the downgrading of their marriage, celebrated before the Member S…

:CIENCIAS JURÍDICAS [UNESCO]cross-border coupleregistered partnershippareja transfronterizadiscriminación. 130 147but which does allow samesex registered partnerships. Downgrading mechanism has an anti-elusive functiondowngradingRoberto The essay focuses on the different mechanisms of marriage downgrading. Given the principle of ?cross-border continuity? of statuseslimits to this continuity are sometimes admitted and they are placed through downgrading mechanisms. That can occour in the case of same-sex marriages transcription in a Member State which does not allow such marriagesbut it is not without problems in terms of discrimination on the grounds of sexual orientation. A different approach is taken in the case of an opposite-sex couple requesting the downgrading of their marriagedegradaciónUNESCO::CIENCIAS JURÍDICAScelebrated before the Member State allowed access to registered partnerships for all sex couples. The element of voluntariness seems to be the prerequisite for a proper anti-discrimination rule FamilyFamiliamatrimonio2386-4567 22661 Actualidad jurídica iberoamericana 587897 2021 15 8113553 Different approaches to marriage downgrading from an anti-elusive measure to an antidiscriminatory claim Garettouniones registradasmarriagediscrimination.
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La patria potestad prorrogada y la patria potestad rehabilitada en el nuevo proyecto de ley de reforma de la legislación civil y procesal para el apo…

2021

It is intended to analyze and reflect in the present work about the institution of the extension of parental authority and parental authority rehabilitated in the new regulation in the Draft Law that reforms the civil and procedural legislation to support people with disabilities in the exercise of their legal capacity. In this project, the extended parental authority and the rehabilitated parental authority are eliminated from the scope of disability, following a criterion that demands the treatment of people with disabilities with the attention that their specific situation requires, eliminating a regime that seems contrary to the system of promoting the autonomy of adults with disabiliti…

:CIENCIAS JURÍDICAS [UNESCO]parental authorityrehabilitacióneliminating a regime that seems contrary to the system of promoting the autonomy of adults with disabilities. This study is linked and addressedas they will be affected by the reform and by the effect of the structural deficiencies suffered by the Justice system of our country. the present work about the institution of the extension of parental authority and parental authority rehabilitated in the new regulation in the Bill of Law that reforms the civil and procedural legislation to support people with disabilities in the exercise of its legal capacity. In this projectelimination 236 251eliminaciónrehabilitationPablo It is intended to analyze and reflect in the present work about the institution of the extension of parental authority and parental authority rehabilitated in the new regulation in the Draft Law that reforms the civil and procedural legislation to support people with disabilities in the exercise of their legal capacity. In this projectprojectproyectoUNESCO::CIENCIAS JURÍDICASthe extended parental authority and the rehabilitated parental authority are eliminated from the scope of disabilitypatria potestadExtensionwith the characteristics and needs of people with a severe intellectual disabilityas they will be affected by the reform and by the effect of the structural insufficiencies suffered by the Justice system of our country. Prórroga2070-8157 22082 Revista Boliviana de Derecho 584568 2021 32 8055222 La patria potestad prorrogada y la patria potestad rehabilitada en el nuevo proyecto de ley de reforma de la legislación civil y procesal para el apoyo a las personas con discapacidad (actual ley 8/2021) Tortajada Chardífollowing a criterion that demands the treatment of people with disabilities with the attention that their specific situation requireshealth care economics and organizations
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The impact of direct acting antivirals on hepatitis C virus disease burden and associated costs in four European countries

2021

Eliminació del VHC; Punt d'equilibri; Infecció d'hepatitis C Eliminación del VHC; Punto de equilibrio; Infección de hepatitis C HCV elimination; Break-even; Hepatitis C infection Background and Aims We assessed the clinical and economic impact of direct-acting antiviral (DAA) therapy for hepatitis C virus (HCV) in England, Italy, Romania and Spain. Methods An HCV progression Markov model was developed considering DAA eligibility and population data during the years 2015-2019. The period of time to recover the investment in DAAs was calculated as the cost saved by avoiding estimated clinical events for 1000 standardized treated patients. A delayed treatment scenario because of coronavirus di…

:Health Care Economics and Organizations::Economics::Costs and Cost Analysis::Cost Control::Cost Savings [HEALTH CARE]DiseaseHepacivirusmedicine.disease_cause:Digestive System Diseases::Liver Diseases::Hepatitis::Hepatitis Viral Human::Hepatitis C [DISEASES]0302 clinical medicineCost of IllnessMedicine:Other subheadings::/therapeutic use [Other subheadings]Economic impact analysisChronicExit strategyevenLiver NeoplasmsHealth services researchhealthInvestment (macroeconomics)Hepatitis C:Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Antiviral Agents [CHEMICALS AND DRUGS]break‐EnglandItalyHCV elimination030220 oncology & carcinogenesisOriginal Article030211 gastroenterology & hepatologyLiver Disease and Public HealthHumanHepatitis C virusSettore SECS-P/03hepatitis C infectionMedicaments antivírics- Ús terapèuticAntiviral AgentsTime-to-Treatment03 medical and health sciencesbreak-evenHumansbusinessDisease burdenDAAAntiviral Agent:economía y organizaciones para la atención de la salud::economía::costes y análisis de costes::control de costes::ahorro de costes [ATENCIÓN DE SALUD]HepaciviruHepatology:Otros calificadores::/uso terapéutico [Otros calificadores]business.industryRomania:enfermedades del sistema digestivo::enfermedades hepáticas::hepatitis::hepatitis viral humana::hepatitis C [ENFERMEDADES]COVID-19break‐evenDAAsHepatitis C ChronicEstalvi i inversióHcv eliminationCost of IllneSpain:acciones y usos químicos::acciones farmacológicas::usos terapéuticos::antiinfecciosos::antivíricos [COMPUESTOS QUÍMICOS Y DROGAS]Communicable Disease ControlVirus de l'hepatitis CbusinessDemography
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Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo

2021

Multidrug resistance (MDR) mediated by ATP binding cassette subfamily B member 1 (ABCB1) is significantly hindering effective cancer chemotherapy. However, currently, no ABCB1-inhibitory drugs have been approved to treat MDR cancer clinically, mainly due to the inhibitor specificity, toxicity, and drug interactions. Here, we reported that three polyoxypregnanes (POPs) as the most abundant constituents of Marsdenia tenacissima (M. tenacissima) were novel ABCB1-modulatory pro-drugs, which underwent intestinal microbiota-mediated biotransformation in vivo to generate active metabolites. The metabolites at non-toxic concentrations restored chemosensitivity in ABCB1-overexpressing cancer cells v…

ABCC1 ATP binding cassette subfamily C member 1IC50 half maximal inhibitory concentrationMultidrug resistancePharmacologyNADPH reduced nicotinamide adenine dinucleotide phosphateF bioavailabilitychemistry.chemical_compoundPCR polymerase chain reaction0302 clinical medicineMDR multidrug resistanceECL electrochemiluminescencet1/2 elimination half-lifeLC–MS liquid chromatography coupled with mass spectrometryN.D. not detectedGeneral Pharmacology Toxicology and PharmaceuticsBBB blood–brain barriermedia_commonATF3 activating transcription factor 30303 health sciencesChemistryABC ATP-binding cassetteNMPA National Medical Products AdministrationPXR pregnane X receptorSDS-PAGE sodium dodecyl sulfate-polyacrylamide gel electrophoresisHBSS Hankʹs balanced salt solutionABCB1Combination chemotherapyProdrugMarsdenia tenacissimaCmax peak concentrationPaclitaxelGAPDH glyceraldehyde-3-phosphate dehydrogenase030220 oncology & carcinogenesisBHI brain heart infusionOriginal ArticleAUC0–∞ area under plasma concentration vs. time curveMRT mean residence timeDrugmedia_common.quotation_subjectRM1-950Vd volume of distributionABCB1 ATP binding cassette subfamily B member 1UIC-2 mouse monoclonal ABCB1 antibodyABCG2 ATP binding cassette subfamily G member 2Combination chemotherapyCYP cytochrome P450 isozymePI propidium iodideTEER transepithelial electrical resistance03 medical and health sciencesPBS phosphate buffer salineFBS fetal bovine serumDox doxorubicinIn vivoPOP polyoxypregnanemedicine030304 developmental biologyEVOM epithelial tissue voltohmmeterTmax time for peak concentrationCancerLBE lowest binding energyPE phycoerythrinmedicine.diseaseMultiple drug resistancePolyoxypregnanePapp apparent permeabilityN.A. not applicableCancer cellH&E hematoxylin and eosinMDR1a multidrug resistance protein 1aTherapeutics. PharmacologyqPCR quantitative PCRM. tenacissima Marsdenia tenacissimaCL clearanceSD standard derivationActa Pharmaceutica Sinica B
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Specific transfer effects following variable priority dual-task training in older adults

2016

International audience; Purpose: Past divided attention training studies in older adults have suggested that variable priority training (VPT) tends to show larger improvement than fixed priority training (FPT). However, it remains unclear whether VPT leads to larger transfer effects. Methods: In this study, eighty-three older adults aged between 55 and 65 received five 1-hour sessions of VPT, FPT or of an active placebo. VPT and FPT subjects trained on a complex dual-task condition with variable stimulus timings in order to promote more flexible and self-guided strategies with regard to attentional priority devoted to the concurrent tasks. Real-time individualized feedback was provided to e…

Active placeboMalemedicine.medical_specialtyAgingComputer User TrainingTransfertTransfer Psychology[ SCCO.PSYC ] Cognitive science/PsychologyStimulus (physiology)Neuropsychological Tests050105 experimental psychology[ SDV.NEU.PC ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationDiscrimination PsychologicalDevelopmental NeuroscienceComputer User TrainingmedicineReaction TimeHumans0501 psychology and cognitive sciencesAttentionAgedAnalysis of Variance[SDV.NEU.PC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behaviorTeaching[SCCO.NEUR]Cognitive science/Neuroscience05 social sciencesMiddle AgedDivided attentionCognitive trainingVariable priority trainingNeurologyPattern Recognition VisualCognitive trainingDivided attentionOlder adults[SCCO.PSYC]Cognitive science/Psychology[ SCCO.NEUR ] Cognitive science/NeuroscienceFemaleNeurology (clinical)Analysis of varianceIndependent LivingPsychology030217 neurology & neurosurgery
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Contra la patologización intensiva en términos de derechos humanos: Activismo gordo en Argentina

2020

This work addresses the way in which Argentine Fat Activism has developed, in recent years, the demand for depathologization of fatness, taking elements from critical discourses on the health of fat people to frame them in a perspective typical of the Human Rights. First, the contemporary fat body is described in terms of stigma and discrimination, especially in the health field. Then, they refer to a series of critical positions on the pathologization and medicalization of fatness from the biomedical perspective, Fat Studies and Fat Activism. Lastly, a series of interventions that the Argentine activist collective Taller Hacer la Vista Gorda produced between 2017 and 2020 were considered, …

Activismo gordo en Argentina Contrera [1137-7038 8537 Arxius de sociologia 562372 2020 42 7674040 Contra la patologización intensiva en términos de derechos humanos]in recent yearsDespatologización.Human RightsFat Studiesespecially in the health field. Thenthe contemporary fat body is described in terms of stigma and discriminationthey refer to a series of critical positions on the pathologization and medicalization of fatness from the biomedical perspectivea series of interventions that the Argentine activist collective Taller Hacer la Vista Gorda produced between 2017 and 2020 were consideredCOVID-19:SOCIOLOGÍA [UNESCO]and highlights the innovation of the local turn in the current context of pandemic. Estudios Sobre GorduraActivismo Gordo1137-7038 8537 Arxius de sociologia 562372 2020 42 7674040 Contra la patologización intensiva en términos de derechos humanos: Activismo gordo en Argentina ContreraDerechos HumanosDepathologization 175 188focusing on the claim of depathologizationUNESCO::SOCIOLOGÍAFat Studies and Fat Activism. Lastlythe demand for depathologization of fatnesstaking elements from critical discourses on the health of fat people to frame them in a perspective typical of the Human Rights. FirstFat ActivismLaura This work addresses the way in which Argentine Fat Activism has developed
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Auditory Event-Related Potentials in the Study of Developmental Language-Related Disorders

1997

This article reviews recent auditory event-related potential (ERP) studies of developmental language disorder (DLD) and dyslexia/reading disorder (RD). The possibility of using ERPs in searching for precursors of these disorders in the early development of infants at risk is also discussed. Differences in exogenous/sensory ERPs at the latency range of P1 and N1-P2 components have been reported between groups with DLD and RD and control groups. Latency differences between the groups may be related to a common timing deficit suggested by some researchers to be one of the possible underlying factors both in DLD and dyslexia. N1 amplitude group differences may be partly related to arousal/atten…

AdolescentPhysiologyMismatch negativityFunctional LateralityDyslexiaSpeech and HearingPhoneticsCommunication disorderEvent-related potentialmedicineHumansLanguage disorderChildSensory memoryDyslexiaBrainCognitionmedicine.diseaseSensory SystemsDevelopmental disorderOtorhinolaryngologyChild PreschoolEvoked Potentials AuditorySpeech Discrimination TestsSpeech PerceptionPsychologyNeuroscienceAudiology and Neurotology
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