Search results for "imulation"
showing 10 items of 7271 documents
L’apport de la simulation multi-agent du trafic routier pour l’estimation des pollutions atmosphériques automobiles
2015
National audience; La pollution atmosphérique est aujourd’hui considérée comme cancérigène pour la santé humaine (OMS, 2013). Avec le bruit, elle est l’une des premières nuisances directement ressenties par les populations en milieu urbain. Son évaluation présente un véritable enjeu pour les pouvoirs publics afin de mieux en identifier ses sources, ses impacts en vue de définir des politiques territoriales (PDU, cadastre d’émission). A l’échelle locale, la pollution atmosphérique est à relier directement à l’intensité des sources d’émissions qui vont accentuer, ou non, la qualité de l’air extérieure (Elichegaray, 2010) . En milieu urbain, le premier contributeur en émission de NOx, CO, ou P…
Case-specific performance of MM-PBSA, MM-GBSA, and SIE in virtual screening.
2015
In drug discovery the reliable prediction of binding free energies is of crucial importance. Methods that combine molecular mechanics force fields with continuum solvent models have become popular because of their high accuracy and relatively good computational efficiency. In this research we studied the performance of molecular mechanics generalized Born surface area (MM-GBSA), molecular mechanics Poisson-Boltzmann surface area (MM-PBSA), and solvated interaction energy (SIE) both in their virtual screening efficiency and their ability to predict experimentally determined binding affinities for five different protein targets. The protein-ligand complexes were derived with two different app…
Enhancing the performance of HSDPA communication with multipoint transmission techniques
2015
The evolution of mobile phones, tablets and other mobile communication devices has led to a significant increase in the amount of data delivered over mobile networks. In order to satisfy the climbing data rate demands of customers, existing mobile broadband networks are being expanded with new features that allow ubiquitous and consistent networking experience. This research presents three multipoint transmission techniques for Wideband Code Division Multiple Access (WCDMA) based High-Speed Downlink Packet Access (HSDPA) communication protocol. Multiflow, High-Speed Single-Frequency Network (HS-SFN) and Multipoint-to-Point Single-Frequency Network (M2P-SFN) enable transmission of user-dedicat…
Performance Enhancement of a Small Animal Positron Emission Tomograph based on Continuous Crystals and Silicon Photomultipliers
2017
La tomografía por emisión de positrones (PET, por sus siglas en inglés) es una técnica de Medicina Nuclear que permite obtener de manera no invasiva imágenes funcionales “in vivo” marcando un compuesto orgánico con un emisor de positrones. Los tomógrafos PET requieren un alta resolución espacial y sensibilidad para estimar con precisión la distribución del radiotrazador en el animal. Frente a los bloques pixelados comúnmente utilizados en PET, los detectores que consisten en la combinación de cristales continuos acoplados a fotodetectores segmentados pueden ofrecer una mayor eficiencia y una alta resolución espacial. Esta última depende de la precisión de los algoritmos de determinación de …
Transcranial direct current stimulation for treatment of freezing of gait: a cross-over study.
2014
BACKGROUND AND OBJECTIVE: Progression of Parkinson's disease (PD) is frequently characterized by the occurrence of freezing of gait (FOG) representing a disabling motor complication. We aim to investigate safety and efficacy of transcranial direct current stimulation of the primary motor cortex of PD patients with FOG. METHODS: In this cross-over, double-blind, sham-controlled study, 10 PD patients with FOG persisting in "on" state underwent anodal and sham direct current stimulation for 5 consecutive days. Clinical assessment over a 1-month period was performed. RESULTS: A significant improvement of gait, as assessed by the Stand Walk Sit test, with reduction in number and duration of FOG …
Potentiation Of Oropharyngeal Swallowing Through Transcranial Direct Current Stimulation (Tdcs): Functional And Electrophysiological Meausures Of Mot…
2011
The effect of transient visual deprivation on motor cortical excitability and motor learning : a pilot study
2016
Castro, Fabio, 2015. The Effect of Transient Visual Deprivation on Motor Cortical Excitability and Motor Learning. University of Jyväskylä, Department of Biology of Physical Activity, Master Thesis in Applied Biomechanics. 86 pp. We devised an experimental protocol to test the hypothesis that if the performer poses attention on the proprioceptive signals, in the form of awareness of the body in space, this could increase the corticospinal excitability and the overall performance. 10 right-handed volunteers were randomly assigned to either a group performing a skill training blindfolded (BLIND) or in normal (NORM) condition. The intervention included a visuomotor task-related skill training …
Représentation, analyse et caractérisation de surfaces rugueuses
2020
Nous présentons un projet de recherche dans lequel, nous proposons d’aborder la problématique de la représentation numérique, de l’analyse et de la caractérisation de surfaces rugueuses. La rugosité est un concept complexe, par nature multi-échelle et reposant sur l’étude du comportement local d’une surface dans un voisinage donné. Son évaluation sur les surfaces est essentielle pour de nombreux problèmes expérimentaux. Cela explique les nombreuses études réalisées dans les domaines applicatifs liés à la physique et la mécanique, là où le contrôle et la maîtrise de l’état des surfaces constituent un besoin majeur pour les industriels. Un grand nombre de paramètres conventionnels normalisés …
Conditional predictive inference for online surveillance of spatial disease incidence
2011
This paper deals with the development of statistical methodology for timely detection of incident disease clusters in space and time. The increasing availability of data on both the time and the location of events enables the construction of multivariate surveillance techniques, which may enhance the ability to detect localized clusters of disease relative to the surveillance of the overall count of disease cases across the entire study region. We introduce the surveillance conditional predictive ordinate as a general Bayesian model-based surveillance technique that allows us to detect small areas of increased disease incidence when spatial data are available. To address the problem of mult…
Highly-parallelized simulation of a pixelated LArTPC on a GPU
2023
The rapid development of general-purpose computing on graphics processing units (GPGPU) is allowing the implementation of highly-parallelized Monte Carlo simulation chains for particle physics experiments. This technique is particularly suitable for the simulation of a pixelated charge readout for time projection chambers, given the large number of channels that this technology employs. Here we present the first implementation of a full microphysical simulator of a liquid argon time projection chamber (LArTPC) equipped with light readout and pixelated charge readout, developed for the DUNE Near Detector. The software is implemented with an end-to-end set of GPU-optimized algorithms. The alg…